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Julia A. Schulz Pauly
Julia A. Schulz Pauly
Diğer adlarJulia Annette Schulz, Julia A. Schulz
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Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
Characterization and comparison of human glioblastoma models
JA Schulz, LT Rodgers, RJ Kryscio, AMS Hartz, B Bauer
BMC cancer 22 (1), 844, 2022
352022
Isolation of cerebral capillaries from fresh human brain tissue
AMS Hartz, JA Schulz, BS Sokola, SE Edelmann, AN Shen, RG Rempe, ...
Journal of visualized experiments: JoVE, 57346, 2018
322018
ABCB1 and ABCG2 regulation at the blood-brain barrier: potential new targets to improve brain drug delivery
JA Schulz, AMS Hartz, B Bauer
Pharmacological Reviews 75 (5), 815-853, 2023
312023
Plasma protein-mediated uptake and contradictions to the free drug hypothesis: a critical review
JA Schulz, DM Stresser, JC Kalvass
Drug Metabolism Reviews 55 (3), 205-238, 2023
242023
Drug delivery to primary and metastatic brain tumors: challenges and opportunities
S Talele, AS Mohammad, JA Schulz, B Bauer, AMS Hartz, JN Sarkaria, ...
Drug delivery to the brain: physiological concepts, methodologies and …, 2022
32022
Hepatocyte uptake and loss assay (HUpLA): proof-of-concept of an all-in-one system for measuring hepatic influx, egress, and metabolic clearance based on the extended clearance …
JAS Pauly, E Sande, M Feng, YT Wang, DM Stresser, JC Kalvass
Drug Metab Dispos 52, 2024
22024
Assumptions underlying hepatic clearance models: recognizing the influence of saturable protein binding on driving force concentration and discrimination between models of …
JAS Pauly, J Wang, CJ Phipps, JC Kalvass
Drug Metabolism and Disposition 51 (8), 1046-1052, 2023
22023
CADD-16. DUAL PI3K/Akt INHIBITION TO OVERCOME THE P-gp/BCRP DRUG EFFLUX SYSTEM FOR IMPROVED DRUG DELIVERY IN GLIOBLASTOMA THERAPY
A Hartz, J Schulz, B Sokola, B Bauer
Neuro-oncology 20 (Suppl 6), vi279, 2018
12018
Clearance prediction with three novel plated human hepatocyte models compared to conventional suspension assays: Assessment with 50 compounds and multiple donors
DA Kukla, JAS Pauly, PR Lesniak, E Sande, YT Wang, JC Kalvass, ...
Drug Metabolism and Disposition 53 (2), 100032, 2025
2025
Proof of Concept of an All-in-One System for Measuring Hepatic Influx, Egress, and Metabolic Clearance Based on the Extended Clearance Concept
JAS Pauly, E Sande, M Feng, YT Wang, DM Stresser, JC Kalvass
Drug Metabolism and Disposition 52 (10), 1048-1059, 2024
2024
Improving in vitro clearance assay performance and prediction accuracy with advanced human hepatocyte models for highly stable RO5 and BRO5 compounds
D Kukla, J Pauly, C Kalvass, G Jenkins, D Stresser
Drug Metabolism and Pharmacokinetics 55, 100820, 2024
2024
442 Repurposing FDA-approved PI3K/Akt Inhibitors to Improve Anti-Cancer Drug Brain Uptake in Glioblastoma Resection Models
L Rodgers, Y Tega, JA Schulz, AMS Hartz, B Bauer
Journal of Clinical and Translational Science 6 (s1), 87-87, 2022
2022
ABC Transporters in Glioblastoma: Anticancer Drug Transport and Transporter Regulation at the Blood-brain Barrier
JA Schulz
2021
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