SCENIC: single-cell regulatory network inference and clustering S Aibar, CB González-Blas, T Moerman, VA Huynh-Thu, H Imrichova, ... Nature methods 14 (11), 1083-1086, 2017 | 4302 | 2017 |
Melanoma addiction to the long non-coding RNA SAMMSON E Leucci, R Vendramin, M Spinazzi, P Laurette, M Fiers, J Wouters, ... Nature 531 (7595), 518-522, 2016 | 577 | 2016 |
Tumor vessel normalization by chloroquine independent of autophagy H Maes, A Kuchnio, A Peric, S Moens, K Nys, K De Bock, A Quaegebeur, ... Cancer cell 26 (2), 190-206, 2014 | 443 | 2014 |
cisTopic: cis-regulatory topic modeling on single-cell ATAC-seq data C Bravo González-Blas, L Minnoye, D Papasokrati, S Aibar, ... Nature methods 16 (5), 397-400, 2019 | 368 | 2019 |
SCENIC+: single-cell multiomic inference of enhancers and gene regulatory networks C Bravo González-Blas, S De Winter, G Hulselmans, N Hecker, ... Nature methods 20 (9), 1355-1367, 2023 | 291 | 2023 |
Keratin 19: a key role player in the invasion of human hepatocellular carcinomas O Govaere, M Komuta, J Berkers, B Spee, C Janssen, F de Luca, ... Gut 63 (4), 674-685, 2014 | 289 | 2014 |
Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma J Wouters, Z Kalender-Atak, L Minnoye, KI Spanier, M De Waegeneer, ... Nature Cell Biology 22 (8), 986-998, 2020 | 203 | 2020 |
Expression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching L De Smedt, S Palmans, D Andel, O Govaere, B Boeckx, D Smeets, ... British journal of cancer 116 (1), 58-65, 2017 | 173 | 2017 |
A cellular hierarchy in melanoma uncouples growth and metastasis P Karras, I Bordeu, J Pozniak, A Nowosad, C Pazzi, N Van Raemdonck, ... Nature 610 (7930), 190-198, 2022 | 156 | 2022 |
The transcription factor Grainy head primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes J Jacobs, M Atkins, K Davie, H Imrichova, L Romanelli, V Christiaens, ... Nature genetics 50 (7), 1011-1020, 2018 | 152 | 2018 |
Laminin-332 sustains chemoresistance and quiescence as part of the human hepatic cancer stem cell niche O Govaere, J Wouters, M Petz, YP Vandewynckel, K Van den Eynde, ... Journal of hepatology 64 (3), 609-617, 2016 | 141 | 2016 |
Antitumor immunity triggered by melphalan is potentiated by melanoma cell surface–associated calreticulin AM Dudek-Perić, GB Ferreira, A Muchowicz, J Wouters, N Prada, S Martin, ... Cancer research 75 (8), 1603-1614, 2015 | 113 | 2015 |
Macrophage scavenger receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease O Govaere, SK Petersen, N Martinez-Lopez, J Wouters, M Van Haele, ... Journal of hepatology 76 (5), 1001-1012, 2022 | 110 | 2022 |
Cross-species analysis of enhancer logic using deep learning L Minnoye, II Taskiran, D Mauduit, M Fazio, L Van Aerschot, ... Genome research 30 (12), 1815-1834, 2020 | 95 | 2020 |
Human pancreatic cancer contains a side population expressing cancer stem cell-associated and prognostic genes A Van den broeck, H Vankelecom, W Van Delm, L Gremeaux, J Wouters, ... PloS one 8 (9), e73968, 2013 | 84 | 2013 |
Comprehensive DNA methylation study identifies novel progression-related and prognostic markers for cutaneous melanoma J Wouters, M Vizoso, A Martinez-Cardus, FJ Carmona, O Govaere, ... BMC medicine 15, 1-16, 2017 | 82 | 2017 |
The EMT transcription factor ZEB2 promotes proliferation of primary and metastatic melanoma while suppressing an invasive, mesenchymal-like phenotype N Vandamme, G Denecker, K Bruneel, G Blancke, Ö Akay, J Taminau, ... Cancer research 80 (14), 2983-2995, 2020 | 78 | 2020 |
The PDGFRα-laminin B1-keratin 19 cascade drives tumor progression at the invasive front of human hepatocellular carcinoma O Govaere, M Petz, J Wouters, YP Vandewynckel, EJ Scott, B Topal, ... Oncogene 36 (47), 6605-6616, 2017 | 72 | 2017 |
BNIP3 promotes HIF‐1α‐driven melanoma growth by curbing intracellular iron homeostasis M Vara‐Pérez, M Rossi, C Van den Haute, H Maes, ML Sassano, ... The EMBO journal 40 (10), e106214, 2021 | 63 | 2021 |
Yin Yang 1 orchestrates a metabolic program required for both neural crest development and melanoma formation S Varum, A Baggiolini, L Zurkirchen, ZK Atak, C Cantu, E Marzorati, ... Cell stem cell 24 (4), 637-653. e9, 2019 | 59 | 2019 |