Intratumoral heterogeneity in cancer progression and response to immunotherapy I Vitale, E Shema, S Loi, L Galluzzi Nature medicine 27 (2), 212-224, 2021 | 583 | 2021 |
Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks L Moyal, Y Lerenthal, M Gana-Weisz, G Mass, S So, SY Wang, B Eppink, ... Molecular cell 41 (5), 529-542, 2011 | 450 | 2011 |
Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells N Minsky, E Shema, Y Field, M Schuster, E Segal, M Oren Nature cell biology 10 (4), 483-488, 2008 | 433 | 2008 |
The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression E Shema, I Tirosh, Y Aylon, J Huang, C Ye, N Moskovits, N Raver-Shapira, ... Genes & development 22 (19), 2664-2676, 2008 | 315 | 2008 |
RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation G Fuchs, E Shema, R Vesterman, E Kotler, Z Wolchinsky, S Wilder, ... Molecular cell 46 (5), 662-673, 2012 | 223 | 2012 |
Single-cell and single-molecule epigenomics to uncover genome regulation at unprecedented resolution E Shema, BE Bernstein, JD Buenrostro Nature genetics 51 (1), 19-25, 2019 | 191 | 2019 |
CDK9 directs H2B monoubiquitination and controls replication‐dependent histone mRNA 3′‐end processing J Pirngruber, A Shchebet, L Schreiber, E Shema, N Minsky, RD Chapman, ... EMBO reports 10 (8), 894-900, 2009 | 184 | 2009 |
RNF20 links histone H2B ubiquitylation with inflammation and inflammation-associated cancer O Tarcic, IS Pateras, T Cooks, E Shema, J Kanterman, H Ashkenazi, ... Cell reports 14 (6), 1462-1476, 2016 | 152 | 2016 |
Single-molecule decoding of combinatorially modified nucleosomes E Shema, D Jones, N Shoresh, L Donohue, O Ram, BE Bernstein Science 352 (6286), 717-721, 2016 | 150 | 2016 |
Two phases of mitogenic signaling unveil roles for p53 and EGR1 in elimination of inconsistent growth signals Y Zwang, A Sas-Chen, Y Drier, T Shay, R Avraham, M Lauriola, E Shema, ... Molecular cell 42 (4), 524-535, 2011 | 119 | 2011 |
Coupled evolution of transcription and mRNA degradation M Dori-Bachash, E Shema, I Tirosh PLoS biology 9 (7), e1001106, 2011 | 118 | 2011 |
RNF20 inhibits TFIIS-facilitated transcriptional elongation to suppress pro-oncogenic gene expression E Shema, J Kim, RG Roeder, M Oren Molecular cell 42 (4), 477-488, 2011 | 107 | 2011 |
Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription E Shema-Yaacoby, M Nikolov, M Haj-Yahya, P Siman, E Allemand, ... Cell reports 4 (3), 601-608, 2013 | 98 | 2013 |
RNF20–RNF40: A ubiquitin-driven link between gene expression and the DNA damage response Y Shiloh, E Shema, L Moyal, M Oren FEBS letters 585 (18), 2795-2802, 2011 | 87 | 2011 |
Multiplexed, single-molecule, epigenetic analysis of plasma-isolated nucleosomes for cancer diagnostics V Fedyuk, N Erez, N Furth, O Beresh, E Andreishcheva, A Shinde, ... Nature biotechnology 41 (2), 212-221, 2023 | 55 | 2023 |
N‐Methylation of isopeptide bond as a strategy to resist deubiquitinases M Haj‐Yahya, N Eltarteer, S Ohayon, E Shema, E Kotler, M Oren, A Brik Angewandte Chemie 46 (124), 11703-11707, 2012 | 51 | 2012 |
Single-cell epigenetic analysis reveals principles of chromatin states in H3. 3-K27M gliomas N Harpaz, T Mittelman, O Beresh, O Griess, N Furth, TM Salame, R Oren, ... Molecular cell 82 (14), 2696-2713. e9, 2022 | 32 | 2022 |
H3-K27M-mutant nucleosomes interact with MLL1 to shape the glioma epigenetic landscape N Furth, D Algranati, B Dassa, O Beresh, V Fedyuk, N Morris, LH Kasper, ... Cell Reports 39 (7), 2022 | 29 | 2022 |
Functional Conservation of the Yeast and Arabidopsis RAD54-Like Genes M Klutstein, H Shaked, A Sherman, N Avivi-Ragolsky, E Shema, ... Genetics 178 (4), 2389-2397, 2008 | 29 | 2008 |
SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity D Sheban, T Shani, R Maor, A Aguilera-Castrejon, N Mor, B Oldak, ... Molecular cell 82 (1), 106-122. e9, 2022 | 23 | 2022 |