CAR T cells targeting B7-H3, a pan-cancer antigen, demonstrate potent preclinical activity against pediatric solid tumors and brain tumors RG Majzner, JL Theruvath, A Nellan, S Heitzeneder, Y Cui, CW Mount, ... Clinical Cancer Research 25 (8), 2560-2574, 2019 | 555 | 2019 |
Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling EW Weber, KR Parker, E Sotillo, RC Lynn, H Anbunathan, J Lattin, ... Science 372 (6537), eaba1786, 2021 | 479 | 2021 |
Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas CW Mount, RG Majzner, S Sundaresh, EP Arnold, M Kadapakkam, ... Nature medicine 24 (5), 572-579, 2018 | 474 | 2018 |
Tuning the antigen density requirement for CAR T-cell activity RG Majzner, SP Rietberg, E Sotillo, R Dong, VT Vachharajani, ... Cancer discovery 10 (5), 702-723, 2020 | 445 | 2020 |
Programming CAR-T cells to kill cancer L Labanieh, RG Majzner, CL Mackall Nature biomedical engineering 2 (6), 377-391, 2018 | 405 | 2018 |
CAR immune cells: design principles, resistance and the next generation L Labanieh, CL Mackall Nature 614 (7949), 635-648, 2023 | 343 | 2023 |
Nucleic acid aptamers in cancer research, diagnosis and therapy H Ma, J Liu, MM Ali, MAI Mahmood, L Labanieh, M Lu, SM Iqbal, Q Zhang, ... Chemical Society Reviews 44 (5), 1240-1256, 2015 | 264 | 2015 |
Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors J Theruvath, E Sotillo, CW Mount, CM Graef, A Delaidelli, S Heitzeneder, ... Nature medicine 26 (5), 712-719, 2020 | 237 | 2020 |
Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals Y Su, JR Walker, Y Park, TP Smith, LX Liu, MP Hall, L Labanieh, R Hurst, ... Nature methods 17 (8), 852-860, 2020 | 165 | 2020 |
Enhanced safety and efficacy of protease-regulated CAR-T cell receptors L Labanieh, RG Majzner, D Klysz, E Sotillo, CJ Fisher, JG Vilches-Moure, ... Cell 185 (10), 1745-1763. e22, 2022 | 159 | 2022 |
High-throughput screening technologies for enzyme engineering CK Longwell, L Labanieh, JR Cochran Current opinion in biotechnology 48, 196-202, 2017 | 148 | 2017 |
Co-opting signalling molecules enables logic-gated control of CAR T cells AM Tousley, MC Rotiroti, L Labanieh, LW Rysavy, WJ Kim, C Lareau, ... Nature 615 (7952), 507-516, 2023 | 147 | 2023 |
Delivery of CAR-T cells in a transient injectable stimulatory hydrogel niche improves treatment of solid tumors AK Grosskopf, L Labanieh, DD Klysz, GA Roth, P Xu, O Adebowale, ... Science Advances 8 (14), eabn8264, 2022 | 138 | 2022 |
Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system NH Kipniss, PCDP Dingal, TR Abbott, Y Gao, H Wang, AA Dominguez, ... Nature communications 8 (1), 2212, 2017 | 115 | 2017 |
Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery SH Chiou, D Tseng, A Reuben, V Mallajosyula, IS Molina, S Conley, ... Immunity 54 (3), 586-602. e8, 2021 | 109 | 2021 |
Encapsulated sensors and sensing systems for bioassays and diagnostics and methods for making and using them W Zhao, DK Kang, K Zhang, MM Ali, MA Eckert, F Li, E Gratton, ... | 107 | 2017 |
Rapid bacterial detection and antibiotic susceptibility testing in whole blood using one-step, high throughput blood digital PCR TJ Abram, H Cherukury, CY Ou, T Vu, M Toledano, Y Li, JT Grunwald, ... Lab on a Chip 20 (3), 477-489, 2020 | 104 | 2020 |
Digital quantification of miRNA directly in plasma using integrated comprehensive droplet digital detection K Zhang, DK Kang, MM Ali, L Liu, L Labanieh, M Lu, H Riazifar, ... Lab on a Chip 15 (21), 4217-4226, 2015 | 76 | 2015 |
Floating droplet array: An ultrahigh-throughput device for droplet trapping, real-time analysis and recovery L Labanieh, TN Nguyen, W Zhao, DK Kang Micromachines 6 (10), 1469-1482, 2015 | 66 | 2015 |
An engineered antibody binds a distinct epitope and is a potent inhibitor of murine and human VISTA N Mehta, S Maddineni, RL Kelly, RB Lee, SA Hunter, JL Silberstein, ... Scientific reports 10 (1), 15171, 2020 | 51 | 2020 |