| Iminosugars as glycosidase inhibitors A Stütz Wiley-VCH, 1999 | 724 | 1999 |
| Iminosugars: From synthesis to therapeutic applications P Compain, OR Martin John Wiley & Sons, 2007 | 662 | 2007 |
| One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase RW Miles, PC Tyler, RH Furneaux, CK Bagdassarian, VL Schramm Biochemistry 37 (24), 8615-8621, 1998 | 344 | 1998 |
| Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes GA Kicska, L Long, H Hörig, C Fairchild, PC Tyler, RH Furneaux, ... Proceedings of the National Academy of Sciences 98 (8), 4593-4598, 2001 | 244 | 2001 |
| Transition State Structure of Purine Nucleoside Phosphorylase and Principles of Atomic Motion in Enzymatic Catalysis, A Fedorov, W Shi, G Kicska, E Fedorov, PC Tyler, RH Furneaux, ... Biochemistry 40 (4), 853-860, 2001 | 240 | 2001 |
| Liposomal delivery of antigen to human dendritic cells MJ Copland, MA Baird, T Rades, JL McKenzie, B Becker, F Reck, ... Vaccine 21 (9-10), 883-890, 2003 | 229 | 2003 |
| The 2.0 Å structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor W Shi, CM Li, PC Tyler, RH Furneaux, C Grubmeyer, VL Schramm, ... nature structural biology 6 (6), 588-593, 1999 | 211 | 1999 |
| Femtomolar transition state analogue inhibitors of 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli V Singh, GB Evans, DH Lenz, JM Mason, K Clinch, S Mee, GF Painter, ... Journal of Biological Chemistry 280 (18), 18265-18273, 2005 | 189 | 2005 |
| Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase A Lewandowicz, PC Tyler, GB Evans, RH Furneaux, VL Schramm Journal of Biological Chemistry 278 (34), 31465-31468, 2003 | 180 | 2003 |
| Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function W Shi, LM Ting, GA Kicska, A Lewandowicz, PC Tyler, GB Evans, ... Journal of Biological Chemistry 279 (18), 18103-18106, 2004 | 179 | 2004 |
| The 2.0 Å Structure of Malarial Purine Phosphoribosyltransferase in Complex with a Transition-State Analogue Inhibitor, W Shi, CM Li, PC Tyler, RH Furneaux, SM Cahill, ME Girvin, C Grubmeyer, ... Biochemistry 38 (31), 9872-9880, 1999 | 174 | 1999 |
| Purine-less Death in Plasmodium falciparumInduced by Immucillin-H, a Transition State Analogue of Purine Nucleoside Phosphorylase GA Kicska, PC Tyler, GB Evans, RH Furneaux, VL Schramm, K Kim Journal of Biological Chemistry 277 (5), 3226-3231, 2002 | 164 | 2002 |
| Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins LM Ting, W Shi, A Lewandowicz, V Singh, A Mwakingwe, MR Birck, ... Journal of Biological Chemistry 280 (10), 9547-9554, 2005 | 152 | 2005 |
| Transition-state analogs as inhibitors of human and malarial hypoxanthine-guanine phosphoribosyltransferases CM Li, PC Tyler, RH Furneaux, G Kicska, Y Xu, C Grubmeyer, ME Girvin, ... nature structural biology 6 (6), 582-587, 1999 | 136 | 1999 |
| Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum GA Kicska, PC Tyler, GB Evans, RH Furneaux, K Kim, VL Schramm Journal of Biological Chemistry 277 (5), 3219-3225, 2002 | 131 | 2002 |
| Exploring structure− activity relationships of transition state analogues of human purine nucleoside phosphorylase GB Evans, RH Furneaux, A Lewandowicz, VL Schramm, PC Tyler Journal of medicinal chemistry 46 (15), 3412-3423, 2003 | 129 | 2003 |
| Addition of Lithiated 9-Deazapurine Derivatives to a Carbohydrate Cyclic Imine: Convergent Synthesis of the Aza-C-nucleoside Immucillins GB Evans, RH Furneaux, TL Hutchison, HS Kezar, PE Morris, ... The Journal of organic chemistry 66 (17), 5723-5730, 2001 | 127 | 2001 |
| Prostaglandin E2-bisphosphonate conjugates: potential agents for treatment of osteoporosis L Gil, Y Han, EE Opas, GA Rodan, R Ruel, JG Seedor, PC Tyler, ... Bioorganic & medicinal chemistry 7 (5), 901-919, 1999 | 126 | 1999 |
| Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase GB Evans, RH Furneaux, A Lewandowicz, VL Schramm, PC Tyler Journal of medicinal chemistry 46 (24), 5271-5276, 2003 | 125 | 2003 |
| Synthesis of a Targeted Library of Heparan Sulfate Hexa‐to Dodecasaccharides as Inhibitors of β‐Secretase: Potential Therapeutics for Alzheimer’s Disease R Schwörer, OV Zubkova, JE Turnbull, PC Tyler Chemistry–A European Journal 19 (21), 6817-6823, 2013 | 115 | 2013 |
Richard H. FurneauxFerrier Research Institute, Victoria Univserity of Wellingtonยืนยันอีเมลแล้วที่ vuw.ac.nz