The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution K Cwiklinski, JP Dalton, PJ Dufresne, J La Course, DJL Williams, ... Genome biology 16, 1-13, 2015 | 312 | 2015 |
The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis*[S] K Cwiklinski, E de la Torre-Escudero, M Trelis, D Bernal, PJ Dufresne, ... Molecular & Cellular Proteomics 14 (12), 3258-3273, 2015 | 244 | 2015 |
A prospective view of animal and human Fasciolosis K Cwiklinski, SM O'neill, S Donnelly, JP Dalton Parasite immunology 38 (9), 558-568, 2016 | 241 | 2016 |
Fasciola hepatica vaccine: we may not be there yet but we’re on the right road V Molina-Hernández, G Mulcahy, J Pérez, Á Martínez-Moreno, S Donnelly, ... Veterinary parasitology 208 (1-2), 101-111, 2015 | 227 | 2015 |
Surface molecules of extracellular vesicles secreted by the helminth pathogen Fasciola hepatica direct their internalisation by host cells E de la Torre-Escudero, JQ Gerlach, APS Bennett, K Cwiklinski, ... PLoS neglected tropical diseases 13 (1), e0007087, 2019 | 118 | 2019 |
Infection by the helminth parasite Fasciola hepatica requires rapid regulation of metabolic, virulence, and invasive factors to adjust to its mammalian host K Cwiklinski, H Jewhurst, P McVeigh, T Barbour, AG Maule, J Tort, ... Molecular & Cellular Proteomics 17 (4), 792-809, 2018 | 114 | 2018 |
Pathogenicity and virulence of the liver flukes Fasciola hepatica and Fasciola Gigantica that cause the zoonosis Fasciolosis R Lalor, K Cwiklinski, NED Calvani, A Dorey, S Hamon, JL Corrales, ... Virulence 12 (1), 2839-2867, 2021 | 112 | 2021 |
Fasciola hepatica surface tegument: glycoproteins at the interface of parasite and host A Ravida, K Cwiklinski, AM Aldridge, P Clarke, R Thompson, JQ Gerlach, ... Molecular & Cellular Proteomics 15 (10), 3139-3153, 2016 | 77 | 2016 |
The cathepsin-like cysteine peptidases of trematodes of the genus Fasciola K Cwiklinski, S Donnelly, O Drysdale, H Jewhurst, D Smith, ... Advances in parasitology 104, 113-164, 2019 | 75 | 2019 |
Advances in Fasciola hepatica research using ‘omics’ technologies K Cwiklinski, JP Dalton International journal for parasitology 48 (5), 321-331, 2018 | 67 | 2018 |
Identification of putative markers of triclabendazole resistance by a genome-wide analysis of genetically recombinant Fasciola hepatica J Hodgkinson, K Cwiklinski, NJ Beesley, S Paterson, DJL Williams Parasitology 140 (12), 1523-1533, 2013 | 60 | 2013 |
Immune signatures of pathogenesis in the peritoneal compartment during early infection of sheep with Fasciola hepatica MT Ruiz-Campillo, V Molina Hernandez, A Escamilla, M Stevenson, ... Scientific reports 7 (1), 2782, 2017 | 57 | 2017 |
Fasciola hepatica Extracellular Vesicles isolated from excretory-secretory products using a gravity flow method modulate dendritic cell phenotype and activity A Murphy, K Cwiklinski, R Lalor, B O’Connell, MW Robinson, J Gerlach, ... PLoS neglected tropical diseases 14 (9), e0008626, 2020 | 56 | 2020 |
Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the … K Cwiklinski, MW Robinson, S Donnelly, JP Dalton BMC genomics 22, 1-16, 2021 | 54 | 2021 |
Tegument Glycoproteins and Cathepsins of Newly Excysted Juvenile Fasciola hepatica Carry Mannosidic and Paucimannosidic N-glycans A Garcia-Campos, A Ravida, DL Nguyen, K Cwiklinski, JP Dalton, ... PLoS Neglected Tropical Diseases 10 (5), e0004688, 2016 | 52 | 2016 |
Complex and dynamic transcriptional changes allow the helminth Fasciola gigantica to adjust to its intermediate snail and definitive mammalian hosts XX Zhang, K Cwiklinski, RS Hu, WB Zheng, ZA Sheng, FK Zhang, ... BMC genomics 20, 1-18, 2019 | 48 | 2019 |
Unexpected activity of a novel kunitz-type inhibitor: inhibition of cysteine proteases but not serine proteases D Smith, IG Tikhonova, HL Jewhurst, OC Drysdale, J Dvořák, ... Journal of Biological Chemistry 291 (37), 19220-19234, 2016 | 45 | 2016 |
New insights into sequence variation in the IGS region of 21 cyathostomin species and the implication for molecular identification K Cwiklinski, FNJ Kooyman, DCK Van Doorn, JB Matthews, ... Parasitology 139 (8), 1063-1073, 2012 | 43 | 2012 |
Fasciola hepatica hijacks host macrophage miRNA machinery to modulate early innate immune responses N Tran, A Ricafrente, J To, M Lund, TM Marques, M Gama-Carvalho, ... Scientific reports 11 (1), 6712, 2021 | 40 | 2021 |
Characterisation of a novel panel of polymorphic microsatellite loci for the liver fluke, Fasciola hepatica, using a next generation sequencing approach K Cwiklinski, K Allen, J LaCourse, DJ Williams, S Paterson, ... Infection, Genetics and Evolution 32, 298-304, 2015 | 36 | 2015 |