Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma A Nijhuis, A Sikka, O Yogev, L Herendi, C Balcells, Y Ma, E Poon, ... Nature Communications 13 (1), 1380, 2022 | 52 | 2022 |
β2-adrenergic signalling promotes cell migration by upregulating expression of the metastasis-associated molecule LYPD3 M Gruet, D Cotton, C Coveney, DJ Boocock, S Wagner, L Komorowski, ... Biology 9 (2), 39, 2020 | 39 | 2020 |
Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma Y Xu, S Spear, Y Ma, MP Lorentzen, M Gruet, F McKinney, Y Xu, ... Cell Reports 42 (10), 2023 | 16 | 2023 |
Novel adrenergic receptor inhibitors and their inhibition of stress-induced metastasis of breast cancer D Cotton, A Miles, G Kinsella, M Gruet, C Garner, AG Pockley, R Rees, ... European Journal of Cancer 1 (69), S82-S83, 2016 | 1 | 2016 |
Abstract B096: Targeting RNA splicing factor RBM39 improves therapy responses in ovarian high-grade serous carcinoma Y Xu, S Spear, Y Ma, M Lorentzen, M Gruet, F McKinney, Y Xu, ... Cancer Research 84 (5_Supplement_2), B096-B096, 2024 | | 2024 |
RAS/PI3K pathway mutations sensitise epithelial ovarian cancer cells to a PARP/NAMPT inhibitor combination M Gruet, Y Xu, L An, Y Ma, C Balcells, K Tyson, S Spear, Y Xu, ... bioRxiv, 2024.10. 15.618473, 2024 | | 2024 |
Chemical tools for profiling the intracellular ADP-ribosylated proteome SD Draganov, MJ Gruet, D Conole, C Balcells, AP Siskos, HC Keun, ... RSC Chemical Biology, 2024 | | 2024 |