G-quadruplex structures mark human regulatory chromatin R Hänsel-Hertsch, D Beraldi, SV Lensing, G Marsico, K Zyner, A Parry, ... Nature genetics 48 (10), 1267-1272, 2016 | 868 | 2016 |
Targeting multiple effector pathways in pancreatic ductal adenocarcinoma with a G-quadruplex-binding small molecule C Marchetti, KG Zyner, SA Ohnmacht, M Robson, SM Haider, JP Morton, ... Journal of medicinal chemistry 61 (6), 2500-2517, 2018 | 148 | 2018 |
Quantifying receptor trafficking and colocalization with confocal microscopy JA Pike, IB Styles, JZ Rappoport, JK Heath Methods 115, 42-54, 2017 | 90 | 2017 |
Super-resolution microscopy: a comparison of commercially available options JA Thorley, J Pike, JZ Rappoport Fluorescence microscopy, 199-212, 2014 | 72 | 2014 |
Low-dose Btk inhibitors selectively block platelet activation by CLEC-2 PLR Nicolson, SH Nock, J Hinds, L Garcia-Quintanilla, CW Smith, ... Haematologica 106 (1), 208, 2020 | 67 | 2020 |
Topological data analysis quantifies biological nano-structure from single molecule localization microscopy JA Pike, AO Khan, C Pallini, SG Thomas, M Mund, J Ries, NS Poulter, ... Bioinformatics 36 (5), 1614-1621, 2020 | 63 | 2020 |
Flow studies on human GPVI-deficient blood under coagulating and noncoagulating conditions M Nagy, G Perrella, A Dalby, MF Becerra, L Garcia Quintanilla, JA Pike, ... Blood advances 4 (13), 2953-2961, 2020 | 57 | 2020 |
CRISPR-Cas9 mediated labelling allows for single molecule imaging and resolution AO Khan, VA Simms, JA Pike, SG Thomas, NV Morgan Scientific reports 7 (1), 8450, 2017 | 54 | 2017 |
Comparison of confocal and super-resolution reflectance imaging of metal oxide nanoparticles EJ Guggenheim, A Khan, J Pike, L Chang, I Lynch, JZ Rappoport PLoS One 11 (10), e0159980, 2016 | 53 | 2016 |
A framework for evaluating the performance of SMLM cluster analysis algorithms DJ Nieves, JA Pike, F Levet, DJ Williamson, M Baragilly, S Oloketuyi, ... Nature methods 20 (2), 259-267, 2023 | 50 | 2023 |
Platelet glycoprotein VI and C-type lectin-like receptor 2 deficiency accelerates wound healing by impairing vascular integrity in mice S Wichaiyo, S Lax, SJ Montague, Z Li, B Grygielska, JA Pike, EJ Haining, ... Haematologica 104 (8), 1648, 2019 | 44 | 2019 |
Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift Y Zhang, L Garcia-Ibanez, C Ulbricht, LSC Lok, JA Pike, J Mueller-Winkler, ... Nature Communications 13 (1), 2460, 2022 | 35 | 2022 |
Comparison of the GPVI inhibitors losartan and honokiol MB Onselaer, M Nagy, C Pallini, JA Pike, G Perrella, LG Quintanilla, ... Platelets 31 (2), 187-197, 2020 | 34 | 2020 |
An adaptable analysis workflow for characterization of platelet spreading and morphology JA Pike, VA Simms, CW Smith, NV Morgan, AO Khan, NS Poulter, ... Platelets 32 (1), 54-58, 2021 | 31 | 2021 |
Tetraspanin Tspan9 regulates platelet collagen receptor GPVI lateral diffusion and activation EJ Haining, AL Matthews, PJ Noy, HM Romanska, HJ Harris, J Pike, ... Platelets 28 (7), 629-642, 2017 | 30 | 2017 |
Fluorescence microscopy JA Thorley, J Pike, JZ Rappoport Super-Resolution Microscopy: A Comparison Of Commercially Available Options, 2014 | 29 | 2014 |
Post-translational polymodification of b1-tubulin regulates motor protein localization in platelet production and function AO Khan, A Slater, A Maclachlan, PLR Nicolson, JA Pike, JS Reyat, ... Haematologica 107 (1), 243, 2020 | 27 | 2020 |
Optimised insert design for improved single-molecule imaging and quantification through CRISPR-Cas9 mediated knock-in AO Khan, CW White, JA Pike, J Yule, A Slater, SJ Hill, NS Poulter, ... Scientific reports 9 (1), 14219, 2019 | 27 | 2019 |
Mathematical imaging methods for mitosis analysis in live-cell phase contrast microscopy JS Grah, JA Harrington, SB Koh, JA Pike, A Schreiner, M Burger, ... Methods 115, 91-99, 2017 | 26 | 2017 |
High-throughput platelet spreading analysis: a tool for the diagnosis of platelet-based bleeding disorders AO Khan, A Maclachlan, GC Lowe, PLR Nicolson, R Al Ghaithi, ... Haematologica 105 (3), e124, 2020 | 24 | 2020 |