Gary Mirams

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Katkıda bulunan yazarlar

David GavaghanProfessor of Computational Biology, University of Oxfordcs.ox.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Jonathan CooperUniversity College Londonucl.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Michael ClerxResearcher, University of Nottinghamnottingham.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Chon Lok LeiUniversity of Macauum.edu.mo üzerinde doğrulanmış e-posta adresine sahip
Pras PathmanathanFood and Drug Administrationfda.hhs.gov üzerinde doğrulanmış e-posta adresine sahip
Alexander G FletcherUniversity of Sheffieldsheffield.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Helen ByrneUniversity of Oxfordmaths.ox.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Joe Pitt-FrancisUniversity of Oxford, Department of Computer Sciencecs.ox.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Denis NobleEmeritus Professor of Cardiovascular Physiology, Oxford Universitydpag.ox.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Dominic G WhittakerGSKgsk.com üzerinde doğrulanmış e-posta adresine sahip
James OsborneUniversity of Melbourneunimelb.edu.au üzerinde doğrulanmış e-posta adresine sahip
Teun P. de BoerAssociate Professor, Department of Medical Physiology, University Medical Center Utrechtumcutrecht.nl üzerinde doğrulanmış e-posta adresine sahip
Mark R. DaviesesqLABSqtinformatics.com üzerinde doğrulanmış e-posta adresine sahip
Kylie A BeattieGlaxoSmithKlinegsk.com üzerinde doğrulanmış e-posta adresine sahip
Ross H. JohnstoneDPhil, University of Oxfordpm.me üzerinde doğrulanmış e-posta adresine sahip
Philip MainiProfessor of Mathematical Biologymaths.ox.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Blanca RodriguezUniversity of Oxfordcs.ox.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Miguel O. BernabeuProfessor of Computational Medicine, The University of Edinburghed.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Philip J MurrayDivision of Mathematics, University of Dundeemaths.ox.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Rémi BardenetCNRS, CRIStAL, Ecole Centrale Lille, Univ. Lille, Franceec-lille.fr üzerinde doğrulanmış e-posta adresine sahip

Takip et

Gary Mirams

Diğer adlarGary Richard Mirams

Centre for Mathematical Medicine & Biology, University of Nottingham

nottingham.ac.uk üzerinde doğrulanmış e-posta adresine sahip - Ana Sayfa

mathematical biology ion channels cardiac modelling cardiac electrophysiology safety pharmacology


Başlık Alıntılara göre sırala Yıla göre sırala Başlığa göre sırala	Alıntı yapanlar Alıntı yapanlar	Yıl
Chaste: an open source C++ library for computational physiology and biology GR Mirams, CJ Arthurs, MO Bernabeu, R Bordas, J Cooper, A Corrias, ... PLoS computational biology 9 (3), e1002970, 2013	519	2013
Simulation of multiple ion channel block provides improved early prediction of compounds’ clinical torsadogenic risk GR Mirams, Y Cui, A Sher, M Fink, J Cooper, BM Heath, NC McMahon, ... Cardiovascular research 91 (1), 53, 2011	347	2011
Chaste: a test-driven approach to software development for biological modelling J Pitt-Francis, P Pathmanathan, MO Bernabeu, R Bordas, J Cooper, ... Computer Physics Communications 180 (12), 2452-2471, 2009	313	2009
An integrative computational model for intestinal tissue renewal IMM Van Leeuwen, GR Mirams, A Walter, A Fletcher, P Murray, J Osborne, ... Cell proliferation 42 (5), 617-636, 2009	190	2009
Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models? RH Johnstone, ETY Chang, R Bardenet, TP De Boer, DJ Gavaghan, ... Journal of molecular and cellular cardiology 96, 49-62, 2016	171	2016
Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG MKB Jonsson, MA Vos, GR Mirams, G Duker, P Sartipy, TP de Boer, ... Journal of Molecular and Cellular Cardiology 52 (5), 998-1008, 2012	167	2012
Hydroxychloroquine reduces heart rate by modulating the hyperpolarization-activated current I f: Novel electrophysiological insights and therapeutic potential RA Capel, N Herring, M Kalla, A Yavari, GR Mirams, G Douglas, G Bub, ... Heart Rhythm 12 (10), 2186-2194, 2015	166	2015
Uncertainty and variability in computational and mathematical models of cardiac physiology GR Mirams, P Pathmanathan, RA Gray, P Challenor, RH Clayton The Journal of physiology 594 (23), 6833-6847, 2016	164	2016
Assessment of an in silico mechanistic model for proarrhythmia risk prediction under the CiPA initiative Z Li, WW Wu, J Sheng, PN Tran, M Wu, A Ranolph, RH Johnstone, ... Clinical Pharmacology & Therapeutics, 2018	155	2018
A hybrid approach to multi-scale modelling of cancer JM Osborne, A Walter, SK Kershaw, GR Mirams, AG Fletcher, ... Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2010	155	2010
A computational study of discrete mechanical tissue models P Pathmanathan, J Cooper, A Fletcher, G Mirams, P Murray, J Osborne, ... Physical biology 6 (3), 036001, 2009	148	2009
Computational assessment of drug‐induced effects on the electrocardiogram: from ion channel to body surface potentials N Zemzemi, MO Bernabeu, J Saiz, J Cooper, P Pathmanathan, ... British Journal of Pharmacology 168 (3), 718-733, 2012	132	2012
Application of cardiac electrophysiology simulations to pro‐arrhythmic safety testing GR Mirams, MR Davies, Y Cui, P Kohl, D Noble British Journal of Pharmacology 167 (5), 932-945, 2012	118	2012
Systems Toxicology: Real World Applications and Opportunities T Hartung, RE FitzGerald, P Jennings, GR Mirams, MC Peitsch, ... Chemical Research in Toxicology 30 (4), 870, 2017	115	2017
Calibration of ionic and cellular cardiac electrophysiology models DG Whittaker, M Clerx, CL Lei, DJ Christini, GR Mirams Wiley Interdisciplinary Reviews: Systems Biology and Medicine 12 (4), e1482, 2020	109	2020
Prediction of Thorough QT study results using action potential simulations based on ion channel screens GR Mirams, MR Davies, SJ Brough, MH Bridgland-Taylor, Y Cui, ... Journal of pharmacological and toxicological methods 70 (3), 246-254, 2014	104	2014
Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment RC Elkins, MR Davies, SJ Brough, DJ Gavaghan, Y Cui, N Abi-Gerges, ... Journal of pharmacological and toxicological methods 68 (1), 112-122, 2013	97	2013
Uncertainty quantification reveals the importance of data variability and experimental design considerations for in silico proarrhythmia risk assessment KC Chang, S Dutta, GR Mirams, KA Beattie, J Sheng, PN Tran, M Wu, ... Frontiers in physiology 8, 917, 2017	93	2017
General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico Strategy Z Li, GR Mirams, T Yoshinaga, BJ Ridder, X Han, JE Chen, ... Clinical Pharmacology & Therapeutics 107 (1), 102-111, 2020	86	2020
High resolution structural evidence suggests the sarcoplasmic reticulum forms microdomains with acidic stores (lysosomes) in the heart D Aston, RA Capel, KL Ford, HC Christian, GR Mirams, EA Rog-Zielinska, ... Scientific Reports 7, 40620, 2017	86	2017

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