| Generation of new TRAIL mutants DR5-A and DR5-B with improved selectivity to death receptor 5 ME Gasparian, BV Chernyak, DA Dolgikh, AV Yagolovich, EN Popova, ... Apoptosis 14, 778-787, 2009 | 61 | 2009 |
| Overexpression and refolding of thioredoxin/TRAIL fusion from inclusion bodies and further purification of TRAIL after cleavage by enteropeptidase ME Gasparian, VG Ostapchenko, AV Yagolovich, IN Tsygannik, ... Biotechnology letters 29, 1567-1573, 2007 | 32 | 2007 |
| Death receptors DR4 and DR5 undergo spontaneous and ligand-mediated endocytosis and recycling regardless of the sensitivity of cancer cells to TRAIL AA Artykov, AV Yagolovich, DA Dolgikh, MP Kirpichnikov, DB Trushina, ... Frontiers in cell and developmental biology 9, 733688, 2021 | 28 | 2021 |
| Genetically Modified DR5-Specific TRAIL Variant DR5-B Revealed Dual Antitumor and Protumoral Effect in Colon Cancer Xenografts and an Improved Pharmacokinetic Profile AV Yagolovich, AA Artykov, TA Karmakova, MS Vorontsova, AA Pankratov, ... Translational Oncology 13 (4), 100762, 2020 | 14 | 2020 |
| A new efficient method for production of recombinant antitumor cytokine TRAIL and its receptor-selective variant DR5-B AV Yagolovich, AA Artykov, DA Dolgikh, MP Kirpichnikov, ME Gasparian Biochemistry (Moscow) 84, 627-636, 2019 | 14 | 2019 |
| Mutations enhancing selectivity of antitumor cytokine TRAIL to DR5 receptor increase its cytotoxicity against tumor cells ME Gasparian, ML Bychkov, AV Yagolovich, DA Dolgikh, MP Kirpichnikov Biochemistry (Moscow) 80, 1080-1091, 2015 | 13 | 2015 |
| Amphiphilic Poly(N-vinylpyrrolidone) Nanoparticles Conjugated with DR5-Specific Antitumor Cytokine DR5-B for Targeted Delivery to Cancer Cells A Yagolovich, A Kuskov, P Kulikov, L Kurbanova, D Bagrov, A Artykov, ... Pharmaceutics 13 (9), 1413, 2021 | 10 | 2021 |
| Doxorubicin-loaded polyelectrolyte multilayer capsules modified with antitumor DR5-specific TRAIL variant for targeted drug delivery to tumor cells A Gileva, D Trushina, A Yagolovich, M Gasparian, L Kurbanova, I Smirnov, ... Nanomaterials 13 (5), 902, 2023 | 9 | 2023 |
| Dr5-selective trail variant dr5-b functionalized with tumor-penetrating irgd peptide for enhanced antitumor activity against glioblastoma AV Yagolovich, AA Isakova, AA Artykov, YV Vorontsova, DV Mazur, ... International Journal of Molecular Sciences 23 (20), 12687, 2022 | 9 | 2022 |
| Optimized heterologous expression and efficient purification of a new TRAIL-based antitumor fusion protein SRH–DR5-B with dual VEGFR2 and DR5 receptor specificity AV Yagolovich, AA Artykov, AA Isakova, YV Vorontsova, DA Dolgikh, ... International Journal of Molecular Sciences 23 (11), 5860, 2022 | 8 | 2022 |
| Cytoskeleton inhibitors combined with TRAIL induce apoptosis in HeLa carcinoma cells overexpressing antiapoptotic protein Bcl-2 ME Gasparian, LV Domnina, OY Ivanova, DS Izyumov, AY Lomakin, ... Biochemistry (Moscow) 73, 358-362, 2008 | 8 | 2008 |
| Toxicity Evaluation and Controlled-Release of Curcumin-Loaded Amphiphilic Poly-N-vinylpyrrolidone Nanoparticles: In Vitro and In Vivo Models AL Luss, DV Bagrov, AV Yagolovich, EV Kukovyakina, II Khan, ... Pharmaceutics 16 (1), 8, 2023 | 7 | 2023 |
| The effect of cisplatin on cytotoxicity of anticancer cytokine TRAIL and its receptor-selective mutant variant DR5-B1 ME Gasparian, ML Bychkov, AV Yagolovich, MP Kirpichnikov, DA Dolgikh Doklady Biochemistry and Biophysics 477, 385-388, 2017 | 7 | 2017 |
| Recent advances in the development of nanodelivery systems targeting the TRAIL death receptor pathway AV Yagolovich, ME Gasparian, DA Dolgikh Pharmaceutics 15 (2), 515, 2023 | 6 | 2023 |
| Assessment of the effects of amphiphilic poly (N‑vinylpyrrolidone) nanoparticles loaded with bortezomib on glioblastoma cell lines and zebrafish embryos AV Yagolovich, AN Kuskov, PP Kulikov, DV Bagrov, PA Petrova, ... Biomedical Reports 20 (3), 37, 2024 | 4 | 2024 |
| Dual targeting of DR5 and VEGFR2 molecular pathways by multivalent fusion protein significantly suppresses tumor growth and angiogenesis AA Isakova, AA Artykov, EA Plotnikova, GV Trunova, VА Khokhlova, ... International Journal of Biological Macromolecules 255, 128096, 2024 | 4 | 2024 |
| Application of an autoinduction strategy to optimize the heterologous production of an antitumor bispecific fusion protein based on the TRAIL receptor-selective mutant variant … A Isakova, A Artykov, Y Vorontsova, D Dolgikh, M Kirpichnikov, ... Molecular Biotechnology 65 (4), 581-589, 2023 | 3 | 2023 |
| Enhancing tumor targeted therapy: the role of iRGD peptide in advanced drug delivery systems D Nikitovic, E Kukovyakina, A Berdiaki, A Tzanakakis, A Luss, E Vlaskina, ... Cancers 16 (22), 3768, 2024 | 2 | 2024 |
| Death Receptors DR4 and DR5 Undergo Spontaneous and Ligand-Mediated Endocytosis and Recycling Regardless of the Sensitivity of Cancer Cells to TRAIL (vol 9, 733688, 2021) AA Artykov, AV Yagolovich, DA Dolgikh, MP Kirpichnikov, DB Trushina, ... FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 9, 2022 | 2 | 2022 |
| Antitumor Cytokine DR5-B-Conjugated Polymeric Poly (N-vinylpyrrolidone) Nanoparticles with Enhanced Cytotoxicity in Human Colon Carcinoma 3D Cell Spheroids A Yagolovich, A Kuskov, P Kulikov, L Kurbanova, A Gileva, E Markvicheva Mater. Proc 7 (8), 2021 | 1 | 2021 |
