Critical challenges and advances in recombinant adeno‐associated virus (rAAV) biomanufacturing Q Fu, A Polanco, YS Lee, S Yoon Biotechnology and Bioengineering 120 (9), 2601-2621, 2023 | 41 | 2023 |
Adventitious agent detection methods in bio-pharmaceutical applications with a focus on viruses, bacteria, and mycoplasma C Morris, YS Lee, S Yoon Current Opinion in Biotechnology 71, 105-114, 2021 | 19 | 2021 |
Transcriptomic features reveal molecular signatures associated with recombinant adeno‐associated virus production in HEK293 cells Y Wang, Q Fu, YS Lee, S Sha, S Yoon Biotechnology Progress 39 (4), e3346, 2023 | 18 | 2023 |
Design space determination to optimize DNA complexation and full capsid formation in transient rAAV manufacturing Q Fu, YS Lee, EA Green, Y Wang, SY Park, A Polanco, KH Lee, ... Biotechnology and Bioengineering 120 (11), 3148-3162, 2023 | 15 | 2023 |
Effect of iron addition on mAb productivity and oxidative stress in Chinese hamster ovary culture RJ Graham, A Mohammad, G Liang, Q Fu, B Kuang, A Polanco, YS Lee, ... Biotechnology Progress 37 (5), e3181, 2021 | 8 | 2021 |
Decoding cellular mechanism of recombinant adeno-associated virus (rAAV) and engineering host-cell factories toward intensified viral vector manufacturing Y Wang, Q Fu, SY Park, YS Lee, SY Park, DY Lee, S Yoon Biotechnology Advances, 108322, 2024 | 7 | 2024 |
Separation of full, empty, and partial adeno-associated virus capsids via anion-exchange chromatography with continuous recycling and accumulation YS Lee, J Lee, K Fang, GV Gee, B Rogers, D McNally, S Yoon Journal of Chromatography B, 124206, 2024 | 2 | 2024 |
Design space determination and process optimization of product quality attributes in transient rAAV manufacturing DMN Seongkyu Yoon, Qiang Fu, Yong Suk Lee, Erica A. Green, Yongdan Wang ... Cell Culture Engineering XVIII, 2023 | | 2023 |
Trace metal variability in culture media can impair CHO culture performance by enhancing mechanisms of oxidative stress S Yoon, A Polanco, Y Lee, R Graham, G Liang, A Mohammad American Chemical Society SciMeetings 1 (2), 2020 | | 2020 |