Takip et
William Ralvenius
William Ralvenius
MIT, Picower Institute of Learining and Memory
pharma.uzh.ch üzerinde doğrulanmış e-posta adresine sahip
Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
Modeling Alzheimer’s disease with iPSC-derived brain cells
J Penney, WT Ralvenius, LH Tsai
Molecular psychiatry 25 (1), 148-167, 2020
4502020
Targeted ablation, silencing, and activation establish glycinergic dorsal horn neurons as key components of a spinal gate for pain and itch
E Foster, H Wildner, L Tudeau, S Haueter, WT Ralvenius, M Jegen, ...
Neuron 85 (6), 1289-1304, 2015
3922015
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes
JW Blanchard, LA Akay, J Davila-Velderrain, D von Maydell, H Mathys, ...
Nature 611 (7937), 769-779, 2022
2882022
APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia
G Sienski, P Narayan, JM Bonner, N Kory, S Boland, AA Arczewska, ...
Science translational medicine 13 (583), eaaz4564, 2021
2612021
Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype
WT Ralvenius, D Benke, MA Acuna, U Rudolph, HU Zeilhofer
Nature communications 6 (1), 6803, 2015
1252015
Acetaminophen relieves inflammatory pain through CB1 cannabinoid receptors in the rostral ventromedial medulla
PP Klinger-Gratz, WT Ralvenius, E Neumann, A Kato, R Nyilas, Z Lele, ...
Journal of Neuroscience 38 (2), 322-334, 2018
892018
Antihyperalgesia by α2-GABAA receptors occurs via a genuine spinal action and does not involve supraspinal sites
J Paul, GE Yévenes, D Benke, AD Lio, WT Ralvenius, R Witschi, ...
Neuropsychopharmacology 39 (2), 477-487, 2014
652014
Phosphorylation state–dependent modulation of spinal glycine receptors alleviates inflammatory pain
MA Acuña, GE Yévenes, WT Ralvenius, D Benke, A Di Lio, CO Lara, ...
The Journal of clinical investigation 126 (7), 2547-2560, 2016
632016
Restoring the spinal pain gate: GABAA receptors as targets for novel analgesics
HU Zeilhofer, WT Ralvenius, MA Acuña
Advances in pharmacology 73, 71-96, 2015
602015
Localization and production of peptide endocannabinoids in the rodent CNS and adrenal medulla
SC Hofer, WT Ralvenius, MS Gachet, JM Fritschy, HU Zeilhofer, J Gertsch
Neuropharmacology 98, 78-89, 2015
562015
A virus-like particle-based anti-nerve growth factor vaccine reduces inflammatory hyperalgesia: potential long-term therapy for chronic pain
TA Röhn, WT Ralvenius, J Paul, P Borter, M Hernandez, R Witschi, ...
The Journal of Immunology 186 (3), 1769-1780, 2011
352011
Itch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors
WT Ralvenius, E Neumann, M Pagani, MA Acuña, H Wildner, D Benke, ...
Nature communications 9 (1), 1-15, 2018
342018
The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesia
WT Ralvenius, MA Acuña, D Benke, A Matthey, Y Daali, U Rudolph, ...
Neuropharmacology 109, 366-375, 2016
332016
Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration
N Morshed, WT Ralvenius, A Nott, LA Watson, FH Rodriguez, LA Akay, ...
Molecular Systems Biology 16 (12), e9819, 2020
262020
GABAA receptor subtypes in the mouse brain: regional mapping and diazepam receptor occupancy by in vivo [18F] flumazenil PET
AM Herde, D Benke, WT Ralvenius, L Mu, R Schibli, HU Zeilhofer, ...
Neuroimage 150, 279-291, 2017
262017
Nanoparticle‐mediated delivery of Anti‐PU. 1 siRNA via localized intracisternal administration reduces neuroinflammation
WT Ralvenius, JL Andresen, MM Huston, J Penney, JM Bonner, ...
Advanced Materials 36 (8), 2309225, 2024
252024
The positive allosteric GABAB receptor modulator rac-BHFF enhances baclofen-mediated analgesia in neuropathic mice
K Zemoura, WT Ralvenius, P Malherbe, D Benke
Neuropharmacology 108, 172-178, 2016
182016
iPSC‐derived microglia carrying the TREM2 R47H/+ mutation are proinflammatory and promote synapse loss
J Penney, WT Ralvenius, A Loon, O Cerit, V Dileep, B Milo, PC Pao, ...
Glia 72 (2), 452-469, 2024
172024
APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia. Sci Transl Med 13: eaaz4564
G Sienski, P Narayan, JM Bonner, N Kory, S Boland, AA Arczewska, ...
142021
Hö sli, L
E Foster, H Wildner, L Tudeau, S Haueter, WT Ralvenius, M Jegen, ...
Haenraets, K., Ghanem, A., et al, 1289-1304, 2015
142015
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