aph-1 and pen-2 are required for Notch pathway signaling, γ-secretase cleavage of βAPP, and presenilin protein accumulation R Francis, G McGrath, J Zhang, DA Ruddy, M Sym, J Apfeld, M Nicoll, ... Developmental cell 3 (1), 85-97, 2002 | 1156 | 2002 |
Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome AL Parks, KR Cook, M Belvin, NA Dompe, R Fawcett, K Huppert, LR Tan, ... Nature genetics 36 (3), 288-292, 2004 | 916 | 2004 |
Ligand endocytosis drives receptor dissociation and activation in the Notch pathway AL Parks, KM Klueg, JR Stout, MAT Muskavitch Development 127 (7), 1373-1385, 2000 | 677 | 2000 |
The transgenic RNAi project at Harvard Medical School: resources and validation LA Perkins, L Holderbaum, R Tao, Y Hu, R Sopko, K McCall, ... Genetics 201 (3), 843-852, 2015 | 656 | 2015 |
Safeguarding gene drive experiments in the laboratory OS Akbari, HJ Bellen, E Bier, SL Bullock, A Burt, GM Church, KR Cook, ... Science 349 (6251), 927-929, 2015 | 348 | 2015 |
Presenilin diversifies its portfolio AL Parks, D Curtis Trends in Genetics 23 (3), 140-150, 2007 | 200 | 2007 |
Relationships between complex Delta expression and the specification of retinal cell fates during Drosophila eye development AL Parks, FR Turner, MAT Muskavitch Mechanisms of development 50 (2-3), 201-216, 1995 | 164 | 1995 |
Delta function is required for bristle organ determination and morphogenesis in Drosophila AL Parks, MA Muskavitch Developmental biology 157 (2), 484-496, 1993 | 132 | 1993 |
Structure–function analysis of Delta trafficking, receptor binding and signaling in Drosophila AL Parks, JR Stout, SB Shepard, KM Klueg, AA Dos Santos, TR Parody, ... Genetics 174 (4), 1947-1961, 2006 | 128 | 2006 |
Localization and expression of msp130, a primary mesenchyme lineagespecific cell surface protein of the sea urchin embryo JA Anstrom, JE Chin, DS Leaf, AL Parks, RA Raff Development 101 (2), 255-265, 1987 | 120 | 1987 |
The dynamics of neurogenic signalling underlying bristle development in Drosophila melanogaster AL Parks, SS Huppert, MAT Muskavitch Mechanisms of development 63 (1), 61-74, 1997 | 118 | 1997 |
Large-Scale Transgenic Drosophila Resource Collections for Loss- and Gain-of-Function Studies J Zirin, Y Hu, L Liu, D Yang-Zhou, R Colbeth, D Yan, B Ewen-Campen, ... Genetics 214 (4), 755-767, 2020 | 110 | 2020 |
Molecular analysis of heterochronic changes in the evolution of direct developing sea urchins AL Parks, BA Parr, JE Chin, DS Leaf, RA Raff Journal of Evolutionary Biology 1 (1), 27-44, 1988 | 106 | 1988 |
Engineered truncations in the Drosophila mastermind protein disrupt Notch pathway function W Helms, H Lee, M Ammerman, AL Parks, MAT Muskavitch, ... Developmental biology 215 (2), 358-374, 1999 | 105 | 1999 |
New research resources at the bloomington drosophila stock center KR Cook, AL Parks, LM Jacobus, TC Kaufman, K Matthews Fly 4 (1), 88-91, 2010 | 67 | 2010 |
Direct Development in the Sea Urchin Phyllacanthus parvispinus (Cidaroidea): Phylogenetic History and Functional Modification AL Parks, BW Bisgrove, GA Wray, RA Raff The Biological Bulletin 177 (1), 96-109, 1989 | 64 | 1989 |
Presenilin-Based Genetic Screens in Drosophila melanogaster Identify Novel Notch Pathway Modifiers MB Mahoney, AL Parks, DA Ruddy, SYK Tiong, H Esengil, AC Phan, ... Genetics 172 (4), 2309-2324, 2006 | 59 | 2006 |
Promoter structure and protein sequence of msp130, a lipid-anchored sea urchin glycoprotein. BA Parr, AL Parks, RA Raff Journal of Biological Chemistry 265 (3), 1408-1413, 1990 | 47 | 1990 |
Heterochrony and other mechanisms of radical evolutionary change in early development RA Raff, BA Parr, AL Parks, GA Wray, MH Nitecki Evolutionary innovations, 71-98, 1990 | 44 | 1990 |
A screen for modifiers of notch signaling uncovers Amun, a protein with a critical role in sensory organ development NA Shalaby, AL Parks, EJ Morreale, MC Osswalt, KM Pfau, EL Pierce, ... Genetics 182 (4), 1061-1076, 2009 | 38 | 2009 |