| A dihydropyridine receptor α 1s loop region critical for skeletal muscle contraction is intrinsically unstructured and binds to a SPRY domain of the type 1 ryanodine receptor Y Cui, HS Tae, NC Norris, Y Karunasekara, P Pouliquin, PG Board, ... The international journal of biochemistry & cell biology 41 (3), 677-686, 2009 | 64 | 2009 |
| Structure–Activity Studies of Cysteine‐Rich α‐Conotoxins that Inhibit High‐Voltage‐Activated Calcium Channels via GABAB Receptor Activation Reveal a Minimal … BB Carstens, G Berecki, JT Daniel, HS Lee, KAV Jackson, HS Tae, ... Angewandte Chemie International Edition 55 (15), 4692-4696, 2016 | 62 | 2016 |
| Medicinal chemistry, pharmacology, and therapeutic potential of α-conotoxins antagonizing the α9α10 nicotinic acetylcholine receptor X Li, HS Tae, Y Chu, T Jiang, DJ Adams, R Yu Pharmacology & Therapeutics 222, 107792, 2021 | 44 | 2021 |
| α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors J Wan, JX Huang, I Vetter, M Mobli, J Lawson, HS Tae, N Abraham, ... Journal of the American Chemical Society 137 (9), 3209-3212, 2015 | 39 | 2015 |
| Ubiquitous SPRY domains and their role in the skeletal type ryanodine receptor HS Tae, MG Casarotto, AF Dulhunty European Biophysics Journal 39, 51-59, 2009 | 38 | 2009 |
| Functional variants in HCN4 and CACNA1H may contribute to genetic generalized epilepsy F Becker, CA Reid, K Hallmann, HS Tae, AM Phillips, G Teodorescu, ... Epilepsia Open 2 (3), 334-342, 2017 | 34 | 2017 |
| Structure–Activity Studies Reveal the Molecular Basis for GABAB-Receptor Mediated Inhibition of High Voltage-Activated Calcium Channels by α-Conotoxin Vc1.1 M Sadeghi, BB Carstens, BP Callaghan, JT Daniel, HS Tae, T O’Donnell, ... ACS chemical biology 13 (6), 1577-1587, 2018 | 32 | 2018 |
| Molecular Determinants Conferring the Stoichiometric-Dependent Activity of α-Conotoxins at the Human α9α10 Nicotinic Acetylcholine Receptor Subtype R Yu, HS Tae, N Tabassum, J Shi, T Jiang, DJ Adams Journal of medicinal chemistry 61 (10), 4628-4634, 2018 | 31 | 2018 |
| Gabapentin modulates HCN4 channel voltage-dependence HS Tae, KM Smith, AM Phillips, KA Boyle, M Li, IC Forster, RJ Hatch, ... Frontiers in pharmacology 8, 554, 2017 | 30 | 2017 |
| α‐Conotoxins active at α3‐containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition H Cuny, R Yu, HS Tae, SN Kompella, DJ Adams British journal of pharmacology 175 (11), 1855-1868, 2018 | 29 | 2018 |
| Interaction of synthetic human SLURP-1 with the nicotinic acetylcholine receptors T Durek, IV Shelukhina, HS Tae, P Thongyoo, EN Spirova, ... Scientific Reports 7 (1), 16606, 2017 | 27 | 2017 |
| Key structural determinants in the agonist binding loops of human β2 and β4 nicotinic acetylcholine receptor subunits contribute to α3β4 subtype selectivity of α-conotoxins H Cuny, SN Kompella, HS Tae, R Yu, DJ Adams Journal of Biological Chemistry 291 (45), 23779-23792, 2016 | 26 | 2016 |
| Coronaridine congeners decrease neuropathic pain in mice and inhibit α9α10 nicotinic acetylcholine receptors and CaV2. 2 channels HR Arias, HS Tae, L Micheli, A Yousuf, C Ghelardini, DJ Adams, ... Neuropharmacology 175, 108194, 2020 | 24 | 2020 |
| Dimerization of α-Conotoxins as a Strategy to Enhance the Inhibition of the Human α7 and α9α10 Nicotinic Acetylcholine Receptors J Liang, HS Tae, X Xu, T Jiang, DJ Adams, R Yu Journal of Medicinal Chemistry 63 (6), 2974-2985, 2020 | 24 | 2020 |
| Molecular recognition of the disordered dihydropyridine receptor II–III loop by a conserved spry domain of the type 1 ryanodine receptor HS Tae, NC Norris, Y Cui, Y Karunasekara, PG Board, AF Dulhunty, ... Clinical and Experimental Pharmacology and Physiology 36 (3), 346-349, 2009 | 24 | 2009 |
| Small-molecule mimicry hunting strategy in the imperial cone snail, Conus imperialis JP Torres, Z Lin, M Watkins, PF Salcedo, RP Baskin, S Elhabian, ... Science Advances 7 (11), eabf2704, 2021 | 23 | 2021 |
| Targeting of N-Type Calcium Channels via GABAB-Receptor Activation by α-Conotoxin Vc1.1 Variants Displaying Improved Analgesic Activity F Cai, N Xu, Z Liu, R Ding, S Yu, M Dong, S Wang, J Shen, HS Tae, ... Journal of Medicinal Chemistry 61 (22), 10198-10205, 2018 | 21 | 2018 |
| Identification of a Novel O-Conotoxin Reveals an Unusual and Potent Inhibitor of the Human α9α10 Nicotinic Acetylcholine Receptor S Jiang, HS Tae, S Xu, X Shao, DJ Adams, C Wang Marine Drugs 15 (6), 170, 2017 | 21 | 2017 |
| α-Conotoxin Vc1. 1 Structure–Activity Relationship at the Human α9α10 Nicotinic Acetylcholine Receptor Investigated by Minimal Side Chain Replacement X Chu, HS Tae, Q Xu, T Jiang, DJ Adams, R Yu ACS chemical neuroscience 10 (10), 4328-4336, 2019 | 20 | 2019 |
| Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer X Wu, YH Huang, Q Kaas, PJ Harvey, CK Wang, HS Tae, DJ Adams, ... Journal of Biological Chemistry 292 (41), 17101-17112, 2017 | 20 | 2017 |
