In vivo delivery of CRISPR-Cas9 using lipid nanoparticles enables antithrombin gene editing for sustainable hemophilia A and B therapy JP Han, MJ Kim, BS Choi, JH Lee, GS Lee, M Jeong, Y Lee, EA Kim, ... Science advances 8 (3), eabj6901, 2022 | 137 | 2022 |
Immunogenicity of lipid nanoparticles and its impact on the efficacy of mRNA vaccines and therapeutics Y Lee, M Jeong, J Park, H Jung, H Lee Experimental & Molecular Medicine 55 (10), 2085-2096, 2023 | 107 | 2023 |
Lipid nanoparticles (LNPs) for in vivo RNA delivery and their breakthrough technology for future applications M Jeong, Y Lee, J Park, H Jung, H Lee Advanced drug delivery reviews, 114990, 2023 | 83 | 2023 |
In vivo genome editing for hemophilia B therapy by the combination of rebalancing and therapeutic gene knockin using a viral and non-viral vector JH Lee, JP Han, DW Song, GS Lee, BS Choi, MJ Kim, Y Lee, S Kim, ... Molecular Therapy-Nucleic Acids 32, 161-172, 2023 | 19 | 2023 |
Novel piperazine‐based ionizable lipid nanoparticles allow the repeated dose of mRNA to fibrotic lungs with improved potency and safety M Kim, M Jeong, G Lee, Y Lee, J Park, H Jung, S Im, JS Yang, K Kim, ... Bioengineering & Translational Medicine 8 (6), e10556, 2023 | 16 | 2023 |
In vivo genome editing using 244-cis LNPs and low-dose AAV achieves therapeutic threshold in hemophilia A mice JP Han, Y Lee, JH Lee, HY Chung, GS Lee, YR Nam, M Choi, KS Moon, ... Molecular Therapy-Nucleic Acids 34, 2023 | 8 | 2023 |
Innate immune responses against mRNA vaccine promote cellular immunity through IFN-β at the injection site S Kim, JH Jeon, M Kim, Y Lee, YH Hwang, M Park, CH Li, T Lee, JA Lee, ... Nature Communications 15 (1), 7226, 2024 | 4 | 2024 |
Development of Lipid Nanoparticle Formulation for the Repeated Administration of mRNA Therapeutics Y Lee, M Jeong, G Lee, J Park, H Jung, S Im, H Lee Biomaterials Research 28, 0017, 2024 | 2 | 2024 |
Development of lipid nanoparticle formulation for intramuscular administration of mRNA vaccine against respiratory syncytial virus E Jang, Y Lee, E Ko, M Jeong, J Chang, H Lee Journal of Pharmaceutical Investigation, 1-13, 2025 | | 2025 |
Engineered lipid nanoparticles enable therapeutic gene silencing of GTSE1 for the treatment of liver fibrosis M Jeong, S Shin, G Lee, Y Lee, SB Park, J Kang, YS Lee, W Seo, H Lee Journal of Controlled Release 374, 337-348, 2024 | | 2024 |