CRISPR inversion of CTCF sites alters genome topology and enhancer/promoter function Y Guo, Q Xu, D Canzio, J Shou, J Li, DU Gorkin, I Jung, H Wu, Y Zhai, ... Cell 162 (4), 900-910, 2015 | 1071 | 2015 |
Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly D Canzio, EY Chang, S Shankar, KM Kuchenbecker, MD Simon, ... Molecular cell 41 (1), 67-81, 2011 | 393 | 2011 |
Structural basis of silencing: Sir3 BAH domain in complex with a nucleosome at 3.0 Å resolution KJ Armache, JD Garlick, D Canzio, GJ Narlikar, RE Kingston Science 334 (6058), 977-982, 2011 | 318 | 2011 |
Mechanisms of functional promiscuity by HP1 proteins D Canzio, A Larson, GJ Narlikar Trends in cell biology 24 (6), 377-386, 2014 | 217 | 2014 |
A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly D Canzio, M Liao, N Naber, E Pate, A Larson, S Wu, DB Marina, JF Garcia, ... Nature 496 (7445), 377-381, 2013 | 205 | 2013 |
Antisense lncRNA transcription mediates DNA demethylation to drive stochastic protocadherin α promoter choice D Canzio, CL Nwakeze, A Horta, SM Rajkumar, EL Coffey, EE Duffy, ... Cell 177 (3), 639-653. e15, 2019 | 153 | 2019 |
Writing, reading, and translating the clustered protocadherin cell surface recognition code for neural circuit assembly G Mountoufaris, D Canzio, CL Nwakeze, WV Chen, T Maniatis Annual review of cell and developmental biology 34 (1), 471-493, 2018 | 96 | 2018 |
The loss of TBK1 kinase activity in motor neurons or in all cell types differentially impacts ALS disease progression in SOD1 mice V Gerbino, E Kaunga, J Ye, D Canzio, S O’Keeffe, ND Rudnick, ... Neuron 106 (5), 789-805. e5, 2020 | 88 | 2020 |
The generation of a protocadherin cell-surface recognition code for neural circuit assembly D Canzio, T Maniatis Current opinion in neurobiology 59, 213-220, 2019 | 64 | 2019 |
Clustered protocadherins methylation alterations in cancer AF Vega-Benedetti, E Loi, L Moi, S Blois, A Fadda, M Antonelli, A Arcella, ... Clinical epigenetics 11, 1-20, 2019 | 48 | 2019 |
WAPL functions as a rheostat of Protocadherin isoform diversity that controls neural wiring L Kiefer, A Chiosso, J Langen, A Buckley, S Gaudin, SM Rajkumar, ... Science 380 (6651), eadf8440, 2023 | 29 | 2023 |
STL-seq reveals pause-release and termination kinetics for promoter-proximal paused RNA polymerase II transcripts JT Zimmer, NA Rosa-Mercado, D Canzio, JA Steitz, MD Simon Molecular cell 81 (21), 4398-4412. e7, 2021 | 28 | 2021 |
Solid phase chemistry to covalently and reversibly capture thiolated RNA EE Duffy, D Canzio, T Maniatis, MD Simon Nucleic acids research 46 (14), 6996-7005, 2018 | 25 | 2018 |
DNA sequence recognition by Hoechst 33258 conjugates of hairpin pyrrole/imidazole polyamides BJ Correa, D Canzio, AL Kahane, PM Reddy, TC Bruice Bioorganic & medicinal chemistry letters 16 (14), 3745-3750, 2006 | 17 | 2006 |
Incorporation of positively charged ribonucleic guanidine linkages into oligodeoxyribonucleotides: Development of potent antisense agents M Park, D Canzio, TC Bruice Bioorganic & medicinal chemistry letters 18 (7), 2377-2384, 2008 | 15 | 2008 |
Tuning cohesin trajectories enables differential readout of the Pcdhα cluster across neurons L Kiefer, S Gaudin, SM Rajkumar, GIF Servito, J Langen, MH Mui, ... Science 385 (6707), eadm9802, 2024 | 3 | 2024 |
Cohesin erases genomic-proximity biases to drive stochastic Protocadherin expression for proper neural wiring L Kiefer, GIF Servito, SM Rajkumar, J Langen, A Chiosso, A Buckley, ... bioRxiv, 2022.03. 09.483674, 2022 | 2 | 2022 |
Antisense lncRNA transcription drives stochastic Protocadherin α promoter choice D Canzio, CL Nwakeze, A Horta, SM Rajkumar, EL Coffey, EE Duffy, ... bioRxiv, 360206, 2018 | 2 | 2018 |
Cohesin erases genomic-proximity biases to drive stochastic Protocadherin expression for proper neural wiring D Canzio, L Kiefer, GI Servito, S Rajkumar, J Langen, A Chiosso, ... | | 2022 |
Abstract IA23: Functional and structural studies of HP1 heterochromatin D Canzio, M Liang, N Naber, A Larson, D Marina, J Garcia, H Madhani, ... Cancer Research 73 (13_Supplement), IA23-IA23, 2013 | | 2013 |