eIF2B conformation and assembly state regulate the integrated stress response M Schoof, M Boone*, L Wang*, R Lawrence*, A Frost, P Walter Elife 10, e65703, 2021 | 69 | 2021 |
Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction L Wang, A Myasnikov, X Pan, P Walter Elife 9, e54031, 2020 | 64 | 2020 |
Msp1/ATAD1 in Protein Quality Control and Regulation of Synaptic Activities L Wang, P Walter Annual Review of Cell and Developmental Biology 36, 141-164, 2020 | 45 | 2020 |
Antimicrobial activity of human islet amyloid polypeptides: An insight into amyloid peptides’ connection with antimicrobial peptides L Wang, Q Liu, JC Chen, YX Cui, B Zhou, YX Chen, YF Zhao, YM Li Biological chemistry 393 (7), 641-646, 2012 | 45 | 2012 |
Structural basis for avoidance of promutagenic DNA repair by MutY adenine DNA glycosylase L Wang, SJ Lee, GL Verdine Journal of Biological Chemistry 290 (28), 17096-17105, 2015 | 31 | 2015 |
Structural basis for the lesion-scanning mechanism of the MutY DNA glycosylase L Wang, S Chakravarthy, GL Verdine Journal of Biological Chemistry 292 (12), 5007-5017, 2017 | 29 | 2017 |
Conserved structural elements specialize ATAD1 as a membrane protein extraction machine L Wang*#, H Toutkoushian*, V Belyy, CY Kokontis, P Walter# eLife 11, e73941, 2022 | 17 | 2022 |
Viral evasion of the integrated stress response through antagonism of eIF2-P binding to eIF2B M Schoof*, L Wang*, JZ Cogan, RE Lawrence, M Boone, JD Wuerth, ... Nature communications 12 (1), 1-12, 2021 | 17 | 2021 |
A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response A Subramanian*, L Wang*, T Moss, M Voorhies, S Sangwan, E Stevenson, ... Nature Cell Biology, 1-16, 2023 | 13 | 2023 |
Reactivity of [(2-Phosphino) ethenyl] zirconocene Chloride toward CpM (CO) 3Cl (M= Mo, W): Formation of [(3-Phosphino) propenoyl] dicarbonyl (cyclopentadienyl) metal,{CpM (CO … X Yan, B Yu, L Wang, N Tang, C Xi Organometallics 28 (23), 6827-6830, 2009 | 9 | 2009 |
A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation M Boone*, L Wang*, R Lawrence, A Frost, P Walter#, M Schoof# eLife 11, e76171, 2022 | 8 | 2022 |
A Legionella toxin mimics tRNA and glycosylates the translation machinery to trigger a ribotoxic stress response. A Subramanian*, L Wang*, T Moss, M Voorhies, S Sangwan, E Stevenson, ... bioRxiv, 2022 | 3 | 2022 |
A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling RE Lawrence, SR Shoemaker, A Deal, S Sangwan, AA Anand, L Wang#, ... Nature Chemical Biology, 1-10, 2023 | | 2023 |
Structural Studies of the Bacterial MutY Adenine DNA Glycosylase and Its Human Homolog MUTYH L Wang Harvard University, 2016 | | 2016 |