Evolutionary selection and constraint on human knee chondrocyte regulation impacts osteoarthritis risk D Richard, Z Liu, J Cao, AM Kiapour, J Willen, S Yarlagadda, E Jagoda, ... Cell 181 (2), 362-381. e28, 2020 | 106 | 2020 |
The active grandparent hypothesis: Physical activity and the evolution of extended human healthspans and lifespans DE Lieberman, TM Kistner, D Richard, IM Lee, AL Baggish Proceedings of the National Academy of Sciences 118 (50), e2107621118, 2021 | 71 | 2021 |
Identification of novel loci associated with hip shape: a meta‐analysis of genomewide association studies DA Baird, DS Evans, FK Kamanu, JS Gregory, FR Saunders, ... Journal of bone and mineral research 34 (2), 241-251, 2019 | 67 | 2019 |
Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses A Banerjee, N El-Sayes, P Budylowski, RA Jacob, D Richard, H Maan, ... IScience 24 (5), 2021 | 51 | 2021 |
Epigenetic profiling of growth plate chondrocytes sheds insight into regulatory genetic variation influencing height M Guo, Z Liu, J Willen, CP Shaw, D Richard, E Jagoda, AC Doxey, ... elife 6, e29329, 2017 | 38 | 2017 |
Joint disease-specificity at the regulatory base-pair level P Muthuirulan, D Zhao, M Young, D Richard, Z Liu, A Emami, G Portilla, ... Nature Communications 12 (1), 4161, 2021 | 29 | 2021 |
Rainbow trout exposed to benzo [a] pyrene yields conserved microRNA binding sites in DNA methyltransferases across 500 million years of evolution C Kuc, DJ Richard, S Johnson, L Bragg, MR Servos, AC Doxey, PM Craig Scientific reports 7 (1), 16843, 2017 | 25 | 2017 |
Lineage-specific differences and regulatory networks governing human chondrocyte development D Richard, S Pregizer, D Venkatasubramanian, RM Raftery, ... Elife 12, e79925, 2023 | 17 | 2023 |
The developmental impacts of natural selection on human pelvic morphology M Young, D Richard, M Grabowski, BM Auerbach, BS De Bakker, ... Science advances 8 (33), eabq4884, 2022 | 17 | 2022 |
GWAS meta-analysis followed by Mendelian randomization revealed potential control mechanisms for circulating α-Klotho levels I Gergei, J Zheng, TFM Andlauer, V Brandenburg, N Mirza-Schreiber, ... Human molecular genetics 31 (5), 792-802, 2022 | 14 | 2022 |
Lineage-specific mutational clustering in protein structures predicts evolutionary shifts in function J Adams, MJ Mansfield, DJ Richard, AC Doxey Bioinformatics 33 (9), 1338-1345, 2017 | 14 | 2017 |
Regulatory dissection of the severe COVID-19 risk locus introgressed by Neanderthals E Jagoda, D Marnetto, G Senevirathne, V Gonzalez, K Baid, F Montinaro, ... elife 12, e71235, 2023 | 13 | 2023 |
Epigenetics as a mediator of genetic risk in osteoarthritis: role during development, homeostasis, aging, and disease progression D Richard, TD Capellini, BO Diekman American Journal of Physiology-Cell Physiology 324 (5), C1078-C1088, 2023 | 12 | 2023 |
Fructose regulates the pentose phosphate pathway and induces an inflammatory and resolution phenotype in Kupffer cells M Lodge, G Scheidemantle, VR Adams, MA Cottam, D Richard, D Breuer, ... Scientific Reports 14 (1), 4020, 2024 | 10 | 2024 |
Intronic regulation of SARS-CoV-2 receptor (ACE2) expression mediated by immune signaling and oxidative stress pathways D Richard, P Muthuirulan, J Aguiar, AC Doxey, A Banerjee, K Mossman, ... Iscience 25 (7), 2022 | 6 | 2022 |
Shifting epigenetic contexts influence regulatory variation and disease risk D Richard, TD Capellini Aging (Albany NY) 13 (12), 15699, 2021 | 6 | 2021 |
Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses. iScience 24, 102477 A Banerjee, N El-Sayes, P Budylowski, RA Jacob, D Richard, H Maan, ... | 5 | 2021 |
Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses. iScience. 2021; 24: 102477 A Banerjee, N El-Sayes, P Budylowski, RA Jacob, D Richard, H Maan, ... PubMed https://doi. org/10.1016/j. isci, 2021 | 5 | 2021 |
Disagreement on foundational principles of biological aging VN Gladyshev, B Anderson, H Barlit, B Barré, S Beck, B Behrouz, ... PNAS nexus 3 (12), pgae499, 2024 | 4 | 2024 |
Functional genomics of human skeletal development and the patterning of height heritability D Richard, P Muthuirulan, M Young, L Yengo, S Vedantam, E Marouli, ... Cell 188 (1), 15-32. e24, 2025 | 3 | 2025 |