The neurobiology of antiepileptic drugs MA Rogawski, W Löscher Nature reviews neuroscience 5 (7), 553-564, 2004 | 1535 | 2004 |
Blood-brain barrier active efflux transporters: ATP-binding cassette gene family W Löscher, H Potschka NeuroRx 2 (1), 86-98, 2005 | 1096 | 2005 |
Drug resistance in brain diseases and the role of drug efflux transporters W Löscher, H Potschka Nature Reviews Neuroscience 6 (8), 591-602, 2005 | 1077 | 2005 |
Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations W Löscher, D Schmidt Epilepsy research 2 (3), 145-181, 1988 | 1053 | 1988 |
Critical review of current animal models of seizures and epilepsy used in the discovery and development of new antiepileptic drugs W Löscher Seizure 20 (5), 359-368, 2011 | 1048 | 2011 |
The blood-brain barrier and cancer: transporters, treatment, and Trojan horses JF Deeken, W Löscher Clinical cancer research 13 (6), 1663-1674, 2007 | 876 | 2007 |
Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy W Löscher CNS drugs 16, 669-694, 2002 | 847 | 2002 |
Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases W Löscher, H Potschka Progress in neurobiology 76 (1), 22-76, 2005 | 776 | 2005 |
New avenues for anti-epileptic drug discovery and development W Löscher, H Klitgaard, RE Twyman, D Schmidt Nature reviews drug discovery 12 (10), 757-776, 2013 | 717 | 2013 |
Drug resistance in epilepsy: clinical impact, potential mechanisms, and new innovative treatment options W Löscher, H Potschka, SM Sisodiya, A Vezzani, EL Barker Pharmacological reviews 72 (3), 606-638, 2020 | 707 | 2020 |
Animal models of epilepsy for the development of antiepileptogenic and disease-modifying drugs. A comparison of the pharmacology of kindling and post-status epilepticus models … W Löscher Epilepsy research 50 (1-2), 105-123, 2002 | 701 | 2002 |
Modern antiepileptic drug development has failed to deliver: ways out of the current dilemma W Löscher, D Schmidt Epilepsia 52 (4), 657-678, 2011 | 685 | 2011 |
Valproate: a reappraisal of its pharmacodynamic properties and mechanisms of action W Löscher Progress in neurobiology 58 (1), 31-59, 1999 | 685 | 1999 |
Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind … JF Howard, K Utsugisawa, M Benatar, H Murai, RJ Barohn, I Illa, S Jacob, ... The Lancet Neurology 16 (12), 976-986, 2017 | 684 | 2017 |
Drug resistance in epilepsy: putative neurobiologic and clinical mechanisms D Schmidt, W Löscher Epilepsia 46 (6), 858-877, 2005 | 682 | 2005 |
Infections, inflammation and epilepsy A Vezzani, RS Fujinami, HS White, PM Preux, I Blümcke, JW Sander, ... Acta neuropathologica 131, 211-234, 2016 | 611 | 2016 |
Role of multidrug transporters in pharmacoresistance to antiepileptic drugs W Löscher, H Potschka Journal of pharmacology and experimental therapeutics 301 (1), 7-14, 2002 | 600 | 2002 |
The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions MA Rogawski, W Löscher Nature medicine 10 (7), 685-692, 2004 | 591 | 2004 |
Prevention or modification of epileptogenesis after brain insults: experimental approaches and translational research W Löscher, C Brandt, D Sibley Pharmacological reviews 62 (4), 668-700, 2010 | 475 | 2010 |
Antiepileptogenic effects of the novel anticonvulsant levetiracetam (ucb L059) in the kindling model of temporal lobe epilepsy W Löscher, D Hönack, C Rundfeldt Journal of Pharmacology and Experimental Therapeutics 284 (2), 474-479, 1998 | 448 | 1998 |