Two endoplasmic reticulum PDI peroxidases increase the efficiency of the use of peroxide during disulfide bond formation VD Nguyen, MJ Saaranen, AR Karala, AK Lappi, L Wang, IB Raykhel, ... Journal of molecular biology 406 (3), 503-515, 2011 | 329 | 2011 |
Protein disulfide–isomerase, a folding catalyst and a redox-regulated chaperone L Wang, X Wang, C Wang Free Radical Biology and Medicine 83, 305-313, 2015 | 181 | 2015 |
Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7 J Fang, J Yang, X Wu, G Zhang, T Li, X Wang, H Zhang, C Wang, GH Liu, ... Aging cell 17 (4), e12765, 2018 | 162 | 2018 |
Reconstitution of human Ero1-Lα/protein-disulfide isomerase oxidative folding pathway in vitro: position-dependent differences in role between the a and a′ domains of protein … L Wang, S Li, A Sidhu, L Zhu, Y Liang, RB Freedman, C Wang Journal of Biological Chemistry 284 (1), 199-206, 2009 | 157 | 2009 |
Human protein-disulfide isomerase is a redox-regulated chaperone activated by oxidation of domain a′ C Wang, J Yu, L Huo, L Wang, W Feng, C Wang Journal of Biological Chemistry 287 (2), 1139-1149, 2012 | 155 | 2012 |
Homocysteine causes vascular endothelial dysfunction by disrupting endoplasmic reticulum redox homeostasis X Wu, L Zhang, Y Miao, J Yang, X Wang, C Wang, J Feng, L Wang Redox biology 20, 46-59, 2019 | 144 | 2019 |
Glutathione peroxidase 7 utilizes hydrogen peroxide generated by Ero1α to promote oxidative protein folding L Wang, L Zhang, Y Niu, R Sitia, C Wang Antioxidants & redox signaling 20 (4), 545-556, 2014 | 143 | 2014 |
Autophagy impairment mediated by S-nitrosation of ATG4B leads to neurotoxicity in response to hyperglycemia Y Li, Y Zhang, L Wang, P Wang, Y Xue, X Li, X Qiao, X Zhang, T Xu, G Liu, ... Autophagy 13 (7), 1145-1160, 2017 | 102 | 2017 |
Phosphorylation switches protein disulfide isomerase activity to maintain proteostasis and attenuate ER stress J Yu, T Li, Y Liu, X Wang, J Zhang, X Wang, G Shi, J Lou, L Wang, ... The EMBO journal 39 (10), e103841, 2020 | 88 | 2020 |
Crystal structure of human ERp44 shows a dynamic functional modulation by its carboxy‐terminal tail L Wang, L Wang, S Vavassori, S Li, H Ke, T Anelli, M Degano, R Ronzoni, ... EMBO reports 9 (7), 642-647, 2008 | 86 | 2008 |
Plasticity of human protein disulfide isomerase: evidence for mobility around the X-linker region and its functional significance C Wang, S Chen, X Wang, L Wang, AK Wallis, RB Freedman, C Wang Journal of Biological Chemistry 285 (35), 26788-26797, 2010 | 79 | 2010 |
A solvatochromic fluorescent probe reveals polarity heterogeneity upon protein aggregation in cells W Wan, L Zeng, W Jin, X Chen, D Shen, Y Huang, M Wang, Y Bai, H Lyu, ... Angewandte Chemie 133 (49), 26069-26075, 2021 | 74 | 2021 |
The endoplasmic reticulum sulfhydryl oxidase Ero1β drives efficient oxidative protein folding with loose regulation L Wang, L Zhu, C Wang Biochemical Journal 434 (1), 113-121, 2011 | 66 | 2011 |
Pathological hydrogen peroxide triggers the fibrillization of wild-type SOD1 via sulfenic acid modification of Cys-111 WC Xu, JZ Liang, C Li, ZX He, HY Yuan, BY Huang, XL Liu, B Tang, ... Cell death & disease 9 (2), 67, 2018 | 63 | 2018 |
Different interaction modes for protein-disulfide isomerase (PDI) as an efficient regulator and a specific substrate of endoplasmic reticulum oxidoreductin-1α (Ero1α) L Zhang, Y Niu, L Zhu, J Fang, L Wang, C Wang Journal of Biological Chemistry 289 (45), 31188-31199, 2014 | 60 | 2014 |
Secretory kinase Fam20C tunes endoplasmic reticulum redox state via phosphorylation of Ero1α J Zhang, Q Zhu, X Wang, J Yu, X Chen, J Wang, X Wang, J Xiao, C Wang, ... The EMBO Journal 37 (14), e98699, 2018 | 47 | 2018 |
Oxidative protein folding fidelity and redoxtasis in the endoplasmic reticulum L Wang, C Wang Trends in biochemical sciences 48 (1), 40-52, 2023 | 46 | 2023 |
Targeting the functional interplay between endoplasmic reticulum oxidoreductin-1α and protein disulfide isomerase suppresses the progression of cervical cancer Y Zhang, T Li, L Zhang, F Shangguan, G Shi, X Wu, Y Cui, X Wang, Y Liu, ... EBioMedicine 41, 408-419, 2019 | 46 | 2019 |
Domain a’of protein disulfide isomerase plays key role in inhibiting α-synuclein fibril formation H Cheng, L Wang, C Wang Cell Stress and Chaperones 15 (4), 415-421, 2010 | 44 | 2010 |
SARS-CoV-2 ORF8 reshapes the ER through forming mixed disulfides with ER oxidoreductases P Liu, X Wang, Y Sun, H Zhao, F Cheng, J Wang, F Yang, J Hu, H Zhang, ... Redox Biology 54, 102388, 2022 | 30 | 2022 |