Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations A Janssen, M Van Der Burg, K Szuhai, GJPL Kops, RH Medema Science 333 (6051), 1895-1898, 2011 | 685 | 2011 |
Heterochromatin: guardian of the genome A Janssen, SU Colmenares, GH Karpen Annual review of cell and developmental biology 34 (1), 265-288, 2018 | 462 | 2018 |
Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells A Janssen, GJPL Kops, RH Medema Proceedings of the National Academy of Sciences 106 (45), 19108-19113, 2009 | 375 | 2009 |
Kif15 cooperates with eg5 to promote bipolar spindle assembly ME Tanenbaum, L Macůrek, A Janssen, EF Geers, M Alvarez-Fernández, ... Current biology 19 (20), 1703-1711, 2009 | 326 | 2009 |
Mitosis as an anti-cancer target A Janssen, RH Medema Oncogene 30 (25), 2799-2809, 2011 | 138 | 2011 |
A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin A Janssen, GA Breuer, EK Brinkman, AI Van Der Meulen, SV Borden, ... Genes & development 30 (14), 1645-1657, 2016 | 129 | 2016 |
Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model ARR Maia, J de Man, U Boon, A Janssen, JY Song, M Omerzu, ... Annals of Oncology 26 (10), 2180-2192, 2015 | 127 | 2015 |
Genetic instability: tipping the balance A Janssen, RH Medema Oncogene 32 (38), 4459-4470, 2013 | 126 | 2013 |
Degree and site of chromosomal instability define its oncogenic potential WHM Hoevenaar, A Janssen, AI Quirindongo, H Ma, SJ Klaasen, ... Nature communications 11 (1), 1501, 2020 | 117 | 2020 |
Intravital FRET imaging of tumor cell viability and mitosis during chemotherapy A Janssen, E Beerling, R Medema, J van Rheenen PloS one 8 (5), e64029, 2013 | 69 | 2013 |
Timely double-strand break repair and pathway choice in pericentromeric heterochromatin depend on the histone demethylase dKDM4A A Janssen, SU Colmenares, T Lee, GH Karpen Genes & Development 33 (1-2), 103-115, 2019 | 54 | 2019 |
Molecular basis underlying resistance to Mps1/TTK inhibitors A Koch, A Maia, A Janssen, RH Medema Oncogene 35 (19), 2518-2528, 2016 | 51 | 2016 |
Targeting the mitotic checkpoint to kill tumor cells A Janssen, GJ Kops, RH Medema Hormones and Cancer 2, 113-116, 2011 | 45 | 2011 |
Entosis: aneuploidy by invasion A Janssen, RH Medema Nature cell biology 13 (3), 199-201, 2011 | 44 | 2011 |
The sound of silence: how silenced chromatin orchestrates the repair of double-strand breaks A Kendek, MR Wensveen, A Janssen Genes 12 (9), 1415, 2021 | 12 | 2021 |
The impact of chromatin on double-strand break repair: Imaging tools and discoveries MAE van Bueren, A Janssen DNA repair 133, 103592, 2024 | 6 | 2024 |
Stress mixes chromosomes A Janssen, RH Medema Nature 494 (7438), 439-441, 2013 | 5 | 2013 |
Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair MR Wensveen, AA Dixit, R van Schendel, A Kendek, JP Lambooij, ... Nature Communications 15 (1), 8984, 2024 | 1 | 2024 |
Varying recombination landscapes between individuals are driven by polymorphic transposable elements Y Huang, Y Gao, K Ly, L Lin, JP Lambooij, EG King, A Janssen, KHC Wei, ... bioRxiv, 2024 | | 2024 |
DNA Double-Strand Break Movement in Heterochromatin Depends on the Drosophila Histone Acetyltransferase Gcn5 A Kendek, A Sandron, JP Lambooij, SU Colmenares, P Sobrevals Alcaraz, ... bioRxiv, 2023.11. 30.569406, 2023 | | 2023 |