TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A AL Brown, OG Wilkins, MJ Keuss, SE Hill, M Zanovello, WC Lee, ... Nature 603 (7899), 131-137, 2022 | 303 | 2022 |
Alpha-2 macroglobulin in Alzheimer’s disease: a marker of neuronal injury through the RCAN1 pathway VR Varma, S Varma, Y An, TJ Hohman, S Seddighi, R Casanova, A Beri, ... Molecular psychiatry 22 (1), 13-23, 2017 | 140 | 2017 |
Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD S Seddighi, YA Qi, AL Brown, OG Wilkins, C Bereda, C Belair, YJ Zhang, ... Science Translational Medicine 16 (734), eadg7162, 2024 | 80 | 2024 |
Social play in juvenile hamsters alters dendritic morphology in the medial prefrontal cortex and attenuates effects of social stress in adulthood. CA Burleson, RW Pedersen, S Seddighi, LE DeBusk, GM Burghardt, ... Behavioral Neuroscience 130 (4), 437, 2016 | 77 | 2016 |
At the crossroads between neurodegeneration and cancer: a review of overlapping biology and its implications AL Houck, S Seddighi, JA Driver Current aging science 11 (2), 77-89, 2018 | 74 | 2018 |
Sparcl1 Accelerates Symptom Onset in Alzheimer’s Disease and Influences Brain Structure and Function During Aging S Seddighi, VR Varma, Y An, S Varma, LL Beason-Held, T Tanaka, ... Alzheimer's & Dementia 13 (7), P974-P975, 2017 | 36 | 2017 |
Evidence of a Causal Association Between Cancer and Alzheimer's Disease: a Mendelian Randomization Analysis S Seddighi, AL Houck, JB Rowe, PDP Pharoah Sci Reports, 2019 | 35 | 2019 |
α2-macroglobulin in Alzheimer’s disease: new roles for an old chaperone S Seddighi, V Varma, M Thambisetty Biomarkers in Medicine 12 (4), 311-314, 2018 | 13 | 2018 |
Disentangling the genetic overlap and causal relationships between primary open-angle glaucoma, brain morphology and four major neurodegenerative disorders S Diaz-Torres, W He, J Thorp, S Seddighi, S Mullany, CJ Hammond, ... Lancet EBioMed 92, 2023 | 12 | 2023 |
Dominance status alters restraint-induced neural activity in brain regions controlling stress vulnerability MA Cooper, S Seddighi, AK Barnes, JA Grizzell, BN Dulka, CT Clinard Physiology & behavior 179, 153-161, 2017 | 12 | 2017 |
Variant biomarker discovery using mass spectrometry-based proteogenomics L Reilly*, S Seddighi*, AB Singleton, MR Cookson, ME Ward, YA Qi Frontiers in Aging 4, 2023 | 6 | 2023 |
Frontotemporal lobar degeneration targets brain regions linked to expression of recently evolved genes L Pasquini, FL Pereira, S Seddighi, Y Zeng, Y Wei, I Illán-Gala, ... Brain, 2024 | 1 | 2024 |
Author Correction: TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A AL Brown, OG Wilkins, MJ Keuss, SE Hill, M Zanovello, WC Lee, ... Nature 631 (8020), E7-E7, 2024 | | 2024 |
Maintenance of neuronal TDP-43 expression requires axonal lysosome transport VH Ryan, S Lawton, JF Reyes, J Hawrot, AM Frankenfield, S Seddighi, ... eLife, 14:RP104057, 2024 | | 2024 |
Proteogenomic Identification of TDP-43-Related Splicing Biomarkers in Frontotemporal Dementia S Seddighi, A Qi, AL Brown, C Bereda, Y Zhang, M Prudencio, S Hill, ... Alzheimer's Association International Conference, 2023 | | 2023 |
Developing biomarkers of TDP‐43‐related splicing dysfunction in frontotemporal dementia S Seddighi, S Hill, AL Brown, A Qi, J Hawrot, S Coon, L Petrucelli, P Fratta, ... Alzheimer's & Dementia 17, e055170, 2021 | | 2021 |
Evidence of a Causal Association Between Cancer and Alzheimer’s Disease: A Mendelian Randomization Analysis (2597) S Seddighi, A Houck, J Rowe, P Pharoah Neurology 94 (15_supplement), 2597, 2020 | | 2020 |
[P3–103]: SPARCL1 ACCELERATES SYMPTOM ONSET IN ALZHEIMER's DISEASE AND INFLUENCES BRAIN STRUCTURE AND FUNCTION DURING AGING S Seddighi, VR Varma, Y An, S Varma, LL Beason‐Held, T Tanaka, ... Alzheimer's & Dementia 13 (7S_Part_20), P974-P975, 2017 | | 2017 |
Social Status Modulates Restraint-Induced Neural Activity in Brain Regions Controlling Stress Vulnerability S Seddighi, MA Cooper TRACE: Tennessee Research and Creative Exchange, 2017 | | 2017 |