Nrf2 controls iron homoeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin PJ Lim, TL Duarte, J Arezes, D Garcia-Santos, A Hamdi, SR Pasricha, ... Nature Metabolism 1 (5), 519-531, 2019 | 129 | 2019 |
Bone morphogenetic protein 2 controls iron homeostasis in mice independent of Bmp6 S Canali, CY Wang, KB Zumbrennen‐Bullough, A Bayer, JL Babitt American journal of hematology 92 (11), 1204-1213, 2017 | 127 | 2017 |
MyD88: At the heart of inflammatory signaling and cardiovascular disease AL Bayer, P Alcaide Journal of molecular and cellular cardiology 161, 75-85, 2021 | 68 | 2021 |
Endothelial STING controls T cell transmigration in an IFNI-dependent manner M Anastasiou, GA Newton, K Kaur, FJ Carrillo-Salinas, SA Smolgovsky, ... JCI insight 6 (15), e149346, 2021 | 38 | 2021 |
Ablation of Hepatocyte Smad1, Smad5, and Smad8 Causes Severe Tissue Iron Loading and Liver Fibrosis in Mice CY Wang, X Xiao, A Bayer, Y Xu, S Dev, S Canali, AV Nair, R Masia, ... Hepatology 70 (6), 1986-2002, 2019 | 38 | 2019 |
Iron, erythropoietin, and inflammation regulate hepcidin in Bmp2‐deficient mice, but serum iron fails to induce hepcidin in Bmp6‐deficient mice CY Wang, S Canali, A Bayer, S Dev, A Agarwal, JL Babitt American journal of hematology 94 (2), 240-248, 2019 | 34 | 2019 |
Endothelial bone morphogenetic protein 2 (Bmp2) knockout exacerbates hemochromatosis in homeostatic iron regulator (Hfe) knockout mice but not Bmp6 knockout mice X Xiao, S Dev, S Canali, A Bayer, Y Xu, A Agarwal, CY Wang, JL Babitt Hepatology 72 (2), 642-655, 2020 | 31 | 2020 |
Impaired T cell IRE1α/XBP1 signaling directs inflammation in experimental heart failure with preserved ejection fraction S Smolgovsky, AL Bayer, K Kaur, E Sanders, M Aronovitz, ME Filipp, ... The Journal of clinical investigation 133 (24), 2023 | 20 | 2023 |
T-cell MyD88 is a novel regulator of cardiac fibrosis through modulation of T-cell activation AL Bayer, S Smolgovsky, N Ngwenyama, A Hernández-Martínez, K Kaur, ... Circulation research 133 (5), 412-429, 2023 | 15 | 2023 |
Endothelial Bmp2 knockout exacerbates hemochromatosis in Hfe knockout mice but not Bmp6 knockout mice X Xiao, S Dev, S Canali, A Bayer, Y Xu, A Agarwal, CY Wang, JL Babitt Hepatology (Baltimore, Md.) 72 (2), 642, 2020 | 13 | 2020 |
AKT1 is required for a complete Palbociclib-Induced Senescence phenotype in BRAF-V600E-Driven Human Melanoma AL Bayer, J Pietruska, J Farrell, S McRee, P Alcaide, PW Hinds Cancers 14 (3), 572, 2022 | 9 | 2022 |
Cytotoxic T cells drive doxorubicin-induced cardiac fibrosis and systolic dysfunction AL Bayer, MA Zambrano, S Smolgovsky, ZL Robbe, A Ariza, K Kaur, ... Nature cardiovascular research 3 (8), 970-986, 2024 | 5 | 2024 |
A novel therapeutic approach using CXCR3 blockade to treat immune checkpoint inhibitor-mediated myocarditis YV Huang, D Lee, Y Sun, H Chou, B Xu, Z Lin, C Branche, A Bayer, ... BioRxiv, 2024.01. 30.576279, 2024 | 4 | 2024 |
AKT2 loss impairs BRAF-mutant melanoma metastasis SK McRee, AL Bayer, J Pietruska, PN Tsichlis, PW Hinds Cancers 15 (20), 4958, 2023 | 3 | 2023 |
Doxorubicin Induces a Cytotoxic T-cell Inflammatory Response That Contributes to Cardiac Fibrosis and Systolic Dysfunction A Bayer, M Zambrano, S Smolgovsky, Z Robbe, A Ariza, K kaur, ... Circulation 150 (Suppl_1), A4118086-A4118086, 2024 | | 2024 |
Novel Therapeutic Approach Targeting CXCR3 to Treat Immunotherapy Myocarditis YV Huang, Y Sun, H Chou, N Wagner, MR Vitale, AL Bayer, B Xu, D Lee, ... Circulation Research, 2024 | | 2024 |
Abstract We075: Stimulator of Interferon Genes (STING) Regulates T Cell Fate in Cardiometabolic Heart Failure with Preserved Ejection Fraction (HFpEF) S Smolgovsky, A Bayer, R Emig, Z Magri, mark aronovitz, K kaur, ... Circulation Research 135 (Suppl_1), AWe075-AWe075, 2024 | | 2024 |
Abstract Tu084: Endothelial Cell STING contributes to Systolic Dysfunction by modulating cardiomyocyte hypertrophy and capillary density in pressure overload-induced heart failure E Sanders, N Wagner, A Bayer, S Smolgovsky, B Theall, mark aronovitz, ... Circulation Research 135 (Suppl_1), ATu084-ATu084, 2024 | | 2024 |
Abstract Tu096: The Aryl Hydrocarbon Receptor Agonist, L-Kynurenine, Modulates Cardiac Fibroblast Activation and Antigen Presentation B Theall, S Smolgovsky, A Bayer, E Sanders, M Zambrano, Z Robbe, ... Circulation Research 135 (Suppl_1), ATu096-ATu096, 2024 | | 2024 |
Deletion of MyD88 in T Cells Improves Antitumor Activity in Melanoma AL Bayer, D Padilla-Rolon, S Smolgovsky, PW Hinds, P Alcaide The American Journal of Pathology 194 (6), 1007-1019, 2024 | | 2024 |