Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity C Angermueller, SJ Clark, HJ Lee, IC Macaulay, MJ Teng, TX Hu, ... Nature methods 13 (3), 229-232, 2016 | 773 | 2016 |
scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells SJ Clark, R Argelaguet, CA Kapourani, TM Stubbs, HJ Lee, ... Nature communications 9 (1), 1-9, 2018 | 652 | 2018 |
Joint Profiling Of Chromatin Accessibility, DNA Methylation And Transcription In Single Cells SJ Clark, R Argelaguet, CA Kapourani, TM Stubbs, HJ Lee, F Krueger, ... bioRxiv, 138685, 2017 | 652* | 2017 |
Multi-omics profiling of mouse gastrulation at single-cell resolution R Argelaguet, SJ Clark, H Mohammed, LC Stapel, C Krueger, ... Nature 576 (7787), 487-491, 2019 | 423 | 2019 |
Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity SJ Clark, HJ Lee, SA Smallwood, G Kelsey, W Reik Genome biology 17 (1), 1-10, 2016 | 332 | 2016 |
Genome-wide base-resolution mapping of DNA methylation in single cells using single-cell bisulfite sequencing (scBS-seq) SJ Clark, SA Smallwood, HJ Lee, F Krueger, W Reik, G Kelsey Nature protocols 12 (3), 534-547, 2017 | 256 | 2017 |
Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in mouse muscle stem cells I Hernando-Herraez, B Evano, T Stubbs, PH Commere, MJ Bonder, ... Nature communications 10 (1), 1-11, 2019 | 202 | 2019 |
Genome-wide bisulfite sequencing in zygotes identifies demethylation targets and maps the contribution of TET3 oxidation JR Peat, W Dean, SJ Clark, F Krueger, SA Smallwood, G Ficz, JK Kim, ... Cell reports 9 (6), 1990-2000, 2014 | 139 | 2014 |
Continuous histone replacement by Hira is essential for normal transcriptional regulation and de novo DNA methylation during mouse oogenesis B Nashun, PWS Hill, SA Smallwood, G Dharmalingam, R Amouroux, ... Molecular cell 60 (4), 611-625, 2015 | 125 | 2015 |
Association of sirtuin 1 (SIRT1) gene SNPs and transcript expression levels with severe obesity SJ Clark, M Falchi, B Olsson, P Jacobson, S Cauchi, B Balkau, M Marre, ... Obesity 20 (1), 178-185, 2012 | 93 | 2012 |
Genome-scale oscillations in DNA methylation during exit from pluripotency S Rulands, HJ Lee, SJ Clark, C Angermueller, SA Smallwood, F Krueger, ... Cell systems 7 (1), 63-76. e12, 2018 | 89 | 2018 |
Spatial profiling of early primate gastrulation in utero S Bergmann, CA Penfold, E Slatery, D Siriwardena, C Drummer, S Clark, ... Nature 609 (7925), 136-143, 2022 | 86 | 2022 |
Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity SM Linker, L Urban, SJ Clark, M Chhatriwala, S Amatya, DJ McCarthy, ... Genome biology 20 (1), 1-14, 2019 | 68 | 2019 |
The role of ZFP57 and additional KRAB-zinc finger proteins in the maintenance of human imprinted methylation and multi-locus imprinting disturbances A Monteagudo-Sánchez, JR Hernandez Mora, C Simon, A Burton, ... Nucleic acids research 48 (20), 11394-11407, 2020 | 48 | 2020 |
Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses J Rodríguez-Ubreva, A Arutyunyan, MJ Bonder, L Del Pino-Molina, ... Nature communications 13 (1), 1779, 2022 | 40 | 2022 |
Increased transcriptome variation and localised DNA methylation changes in oocytes from aged mice revealed by parallel single‐cell analysis J Castillo‐Fernandez, E Herrera‐Puerta, H Demond, SJ Clark, CW Hanna, ... Aging cell 19 (12), e13278, 2020 | 40 | 2020 |
Enhancer-associated H3K4 methylation safeguards in vitro germline competence T Bleckwehl, G Crispatzu, K Schaaf, P Respuela, M Bartusel, L Benson, ... Nature Communications 12 (1), 5771, 2021 | 38 | 2021 |
Decoding gene regulation in the mouse embryo using single-cell multi-omics R Argelaguet, T Lohoff, JG Li, A Nakhuda, D Drage, F Krueger, L Velten, ... BioRxiv, 2022.06. 15.496239, 2022 | 36 | 2022 |
Single-cell multi-omics profiling links dynamic DNA methylation to cell fate decisions during mouse early organogenesis SJ Clark, R Argelaguet, T Lohoff, F Krueger, D Drage, B Göttgens, ... Genome biology 23 (1), 202, 2022 | 22 | 2022 |
Conserved and unique transcriptional features of pharyngeal arches in the skate (Leucoraja erinacea) and evolution of the jaw C Hirschberger, VA Sleight, KE Criswell, SJ Clark, JA Gillis Molecular Biology and Evolution 38 (10), 4187-4204, 2021 | 21 | 2021 |