MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis H Alborzinia, AF Flórez, S Kreth, LM Brückner, U Yildiz, M Gartlgruber, ... Nature cancer 3 (4), 471-485, 2022 | 132 | 2022 |
PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma M Bleu, S Gaulis, R Lopes, K Sprouffske, V Apfel, S Holwerda, ... Nature communications 10 (1), 3739, 2019 | 64 | 2019 |
High-throughput functional characterization of protein phosphorylation sites in yeast C Viéitez, BP Busby, D Ochoa, A Mateus, D Memon, M Galardini, U Yildiz, ... Nature Biotechnology 40 (3), 382-390, 2022 | 37 | 2022 |
Systematic dissection of transcriptional regulatory networks by genome-scale and single-cell CRISPR screens R Lopes, K Sprouffske, C Sheng, ECH Uijttewaal, AE Wesdorp, ... Science advances 7 (27), eabf5733, 2021 | 31 | 2021 |
LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma H Alborzinia, Z Chen, U Yildiz, FP Freitas, FCE Vogel, JP Varga, J Batani, ... EMBO Molecular Medicine 15 (8), e18014, 2023 | 29 | 2023 |
Selenocysteine metabolism is a targetable vulnerability in MYCN-amplified cancers H Alborzinia, Z Chen, U Yildiz, FP Freitas, FCE Vogel, J Varga, J Batani, ... bioRxiv, 2022.05. 17.492172, 2022 | 7 | 2022 |
PRDX6 contributes to selenocysteine metabolism and ferroptosis resistance Z Chen, A Inague, K Kaushal, G Fazeli, D Schilling, TNX da Silva, ... Molecular Cell 84 (23), 4645-4659. e9, 2024 | 5 | 2024 |
Low level of antioxidant capacity biomarkers but not target overexpression predicts vulnerability to ROS-inducing drugs J Samarin, P Fabrowski, R Kurilov, H Nuskova, J Hummel-Eisenbeiss, ... Redox Biology 62, 102639, 2023 | 5 | 2023 |
Histone H3. 3 lysine 9 and 27 control repressive chromatin at cryptic enhancers and bivalent promoters M Trovato, D Bunina, U Yildiz, N Fernandez-Novel Marx, M Uckelmann, ... Nature communications 15 (1), 7557, 2024 | 3 | 2024 |
Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease S Lobato-Moreno, U Yildiz, A Claringbould, NH Servaas, EP Vlachou, ... bioRxiv, 2023.12. 26.573253, 2023 | 2 | 2023 |
nNOS-derived NO modulates force production and iNO-derived NO the excitability in C2C12-derived 3D tissue engineering skeletal muscle via different NO … M Mosqueira, LM Scheid, D Kiemel, T Richardt, M Rheinberger, D Ollech, ... Frontiers in Physiology 13, 946682, 2022 | 2 | 2022 |
Functional phenotyping of genomic variants using multiomic scDNA-scRNA-seq D Lindenhofer, JR Bauman, JA Hawkins, D Fitzgerald, U Yildiz, ... bioRxiv, 2024.05. 31.596895, 2024 | 1 | 2024 |
HIPSD&R-seq enables scalable genomic copy number and transcriptome profiling O Lazareva, JP Mallm, M Simovic-Lorenz, G Philippos, P Sant, U Parekh, ... bioRxiv, 2023.10. 09.561487, 2023 | 1 | 2023 |
Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1–HER3 signaling R Würth, E Donato, LL Michel, M Saini, L Becker, T Cheytan, D Doncevic, ... Nature cancer, 1-19, 2025 | | 2025 |
Functional dissection of schizophrenia risk genes using single-cell CRISPR screens U Yildiz | | 2025 |
HIPSD&R-seq enables scalable genomic copy number and transcriptome profiling J Otoničar, O Lazareva, JP Mallm, M Simovic-Lorenz, G Philippos, P Sant, ... Genome biology 25 (1), 1-22, 2024 | | 2024 |
LRP8-Mediated Selenocysteine Uptake is a Targetable Vulnerability in MYCN-Amplified Cancers H Alborzinia, Z Chen, U Yildiz, FP Freitas, FCE Vogel, JP Varga, J Batani, ... | | |
MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis U Yildiz, M Gartlgruber, DI Odoni, G Poschet, K Garbowicz, C Shao, ... | | |