Maternal diet and aging alter the epigenetic control of a promoter–enhancer interaction at the Hnf4a gene in rat pancreatic islets I Sandovici, NH Smith, MD Nitert, M Ackers-Johnson, S Uribe-Lewis, Y Ito, ... Proceedings of the National Academy of Sciences 108 (13), 5449-5454, 2011 | 401 | 2011 |
Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems M Constância, E Angiolini, I Sandovici, P Smith, R Smith, G Kelsey, ... Proceedings of the National Academy of Sciences 102 (52), 19219-19224, 2005 | 371 | 2005 |
Regulation of placental efficiency for nutrient transport by imprinted genes E Angiolini, A Fowden, P Coan, I Sandovici, P Smith, W Dean, G Burton, ... Placenta 27, 98-102, 2006 | 260 | 2006 |
Placental adaptations to the maternal–fetal environment: implications for fetal growth and developmental programming I Sandovici, K Hoelle, E Angiolini, M Constância Reproductive biomedicine online 25 (1), 68-89, 2012 | 253 | 2012 |
Adaptations in placental nutrient transfer capacity to meet fetal growth demands depend on placental size in mice PM Coan, E Angiolini, I Sandovici, GJ Burton, M Constancia, AL Fowden The Journal of physiology 586 (18), 4567-4576, 2008 | 214 | 2008 |
Placental phenotype and the insulin‐like growth factors: resource allocation to fetal growth AN Sferruzzi‐Perri, I Sandovici, M Constancia, AL Fowden The Journal of physiology 595 (15), 5057-5093, 2017 | 182 | 2017 |
Familial aggregation of abnormal methylation of parental alleles at the IGF2/H19 and IGF2R differentially methylated regions I Sandovici, M Leppert, PR Hawk, A Suarez, Y Linares, C Sapienza Human Molecular Genetics 12 (13), 1569-1578, 2003 | 118 | 2003 |
Interindividual variability and parent of origin DNA methylation differences at specific human Alu elements I Sandovici, S Kassovska-Bratinova, JC Loredo-Osti, M Leppert, A Suarez, ... Human Molecular Genetics 14 (15), 2135-2143, 2005 | 102 | 2005 |
Differential genomic imprinting regulates paracrine and autocrine roles of IGF2 in mouse adult neurogenesis SR Ferrón, EJ Radford, A Domingo-Muelas, I Kleine, A Ramme, D Gray, ... Nature communications 6 (1), 8265, 2015 | 99 | 2015 |
A longitudinal study of X-inactivation ratio in human females I Sandovici, AK Naumova, M Leppert, Y Linares, C Sapienza Human genetics 115, 387-392, 2004 | 79 | 2004 |
The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth I Sandovici, A Georgopoulou, V Pérez-García, A Hufnagel, J López-Tello, ... Developmental Cell 57 (1), 63-79. e8, 2022 | 78 | 2022 |
Insulin-like growth factor II: an essential adult stem cell niche constituent in brain and intestine AN Ziegler, Q Feng, S Chidambaram, JM Testai, E Kumari, DE Rothbard, ... Stem cell reports 12 (4), 816-830, 2019 | 69 | 2019 |
Developmental adaptations to increased fetal nutrient demand in mouse genetic models of Igf2‐mediated overgrowth E Angiolini, PM Coan, I Sandovici, OH Iwajomo, G Peck, GJ Burton, ... The FASEB Journal 25 (5), 1737-1745, 2011 | 68 | 2011 |
Extracardiac control of embryonic cardiomyocyte proliferation and ventricular wall expansion H Shen, S Cavallero, KD Estrada, I Sandovici, SR Kumar, T Makita, ... Cardiovascular research 105 (3), 271-278, 2015 | 67 | 2015 |
Sex-specific regulation of stress-induced fetal glucocorticoid surge by the mouse placenta A Wieczorek, CV Perani, M Nixon, M Constancia, I Sandovici, DE Zazara, ... American Journal of Physiology-Endocrinology and Metabolism 317 (1), E109-E120, 2019 | 56 | 2019 |
Developmental and environmental epigenetic programming of the endocrine pancreas: consequences for type 2 diabetes I Sandovici, CM Hammerle, SE Ozanne, M Constância Cellular and Molecular Life Sciences 70, 1575-1595, 2013 | 56 | 2013 |
Human imprinted chromosomal regions are historical hot-spots of recombination I Sandovici, S Kassovska-Bratinova, JE Vaughan, R Stewart, M Leppert, ... PLoS Genetics 2 (7), e101, 2006 | 54 | 2006 |
Sex differences in the intergenerational inheritance of metabolic traits I Sandovici, DS Fernandez-Twinn, A Hufnagel, M Constância, SE Ozanne Nature Metabolism 4 (5), 507-523, 2022 | 50 | 2022 |
Adipose tissue dysfunction as a central mechanism leading to dysmetabolic obesity triggered by chronic exposure to p,p’-DDE D Pestana, D Teixeira, M Meireles, C Marques, S Norberto, C Sá, ... Scientific Reports 7 (1), 2738, 2017 | 50 | 2017 |
Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes VL Haley, DJ Barnes, I Sandovici, M Constancia, CF Graham, F Pezzella, ... EMBO molecular medicine 4 (8), 705-718, 2012 | 43 | 2012 |