Animal models for COVID-19 C Muñoz-Fontela, WE Dowling, SGP Funnell, PS Gsell, AX Riveros-Balta, ... Nature 586 (7830), 509-515, 2020 | 882 | 2020 |
Favipiravir as a potential countermeasure against neglected and emerging RNA viruses L Delang, R Abdelnabi, J Neyts Antiviral research 153, 85-94, 2018 | 497 | 2018 |
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2− infected hamsters, whereas hydroxychloroquine lacks activity SJF Kaptein, S Jacobs, L Langendries, L Seldeslachts, S Ter Horst, ... Proceedings of the National Academy of Sciences 117 (43), 26955-26965, 2020 | 320 | 2020 |
STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters R Boudewijns, HJ Thibaut, SJF Kaptein, R Li, V Vergote, L Seldeslachts, ... Nature communications 11 (1), 5838, 2020 | 294 | 2020 |
Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral L Delang, N Segura Guerrero, A Tas, G Quérat, B Pastorino, M Froeyen, ... Journal of Antimicrobial Chemotherapy 69 (10), 2770-2784, 2014 | 273 | 2014 |
Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein JRPM Strating, L van der Linden, L Albulescu, J Bigay, M Arita, L Delang, ... Cell reports 10 (4), 600-615, 2015 | 263 | 2015 |
Towards antivirals against chikungunya virus R Abdelnabi, J Neyts, L Delang Antiviral research 121, 59-68, 2015 | 151 | 2015 |
Statins potentiate the in vitro anti‐hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development L Delang, J Paeshuyse, I Vliegen, P Leyssen, S Obeid, D Durantel, ... Hepatology 50 (1), 6-16, 2009 | 137 | 2009 |
Stable distinct core eukaryotic viromes in different mosquito species from Guadeloupe, using single mosquito viral metagenomics C Shi, L Beller, W Deboutte, KC Yinda, L Delang, A Vega-Rúa, ... Microbiome 7, 1-20, 2019 | 135 | 2019 |
Prostratin and 12-O-Tetradecanoylphorbol 13-Acetate Are Potent and Selective Inhibitors of Chikungunya Virus Replication M Bourjot, L Delang, VH Nguyen, J Neyts, F Guéritte, P Leyssen, ... Journal of natural products 75 (12), 2183-2187, 2012 | 132 | 2012 |
Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus M Bassetto, T De Burghgraeve, L Delang, A Massarotti, A Coluccia, ... Antiviral research 98 (1), 12-18, 2013 | 126 | 2013 |
Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains F Aubry, S Jacobs, M Darmuzey, S Lequime, L Delang, A Fontaine, ... Nature Communications 12 (1), 916, 2021 | 123 | 2021 |
Comparing infectivity and virulence of emerging SARS-CoV-2 variants in Syrian hamsters R Abdelnabi, R Boudewijns, CS Foo, L Seldeslachts, L Sanchez-Felipe, ... EBioMedicine 68, 2021 | 117* | 2021 |
The viral capping enzyme nsP1: a novel target for the inhibition of chikungunya virus infection L Delang, C Li, A Tas, G Quérat, IC Albulescu, T De Burghgraeve, ... Scientific reports 6 (1), 31819, 2016 | 111 | 2016 |
The postbinding activity of scavenger receptor class B type I mediates initiation of hepatitis C virus infection and viral dissemination MN Zahid, M Turek, F Xiao, VL Dao Thi, M Guérin, I Fofana, P Bachellier, ... Hepatology 57 (2), 492-504, 2013 | 103 | 2013 |
The role of phosphatidylinositol 4-kinases and phosphatidylinositol 4-phosphate during viral replication L Delang, J Paeshuyse, J Neyts Biochemical pharmacology 84 (11), 1400-1408, 2012 | 96 | 2012 |
The future of antivirals: broad-spectrum inhibitors Y Debing, J Neyts, L Delang Current opinion in infectious diseases 28 (6), 596-602, 2015 | 90 | 2015 |
Antiviral activity of diterpene esters on chikungunya virus and HIV replication LF Nothias-Scaglia, C Pannecouque, F Renucci, L Delang, J Neyts, ... Journal of natural products 78 (6), 1277-1283, 2015 | 87 | 2015 |
Identification of [1,2,3]Triazolo[4,5-d]pyrimidin-7(6H)-ones as Novel Inhibitors of Chikungunya Virus Replication A Gigante, MD Canela, L Delang, EM Priego, MJ Camarasa, G Querat, ... Journal of Medicinal Chemistry 57 (10), 4000-4008, 2014 | 87 | 2014 |
Understanding the mechanism of the broad-spectrum antiviral activity of favipiravir (T-705): key role of the F1 motif of the viral polymerase R Abdelnabi, ATS Morais, P Leyssen, I Imbert, S Beaucourt, H Blanc, ... Journal of virology 91 (12), 10.1128/jvi. 00487-17, 2017 | 78 | 2017 |