| Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use M Liu, Y Jiang, R Wedow, Y Li, DM Brazel, F Chen, G Datta, ... Nature genetics 51 (2), 237-244, 2019 | 1740 | 2019 |
| Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant T Vang, M Congia, MD Macis, L Musumeci, V Orrú, P Zavattari, K Nika, ... Nature genetics 37 (12), 1317-1319, 2005 | 904 | 2005 |
| Complex genetic signatures in immune cells underlie autoimmunity and inform therapy V Orrù, M Steri, C Sidore, M Marongiu, V Serra, S Olla, G Sole, S Lai, ... Nature genetics 52 (10), 1036-1045, 2020 | 618 | 2020 |
| Overexpression of the cytokine BAFF and autoimmunity risk M Steri, V Orrù, ML Idda, M Pitzalis, M Pala, I Zara, C Sidore, V Faà, ... New England Journal of Medicine 376 (17), 1615-1626, 2017 | 409 | 2017 |
| Genetic variants regulating immune cell levels in health and disease V Orrù, M Steri, G Sole, C Sidore, F Virdis, M Dei, S Lai, M Zoledziewska, ... Cell 155 (1), 242-256, 2013 | 400 | 2013 |
| Genetic diversity fuels gene discovery for tobacco and alcohol use GRB Saunders, X Wang, F Chen, SK Jang, M Liu, C Wang, S Gao, ... Nature 612 (7941), 720-724, 2022 | 274 | 2022 |
| The longitudinal dynamics and natural history of clonal haematopoiesis MA Fabre, JG de Almeida, E Fiorillo, E Mitchell, A Damaskou, J Rak, ... Nature 606 (7913), 335-342, 2022 | 267 | 2022 |
| Genetic variants in mRNA untranslated regions M Steri, ML Idda, MB Whalen, V Orrù Wiley Interdisciplinary Reviews: RNA 9 (4), e1474, 2018 | 161 | 2018 |
| A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus V Orru, SJ Tsai, B Rueda, E Fiorillo, SM Stanford, J Dasgupta, J Hartiala, ... Human molecular genetics 18 (3), 569-579, 2009 | 155 | 2009 |
| Gold (I)-mediated inhibition of protein tyrosine phosphatases: a detailed in vitro and cellular study D Krishnamurthy, MR Karver, E Fiorillo, V Orru, SM Stanford, N Bottini, ... Journal of medicinal chemistry 51 (15), 4790-4795, 2008 | 150 | 2008 |
| Autoimmune-associated PTPN22 R620W variation reduces phosphorylation of lymphoid phosphatase on an inhibitory tyrosine residue E Fiorillo, V Orru, SM Stanford, Y Liu, M Salek, N Rapini, AD Schenone, ... Journal of biological chemistry 285 (34), 26506-26518, 2010 | 124 | 2010 |
| Number of autoantibodies and HLA genotype, more than high titers of glutamic acid decarboxylase autoantibodies, predict insulin dependence in latent autoimmune diabetes of adults M Maioli, GM Pes, G Delitala, L Puddu, A Falorni, F Tolu, R Lampis, ... European journal of endocrinology 163 (4), 541-549, 2010 | 106 | 2010 |
| Further Evidence of a Primary, Causal Association of the PTPN22 620W Variant With Type 1 Diabetes M Zoledziewska, C Perra, V Orru, L Moi, P Frongia, M Congia, N Bottini, ... Diabetes 57 (1), 229-234, 2008 | 62 | 2008 |
| Crystal structure of the human lymphoid tyrosine phosphatase catalytic domain: insights into redox regulation SJ Tsai, U Sen, L Zhao, WB Greenleaf, J Dasgupta, E Fiorillo, V Orrú, ... Biochemistry 48 (22), 4838-4845, 2009 | 61 | 2009 |
| Depressive symptoms, thyroid hormone and autoimmunity in a population-based cohort from Sardinia AP Delitala, A Terracciano, E Fiorillo, V Orrù, D Schlessinger, F Cucca Journal of affective disorders 191, 82-87, 2016 | 56 | 2016 |
| Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection SK Ahuja, MS Manoharan, GC Lee, LR McKinnon, JA Meunier, M Steri, ... Nature communications 14 (1), 3286, 2023 | 55 | 2023 |
| Effect of different disease-modifying therapies on humoral response to BNT162b2 vaccine in Sardinian multiple sclerosis patients M Pitzalis, ML Idda, V Lodde, A Loizedda, M Lobina, M Zoledziewska, ... Frontiers in immunology 12, 781843, 2021 | 47 | 2021 |
| CXCR3 identifies human naive CD8+ T cells with enhanced effector differentiation potential G De Simone, E Mazza, A Cassotta, AN Davydov, M Kuka, V Zanon, ... The Journal of Immunology 203 (12), 3179-3189, 2019 | 47 | 2019 |
| Immunologic resilience and COVID-19 survival advantage GC Lee, MI Restrepo, N Harper, MS Manoharan, AM Smith, JA Meunier, ... Journal of Allergy and Clinical Immunology 148 (5), 1176-1191, 2021 | 38 | 2021 |
| Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells … RC Ferreira, X Castro Dopico, JJ Oliveira, DB Rainbow, JH Yang, ... Frontiers in Immunology 10, 2606, 2019 | 36 | 2019 |
