Identification of the von Hippel-Lindau disease tumor suppressor gene F Latif, K Tory, J Gnarra, M Yao, FM Duh, ML Orcutt, T Stackhouse, ... Science 260 (5112), 1317-1320, 1993 | 3609 | 1993 |
Mutations of the VHL tumour suppressor gene in renal carcinoma JR Gnarra, K Tory, Y Weng, L Schmidt, MH Wei, H Li, F Latif, S Liu, ... Nature genetics 7 (1), 85-90, 1994 | 2102 | 1994 |
Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. JG Herman, F Latif, Y Weng, MI Lerman, B Zbar, S Liu, D Samid, DS Duan, ... Proceedings of the National Academy of Sciences 91 (21), 9700-9704, 1994 | 1991 | 1994 |
Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia P Sarraf, RC Frederich, EM Turner, G Ma, NT Jaskowiak, DJ Rivet, ... Journal of Experimental Medicine 185 (1), 171-176, 1997 | 1073 | 1997 |
Germline mutations in the von Hippel–Lindau disease tumor suppressor gene: correlations with phenotype F Chen, T Kishida, M Yao, T Hustad, D Glavac, M Dean, JR Gnarra, ... Human mutation 5 (1), 66-75, 1995 | 663 | 1995 |
Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene. JR Gnarra, S Zhou, MJ Merrill, JR Wagner, A Krumm, E Papavassiliou, ... Proceedings of the National Academy of Sciences 93 (20), 10589-10594, 1996 | 653 | 1996 |
Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice JR Gnarra, JM Ward, FD Porter, JR Wagner, DE Devor, A Grinberg, ... Proceedings of the National Academy of Sciences 94 (17), 9102-9107, 1997 | 455 | 1997 |
A microdissection technique for archival DNA analysis of specific cell populations in lesions< 1 mm in size Z Zhuang, P Bertheau, MR Emmert-Buck, LA Liotta, J Gnarra, ... The American journal of pathology 146 (3), 620, 1995 | 384 | 1995 |
Clinical and genetic characterization of pheochromocytoma in von Hippel-Lindau families: comparison with sporadic pheochromocytoma gives insight into natural history of … MM WALTHER, R REITER, HR KEISER, PL CHOYKE, D VENZON, ... The Journal of urology 162 (3), 659-664, 1999 | 303 | 1999 |
Role of transforming growth factor-α in von Hippel– Lindau (VHL)−/− clear cell renal carcinoma cell proliferation: A possible mechanism coupling VHL tumor … N De Paulsen, A Brychzy, MC Fournier, RD Klausner, JR Gnarra, A Pause, ... Proceedings of the National Academy of Sciences 98 (4), 1387-1392, 2001 | 285 | 2001 |
The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cells S Koochekpour, M Jeffers, PH Wang, C Gong, GA Taylor, LM Roessler, ... Molecular and cellular biology 19 (9), 5902-5912, 1999 | 240 | 1999 |
Allelic deletions of the VHL gene detected in multiple microscopic clear cell renal lesions in von Hippel-Lindau disease patients IA Lubensky, JR Gnarra, P Bertheau, MM Walther, WM Linehan, Z Zhuang The American journal of pathology 149 (6), 2089, 1996 | 235 | 1996 |
Identification of an actin binding region and a protein kinase C phosphorylation site on human fascin S Ono, Y Yamakita, S Yamashiro, PT Matsudaira, JR Gnarra, T Obinata, ... Journal of Biological Chemistry 272 (4), 2527-2533, 1997 | 229 | 1997 |
von Hippel-Lindau gene deletion detected in the stromal cell component of a cerebellar hemangioblastoma associated with von Hippel-Lindau disease AO Vortmeyer, JR Gnarra, MR Emmert-Buck, D Katz, WM Linehan, ... Human pathology 28 (5), 540-543, 1997 | 216 | 1997 |
Loss of HLA haplotype and B locus down-regulation in melanoma cell lines. FM Marincola, P Shamamian, RB Alexander, JR Gnarra, RL Turetskaya, ... Journal of immunology (Baltimore, Md.: 1950) 153 (3), 1225-1237, 1994 | 202 | 1994 |
Characterization of the VHL tumor suppressor gene product: localization, complex formation, and the effect of natural inactivating mutations. DR Duan, JS Humphrey, DY Chen, Y Weng, J Sukegawa, S Lee, ... Proceedings of the National Academy of Sciences 92 (14), 6459-6463, 1995 | 194 | 1995 |
Nuclear/cytoplasmic localization of the von Hippel-Lindau tumor suppressor gene product is determined by cell density. S Lee, DY Chen, JS Humphrey, JR Gnarra, WM Linehan, RD Klausner Proceedings of the National Academy of Sciences 93 (5), 1770-1775, 1996 | 189 | 1996 |
Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth FA Mack, WK Rathmell, AM Arsham, J Gnarra, B Keith, MC Simon Cancer cell 3 (1), 75-88, 2003 | 187 | 2003 |
Comparative genomic analysis of tumors: detection of DNA losses and amplification. NA Lisitsyn, NM Lisitsina, G Dalbagni, P Barker, CA Sanchez, J Gnarra, ... Proceedings of the National Academy of Sciences 92 (1), 151-155, 1995 | 180 | 1995 |
Expression of Pax-2 in Human Renal Cell Carcinoma and Growth Inhibition by Antisense Oligonucleotides JR Gnarra, GR Dressler Cancer research 55 (18), 4092-4098, 1995 | 177 | 1995 |