| Early goal-directed therapy in the treatment of severe sepsis and septic shock MT E Rivers, B Nguyen, S Havstad, J Ressler, A Muzzin, B Knoblich, E Peterson N Engl J Med 345 (19), 1368-77, 2001 | 13663* | 2001 |
| Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 8e JE Tintinalli, JS Stapczynski, OJ Ma, DM Yealy, GD Meckler, DM Cline McGraw Hill Education, 2016 | 2456 | 2016 |
| Early lactate clearance is associated with improved outcome in severe sepsis and septic shock HB Nguyen, EP Rivers, BP Knoblich, G Jacobsen, A Muzzin, JA Ressler, ... Critical care medicine 32 (8), 1637-1642, 2004 | 1888 | 2004 |
| Factors associated with death in critically ill patients with coronavirus disease 2019 in the US S Gupta, SS Hayek, W Wang, L Chan, KS Mathews, ML Melamed, ... JAMA internal medicine 180 (11), 1436-1447, 2020 | 1033 | 2020 |
| Implementation of a bundle of quality indicators for the early management of severe sepsis and septic shock is associated with decreased mortality HB Nguyen, SW Corbett, R Steele, J Banta, RT Clark, SR Hayes, ... Critical care medicine 35 (4), 1105-1112, 2007 | 781 | 2007 |
| Severe sepsis and septic shock: review of the literature and emergency department management guidelines HB Nguyen, EP Rivers, FM Abrahamian, GJ Moran, E Abraham, ... Annals of emergency medicine 48 (1), 54. e1, 2006 | 557 | 2006 |
| Association between early treatment with tocilizumab and mortality among critically ill patients with COVID-19 S Gupta, W Wang, SS Hayek, L Chan, KS Mathews, ML Melamed, ... JAMA internal medicine 181 (1), 41-51, 2021 | 553 | 2021 |
| Validation of cell-cycle arrest biomarkers for acute kidney injury using clinical adjudication A Bihorac, LS Chawla, AD Shaw, A Al-Khafaji, DL Davison, GE DeMuth, ... American journal of respiratory and critical care medicine 189 (8), 932-939, 2014 | 530 | 2014 |
| Early goal-directed therapy in severe sepsis and septic shock revisited: concepts, controversies, and contemporary findings RM Otero, HB Nguyen, DT Huang, DF Gaieski, M Goyal, KJ Gunnerson, ... Chest 130 (5), 1579-1595, 2006 | 449 | 2006 |
| A prospective, multicenter derivation of a biomarker panel to assess risk of organ dysfunction, shock, and death in emergency department patients with suspected sepsis NI Shapiro, S Trzeciak, JE Hollander, R Birkhahn, R Otero, TM Osborn, ... Critical care medicine 37 (1), 96-104, 2009 | 355 | 2009 |
| AKI treated with renal replacement therapy in critically ill patients with COVID-19 S Gupta, SG Coca, L Chan, ML Melamed, SK Brenner, SS Hayek, ... Journal of the American Society of Nephrology 32 (1), 161-176, 2021 | 334 | 2021 |
| Early lactate clearance is associated with biomarkers of inflammation, coagulation, apoptosis, organ dysfunction and mortality in severe sepsis and septic shock HB Nguyen, M Loomba, JJ Yang, G Jacobsen, K Shah, RM Otero, ... Journal of inflammation 7, 1-11, 2010 | 329 | 2010 |
| Characteristics and outcomes of individuals with pre-existing kidney disease and COVID-19 admitted to intensive care units in the United States JE Flythe, MM Assimon, MJ Tugman, EH Chang, S Gupta, J Shah, ... American Journal of Kidney Diseases 77 (2), 190-203. e1, 2021 | 263 | 2021 |
| Central venous-arterial carbon dioxide difference as an indicator of cardiac index J Cuschieri, EP Rivers, MW Donnino, M Katilius, G Jacobsen, HB Nguyen, ... Intensive care medicine 31, 818-822, 2005 | 263 | 2005 |
| Critical care in the emergency department a physiologic assessment and outcome evaluation HB Nguyen, EP Rivers, S Havstad, B Knoblich, JA Ressler, AM Muzzin, ... Academic Emergency Medicine 7 (12), 1354-1361, 2000 | 250 | 2000 |
| Early goal-directed therapy in severe sepsis and septic shock: insights and comparisons to ProCESS, ProMISe, and ARISE HB Nguyen, AK Jaehne, N Jayaprakash, MW Semler, S Hegab, ... Critical Care 20, 1-16, 2016 | 249 | 2016 |
| The diagnostic accuracy of plasma neutrophil gelatinase–associated lipocalin in the prediction of acute kidney injury in emergency department patients with suspected sepsis NI Shapiro, S Trzeciak, JE Hollander, R Birkhahn, R Otero, TM Osborn, ... Annals of emergency medicine 56 (1), 52-59. e1, 2010 | 175 | 2010 |
| Outcome effectiveness of the severe sepsis resuscitation bundle with addition of lactate clearance as a bundle item: a multi-national evaluation HB Nguyen, WS Kuan, M Batech, P Shrikhande, M Mahadevan, CH Li, ... Critical care 15, 1-10, 2011 | 173 | 2011 |
| Sepsis in the 21st century: recent definitions and therapeutic advances HB Nguyen, D Smith The American journal of emergency medicine 25 (5), 564-571, 2007 | 134 | 2007 |
| Superior accuracy of mid-regional proadrenomedullin for mortality prediction in sepsis with varying levels of illness severity D Andaluz-Ojeda, HB Nguyen, N Meunier-Beillard, R Cicuéndez, ... Annals of intensive care 7, 1-8, 2017 | 127 | 2017 |
