Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication W Vuong, MB Khan, C Fischer, E Arutyunova, T Lamer, J Shields, ... Nature communications 11 (1), 4282, 2020 | 476 | 2020 |
Peptidomimetic α-acyloxymethylketone warheads with six-membered lactam P1 glutamine mimic: SARS-CoV-2 3CL protease inhibition, coronavirus antiviral activity, and in vitro … B Bai, A Belovodskiy, M Hena, AS Kandadai, MA Joyce, HA Saffran, ... Journal of Medicinal Chemistry 65 (4), 2905-2925, 2021 | 100 | 2021 |
Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies W Vuong, C Fischer, MB Khan, MJ van Belkum, T Lamer, KD Willoughby, ... European Journal of Medicinal Chemistry 222, 113584, 2021 | 91 | 2021 |
Peptidomimetic nitrile warheads as SARS-CoV-2 3CL protease inhibitors B Bai, E Arutyunova, MB Khan, J Lu, MA Joyce, HA Saffran, JA Shields, ... RSC Medicinal Chemistry 12 (10), 1722-1730, 2021 | 51 | 2021 |
SARS-CoV-2 Mpro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals SA Chen, E Arutyunova, J Lu, MB Khan, W Rut, M Zmudzinski, S Shahbaz, ... ACS Central Science 9 (4), 696-708, 2023 | 43 | 2023 |
N-Terminal finger stabilizes the S1 pocket for the reversible feline drug GC376 in the SARS-CoV-2 Mpro dimer E Arutyunova, MB Khan, C Fischer, J Lu, T Lamer, W Vuong, ... Journal of Molecular Biology 433 (13), 167003, 2021 | 38 | 2021 |
Crystallization of feline coronavirus Mpro with GC376 reveals mechanism of inhibition J Lu, SA Chen, MB Khan, R Brassard, E Arutyunova, T Lamer, W Vuong, ... Frontiers in Chemistry 10, 852210, 2022 | 32 | 2022 |
Structural and functional characterization of the N-terminal domain of the yeast Mg2+ channel Mrs2 MB Khan, G Sponder, B Sjöblom, S Svidová, RJ Schweyen, O Carugo, ... Acta Crystallographica Section D: Biological Crystallography 69 (9), 1653-1664, 2013 | 25 | 2013 |
Calcium modulates the domain flexibility and function of an α-actinin similar to the ancestral α-actinin N Pinotsis, K Zielinska, M Babuta, JL Arolas, J Kostan, MB Khan, ... Proceedings of the National Academy of Sciences 117 (36), 22101-22112, 2020 | 18 | 2020 |
New insight in staphylococcin research: bacteriocin and/or bacteriocin-like inhibitory substance(s) produced by S. aureus AB188 S Saeed, SA Rasool, S Ahmed, T Khanum, MB Khan, A Abbasi, SA Ali World Journal of Microbiology and Biotechnology 22, 713-722, 2006 | 18 | 2006 |
The GMN motif determines ion selectivity in the yeast magnesium channel Mrs2p G Sponder, S Svidová, MB Khan, M Kolisek, RJ Schweyen, O Carugo, ... Metallomics 5 (6), 745-752, 2013 | 17 | 2013 |
Fluorescence enhancement strategy for evaluation of the minor groove binder DAPI to complementary ssDNA sequence including telomere mimics in (ssDNA@ DAPI/LDH) n ultrathin films MS Haroone, Y Hu, P Zhang, R Ma, X Zhang, QM Kaleem, MB Khan, J Lu Dyes and Pigments 166, 422-432, 2019 | 15 | 2019 |
Overview of Helicobacter pylori Infection, Prevalence, Risk Factors, and Its Prevention SK Bashir, MB Khan Advanced Gut & Microbiome Research 2023 (1), 9747027, 2023 | 13 | 2023 |
Purification and biochemical properties of SDS-stable low molecular weight alkaline serine protease from Citrullus colocynthis MB Khan, H Khan, MU Shah, S Khan Natural product research 30 (8), 935-940, 2016 | 12 | 2016 |
Production and physico-chemical characterization of bacteriocins-like inhibitory substances from marine bacterium ZM81 ZA Pirzada, SA Ali, BM Khan, SA Rasool | 11 | 2004 |
Crystallization and preliminary X-ray diffraction analysis of the N-terminal domain of Mrs2, a magnesium ion transporter from yeast inner mitochondrial membrane MB Khan, B Sjöblom, RJ Schweyen, K Djinović-Carugo Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010 | 7 | 2010 |
Primitive Phospholamban-and Sarcolipin-like Peptides Inhibit the Sarcoplasmic Reticulum Calcium Pump SERCA JJ Bak, R Aguayo-Ortiz, N Rathod, JO Primeau, MB Khan, SL Robia, ... Biochemistry 61 (14), 1419-1430, 2022 | 5 | 2022 |
The Effect of Deuteration and Homologation of the Lactam Ring of Nirmatrelvir on Its Biochemical Properties and Oxidative Metabolism E Arutyunova, A Belovodskiy, P Chen, MB Khan, M Joyce, H Saffran, J Lu, ... ACS Bio & Med Chem Au 3 (6), 528-541, 2023 | 4 | 2023 |
Pediatric Functional Constipation: A New Challenge SK Bashir, MB Khan Advanced Gut & Microbiome Research 2024 (1), 5569563, 2024 | 2 | 2024 |
N-Terminal finger stabilizes the reversible feline drug GC376 in SARS-CoV-2 Mpro E Arutyunova, MB Khan, C Fischer, J Lu, T Lamer, W Vuong, ... BioRxiv, 2021.02. 16.431021, 2021 | 2 | 2021 |