| Generating a prion with bacterially expressed recombinant prion protein F Wang, X Wang, CG Yuan, J Ma Science 327 (5969), 1132-1135, 2010 | 807 | 2010 |
| Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids NR Deleault, JR Piro, DJ Walsh, F Wang, J Ma, JC Geoghegan, ... Proceedings of the National Academy of Sciences 109 (22), 8546-8551, 2012 | 266 | 2012 |
| Cofactor molecules maintain infectious conformation and restrict strain properties in purified prions NR Deleault, DJ Walsh, JR Piro, F Wang, X Wang, J Ma, JR Rees, ... Proceedings of the National Academy of Sciences 109 (28), E1938-E1946, 2012 | 210 | 2012 |
| Lipid interaction converts prion protein to a PrPSc-like proteinase K-resistant conformation under physiological conditions F Wang, F Yang, Y Hu, X Wang, X Wang, C Jin, J Ma Biochemistry 46 (23), 7045-7053, 2007 | 124 | 2007 |
| Cofactor molecules induce structural transformation during infectious prion formation MB Miller, DW Wang, F Wang, GP Noble, J Ma, VL Woods, S Li, ... Structure 21 (11), 2061-2068, 2013 | 78 | 2013 |
| The interaction between cytoplasmic prion protein and the hydrophobic lipid core of membrane correlates with neurotoxicity X Wang, F Wang, L Arterburn, R Wollmann, J Ma Journal of Biological Chemistry 281 (19), 13559-13565, 2006 | 78 | 2006 |
| De novo generation of infectious prions with bacterially expressed recombinant prion protein Z Zhang, Y Zhang, F Wang, X Wang, Y Xu, H Yang, G Yu, C Yuan, J Ma The FASEB Journal 27 (12), 4768, 2013 | 77 | 2013 |
| Role of the highly conserved middle region of prion protein (PrP) in PrP− lipid interaction F Wang, S Yin, X Wang, L Zha, MS Sy, J Ma Biochemistry 49 (37), 8169-8176, 2010 | 75 | 2010 |
| Prion disease and the ‘protein-only hypothesis’ J Ma, F Wang Essays in biochemistry 56, 181-191, 2014 | 74 | 2014 |
| Genetic informational RNA is not required for recombinant prion infectivity F Wang, Z Zhang, X Wang, J Li, L Zha, CG Yuan, C Weissmann, J Ma Journal of virology 86 (3), 1874-1876, 2012 | 55 | 2012 |
| Cytoplasmic prion protein induces forebrain neurotoxicity X Wang, SL Bowers, F Wang, X Pu, RJ Nelson, J Ma Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1792 (6), 555-563, 2009 | 46 | 2009 |
| Calpain and other cytosolic proteases can contribute to the degradation of retro-translocated prion protein in the cytosol X Wang, F Wang, MS Sy, J Ma Journal of Biological Chemistry 280 (1), 317-325, 2005 | 45 | 2005 |
| Seeding specificity and ultrastructural characteristics of infectious recombinant prions JR Piro, F Wang, DJ Walsh, JR Rees, J Ma, S Supattapone Biochemistry 50 (33), 7111-7116, 2011 | 44 | 2011 |
| Self-propagating, protease-resistant, recombinant prion protein conformers with or without in vivo pathogenicity F Wang, X Wang, CD Orrú, BR Groveman, K Surewicz, R Abskharon, ... PLoS Pathogens 13 (7), e1006491, 2017 | 43 | 2017 |
| Conversion of bacterially expressed recombinant prion protein F Wang, X Wang, J Ma Methods 53 (3), 208-213, 2011 | 42 | 2011 |
| Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion R Abskharon, F Wang, A Wohlkonig, J Ruan, S Soror, G Giachin, ... PLoS pathogens 15 (12), e1008139, 2019 | 36 | 2019 |
| Structural attributes of mammalian prion infectivity: Insights from studies with synthetic prions Q Li, F Wang, X Xiao, C Kim, J Bohon, J Kiselar, JG Safar, J Ma, ... Journal of Biological Chemistry 293 (48), 18494-18503, 2018 | 35 | 2018 |
| Intraperitoneal infection of wild-type mice with synthetically generated mammalian prion X Wang, G McGovern, Y Zhang, F Wang, L Zha, M Jeffrey, J Ma PLoS Pathogens 11 (7), e1004958, 2015 | 24 | 2015 |
| Prion infectivity is encoded exclusively within the structure of proteinase K-resistant fragments of synthetically generated recombinant PrPSc F Wang, X Wang, R Abskharon, J Ma Acta neuropathologica communications 6, 1-8, 2018 | 20 | 2018 |
| Recombinant PrPSc shares structural features with brain-derived PrPSc: Insights from limited proteolysis AM Sevillano, N Fernández-Borges, N Younas, F Wang, S R. Elezgarai, ... Plos Pathogens 14 (1), e1006797, 2018 | 20 | 2018 |
