Targeting ABL-IRE1α signaling spares ER-stressed pancreatic β cells to reverse autoimmune diabetes S Morita, SA Villalta, HC Feldman, AC Register, W Rosenthal, ... Cell metabolism 25 (4), 883-897. e8, 2017 | 234 | 2017 |
Structural and functional analysis of the allosteric inhibition of IRE1α with ATP-competitive ligands HC Feldman, M Tong, L Wang, R Meza-Acevedo, TA Gobillot, I Lebedev, ... ACS chemical biology 11 (8), 2195-2205, 2016 | 101 | 2016 |
Selective inhibitors of SARM1 targeting an allosteric cysteine in the autoregulatory ARM domain HC Feldman, E Merlini, C Guijas, KE DeMeester, E Njomen, EM Kozina, ... Proceedings of the National Academy of Sciences 119 (35), e2208457119, 2022 | 51 | 2022 |
Development of a chemical toolset for studying the paralog-specific function of IRE1 HC Feldman, VN Vidadala, ZE Potter, FR Papa, BJ Backes, DJ Maly ACS chemical biology 14 (12), 2595-2605, 2019 | 25 | 2019 |
ATP-competitive partial antagonists of the IRE1α RNase segregate outputs of the UPR HC Feldman, R Ghosh, VC Auyeung, JL Mueller, JH Kim, ZE Potter, ... Nature chemical biology 17 (11), 1148-1156, 2021 | 10 | 2021 |
Sexually dimorphic effects of monoacylglycerol lipase inhibitor MJN110 on stress‐related behaviour and drinking in Marchigian Sardinian alcohol‐preferring rats V Vozella, B Cruz, HC Feldman, R Bullard, PC Bianchi, LA Natividad, ... British Journal of Pharmacology 180 (24), 3130-3145, 2023 | 3 | 2023 |
Profiling the dual enzymatic activities of the serine/threonine kinase ire1α HC Feldman, DJ Maly Cancer Gene Networks, 233-242, 2017 | 1 | 2017 |
MONOACYLGLYCEROL LIPASE (MAGL) MEDIATES ANXIETY AND IRRITABILITY-LIKE BEHAVIORS IN A SEX-DEPENDENT MANNER IN MARCHIGIAN SARDINIAN ALCOHOL-PREFERRING (MSP) RATS V Vozella, H Feldman, B Cruz, LA Natividad, EP Zorrilla, R Ciccocioppo, ... ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 45, 147A-147A, 2021 | | 2021 |
Pharmacological Modulation and Functional Characterization of the Protein Kinase-Endoribonuclease IRE1α HC Feldman | | 2019 |
Allosteric Modulation of the Kinase/RNase IRE1a by Small Molecules and Scaffolding Kinases H Feldman, S Morita, F Papa, DJ Maly PROTEIN SCIENCE 26, 73-74, 2017 | | 2017 |