New series of 6-substituted coumarin derivatives as effective factor Xa inhibitors: Synthesis, in vivo antithrombotic evaluation and molecular docking KM Amin, NMA Gawad, DEA Rahman, MKM El Ashry Bioorganic chemistry 52, 31-43, 2014 | 53 | 2014 |
Rumex vesicarius L. boosts the effectiveness of sorafenib in triple-negative breast cancer by downregulating BCl2, mTOR, and JNK, and upregulating p21 expression A Ghanem, MA Ali, MA Elkady, SSA Mageed, MA El Hassab, ... Pathology-Research and Practice 250, 154807, 2023 | 22 | 2023 |
1-Benzyl-5-bromo-3-hydrazonoindolin-2-ones as novel anticancer agents: synthesis, biological evaluation and molecular modeling insights T Al-Warhi, H Almahli, RM Maklad, ZM Elsayed, MA El Hassab, ... Molecules 28 (7), 3203, 2023 | 22 | 2023 |
Synthesis and molecular docking of new roflumilast analogues as preferential-selective potent PDE-4B inhibitors with improved pharmacokinetic profile BA Moussa, AA El-Zaher, MK El-Ashrey, MA Fouad European Journal of Medicinal Chemistry 148, 477-486, 2018 | 18 | 2018 |
Identification of sulphonamide-tethered N-((triazol-4-yl)methyl)isatin derivatives as inhibitors of SARS-CoV-2 main protease MH ElNaggar, AA Elgazar, G Gamal, SM Hamed, ZM Elsayed, ... Journal of enzyme inhibition and medicinal chemistry 38 (1), 2234665, 2023 | 16 | 2023 |
Synergistic antiviral activity of Lactobacillus acidophilus and Glycyrrhiza glabra against Herpes Simplex-1 Virus (HSV-1) and Vesicular Stomatitis Virus (VSV): experimental … D Elebeedy, A Ghanem, SH Aly, MA Ali, AHI Faraag, MK El-Ashrey, ... BMC microbiology 23 (1), 173, 2023 | 15 | 2023 |
Novel pyridothienopyrimidine derivatives: Design, synthesis and biological evaluation as antimicrobial and anticancer agents EM Mohi El-Deen, MM Anwar, AAA El-Gwaad, EA Karam, MK El-Ashrey, ... Molecules 27 (3), 803, 2022 | 14 | 2022 |
Revolutionizing psoriasis topical treatment: enhanced efficacy through ceramide/phospholipid composite cerosomes co-delivery of cyclosporine and dithranol: in-vitro, ex-vivo … SF Elhabal, N Abdelaal, SAS Al-Zuhairy, MF Mohamed Elrefai, ... International Journal of Nanomedicine, 1163-1187, 2024 | 13 | 2024 |
Design and synthesis of some novel pyridothienopyrimidine derivatives and their biological evaluation as antimicrobial and anticancer agents targeting EGFR enzyme EMM El-Deen, MM Anwar, AA Abd El-Gwaad, EA Karam, MK El-Ashrey, ... Arabian Journal of Chemistry 15 (4), 103751, 2022 | 12 | 2022 |
Repurposing of renin inhibitors as SARS-COV-2 main protease inhibitors: A computational study RH Refaey, MK El-Ashrey, YM Nissan Virology 554, 48-54, 2021 | 11 | 2021 |
Synthesis, Biological, and Molecular Docking Studies on 4,5,6,7-Tetrahydrobenzo[b]thiophene Derivatives and Their Nanoparticles Targeting Colorectal Cancer S Kamal, HA Derbala, SS Alterary, A Ben Bacha, M Alonazi, MK El-Ashrey, ... ACS omega 6 (43), 28992-29008, 2021 | 10 | 2021 |
Pharmacophore based virtual screening for natural product database revealed possible inhibitors for SARS-COV-2 main protease MK El-Ashrey, RO Bakr, MAA Fayed, RH Refaey, YM Nissan Virology 570, 18-28, 2022 | 9 | 2022 |
Dual-target ligand discovery for Alzheimer’s disease: triphenylphosphoranylidene derivatives as inhibitors of acetylcholinesterase and β-amyloid aggregation M El-Hussieny, MA Abd-El-Maksoud, FM Soliman, MA Fouad, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2166040, 2023 | 8 | 2023 |
An innovative combination of Box-Behnken design and ecofriendly approaches for the simultaneous determination of aspirin, clopidogrel, atorvastatin and rosuvastatin in their … EA Mostafa, MK El‐Ashrey, ST Mahmoud BMC chemistry 17 (1), 164, 2023 | 8 | 2023 |
Evaluating the ability of some natural phenolic acids to target the main protease and AAK1 in SARS COV-2 HI Ghamry, A Belal, MK El-Ashrey, HO Tawfik, RI Alsantali, AJ Obaidullah, ... Scientific Reports 13 (1), 7357, 2023 | 8 | 2023 |
Biological evaluation, molecular docking analyses, and ADME profiling of certain new quinazolinones as anti-colorectal agents NNE El-Sayed, NM Almaneai, A Ben Bacha, MK El-Ashrey, MI Al-Zaben, ... ACS omega 7 (22), 18443-18458, 2022 | 7 | 2022 |
A multidisciplinary approach to the antioxidant and hepatoprotective activities of Arbutus pavarii Pampan fruit; in vitro and in Vivo biological evaluations, and in silico … FA Elshibani, AD Alamami, HA Mohammed, RA Rasheed, RM El Sabban, ... Journal of Enzyme Inhibition and Medicinal Chemistry 39 (1), 2293639, 2024 | 6 | 2024 |
Discovery of pyrimidine-tethered benzothiazole derivatives as novel anti-tubercular agents towards multi- and extensively drug resistant Mycobacterium tuberculosis LR Hemeda, MA El Hassab, MA Abdelgawad, EF Khaleel, MM Abdel-Aziz, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2250575, 2023 | 6 | 2023 |
Roflumilast analogs with improved metabolic stability, plasma protein binding, and pharmacokinetic profile BA Moussa, AA El‐Zaher, MK El‐Ashrey, MA Fouad Drug Testing and Analysis 11 (6), 886-897, 2019 | 6 | 2019 |
Alanine racemase a promising Helicobacter pylori drug target inhibited by propanoic acid KA Ibrahim, MK El-Ashrey, MT Kashef, OM Helmy Microbes and Infection 25 (7), 105167, 2023 | 3 | 2023 |