| Genome-wide detection and characterization of positive selection in human populations PC Sabeti, P Varilly, B Fry, J Lohmueller, E Hostetter, C Cotsapas, X Xie, ... Nature 449 (7164), 913-918, 2007 | 2338 | 2007 |
| Positive natural selection in the human lineage PC Sabeti, SF Schaffner, B Fry, J Lohmueller, P Varilly, O Shamovsky, ... science 312 (5780), 1614-1620, 2006 | 1399 | 2006 |
| Synthetic biology in mammalian cells: next generation research tools and therapeutics F Lienert, JJ Lohmueller, A Garg, PA Silver Nature reviews Molecular cell biology 15 (2), 95-107, 2014 | 363 | 2014 |
| Modeling recent human evolution in mice by expression of a selected EDAR variant YG Kamberov, S Wang, J Tan, P Gerbault, A Wark, L Tan, Y Yang, S Li, ... Cell 152 (4), 691-702, 2013 | 313 | 2013 |
| Engineering synthetic TAL effectors with orthogonal target sites A Garg, JJ Lohmueller, PA Silver, TZ Armel Nucleic acids research 40 (15), 7584-7595, 2012 | 219 | 2012 |
| A tunable zinc finger-based framework for Boolean logic computation in mammalian cells JJ Lohmueller, TZ Armel, PA Silver Nucleic acids research 40 (11), 5180-5187, 2012 | 164 | 2012 |
| mSA2 affinity-enhanced biotin-binding CAR T cells for universal tumor targeting JJ Lohmueller, JD Ham, M Kvorjak, OJ Finn Oncoimmunology 7 (1), e1368604, 2018 | 139 | 2018 |
| Rationally designed logic integration of regulatory signals in mammalian cells M Leisner, L Bleris, J Lohmueller, Z Xie, Y Benenson Nature nanotechnology 5 (9), 666-670, 2010 | 124 | 2010 |
| Current modalities in cancer immunotherapy: Immunomodulatory antibodies, CARs and vaccines J Lohmueller, OJ Finn Pharmacology & therapeutics 178, 31-47, 2017 | 119 | 2017 |
| Protein scaffold-activated protein trans-splicing in mammalian cells DF Selgrade, JJ Lohmueller, F Lienert, PA Silver Journal of the American Chemical Society 135 (20), 7713-7719, 2013 | 59 | 2013 |
| Post-translational covalent assembly of CAR and synNotch receptors for programmable antigen targeting E Ruffo, AA Butchy, Y Tivon, V So, M Kvorjak, A Parikh, EL Adams, ... Nature Communications 14 (1), 2463, 2023 | 47 | 2023 |
| The costimulatory activity of Tim-3 requires Akt and MAPK signaling and its recruitment to the immune synapse S Kataoka, P Manandhar, J Lee, CJ Workman, H Banerjee, ... Science signaling 14 (687), eaba0717, 2021 | 41 | 2021 |
| Metabolic reprogramming via an engineered PGC-1α improves human chimeric antigen receptor T-cell therapy against solid tumors K Lontos, Y Wang, SK Joshi, AT Frisch, MLJ Watson, A Kumar, AV Menk, ... Journal for Immunotherapy of Cancer 11 (3), 2023 | 39 | 2023 |
| Antibodies elicited by the first non-viral prophylactic cancer vaccine show tumor-specificity and immunotherapeutic potential JJ Lohmueller, S Sato, L Popova, IM Chu, MA Tucker, R Barberena, ... Scientific reports 6 (1), 31740, 2016 | 39 | 2016 |
| Abnormally glycosylated MUC1 establishes a positive feedback circuit of inflammatory cytokines, mediated by NF-κB p65 and EzH2, in colitis-associated cancer S Cascio, JL Faylo, JC Sciurba, J Xue, S Ranganathan, JJ Lohmueller, ... Oncotarget 8 (62), 105284, 2017 | 16 | 2017 |
| MicroRNA circuits for transcriptional logic M Leisner, L Bleris, J Lohmueller, Z Xie, Y Benenson Synthetic Gene Networks: Methods and Protocols, 169-186, 2012 | 14 | 2012 |
| Conditional control of universal CAR T cells by cleavable OFF-switch adaptors M Kvorjak, E Ruffo, Y Tivon, V So, A Parikh, A Deiters, J Lohmueller ACS Synthetic Biology 12 (10), 2996-3007, 2023 | 12 | 2023 |
| Progress toward construction and modelling of a tri-stable toggle switch in E. coli J Lohmueller, N Neretti, B Hickey, A Kaka, A Gao, J Lemon, V Lattanzi, ... IET Synthetic Biology 1 (1), 25-28, 2007 | 10 | 2007 |
| 112 Tumor-specific reactivity and effector function of chimeric antigen receptor engineered macrophages targeting MUC1 S Eisenberg, A Powers, J Lohmueller, J Luketich, R Dhupar, A Soloff Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021 | 4 | 2021 |
| Fully murine CD105-targeted CAR-T cells provide an immunocompetent model for CAR-T cell biology K Lontos, Y Wang, M Colbert, A Kumar, S Joshi, M Philbin, Y Wang, ... Oncoimmunology 11 (1), 2131229, 2022 | 3 | 2022 |
Pamela SilverProfessor of Systems Biology, Harvard Medical Schoolhms.harvard.edu üzerinde doğrulanmış e-posta adresine sahip