| Making sense of G‐quadruplex and i‐motif functions in oncogene promoters TA Brooks, S Kendrick, L Hurley The FEBS journal 277 (17), 3459-3469, 2010 | 563 | 2010 |
| Targeting MYC expression through G-quadruplexes TA Brooks, LH Hurley Genes & cancer 1 (6), 641-649, 2010 | 369 | 2010 |
| The role of supercoiling in transcriptional control of MYC and its importance in molecular therapeutics TA Brooks, LH Hurley Nature Reviews Cancer 9 (12), 849-861, 2009 | 339 | 2009 |
| Demonstration that drug-targeted down-regulation of MYC in non-Hodgkins lymphoma is directly mediated through the promoter G-quadruplex RV Brown, FL Danford, V Gokhale, LH Hurley, TA Brooks Journal of Biological Chemistry 286 (47), 41018-41027, 2011 | 209 | 2011 |
| Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations TA Brooks, BT Hawkins, JD Huber, RD Egleton, TP Davis American Journal of Physiology-Heart and Circulatory Physiology 289 (2 …, 2005 | 181 | 2005 |
| Taxane-based reversal agents modulate drug resistance mediated by P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein T Brooks, H Minderman, KL O'Loughlin, P Pera, I Ojima, MR Baer, ... Molecular cancer therapeutics 2 (11), 1195-1205, 2003 | 168 | 2003 |
| Epigenetic modification, dehydration, and molecular crowding effects on the thermodynamics of i-motif structure formation from C-rich DNA YP Bhavsar-Jog, E Van Dornshuld, TA Brooks, GS Tschumper, ... Biochemistry 53 (10), 1586-1594, 2014 | 133 | 2014 |
| Anticancer activity and cellular repression of c-MYC by the G-quadruplex-stabilizing 11-piperazinylquindoline is not dependent on direct targeting of the G-quadruplex in the c … PVL Boddupally, S Hahn, C Beman, B De, TA Brooks, V Gokhale, ... Journal of medicinal chemistry 55 (13), 6076-6086, 2012 | 132 | 2012 |
| Tight junctions contain oligomeric protein assembly critical for maintaining blood–brain barrier integrity in vivo G McCaffrey, WD Staatz, CA Quigley, N Nametz, MJ Seelbach, ... Journal of neurochemistry 103 (6), 2540-2555, 2007 | 128 | 2007 |
| Increased MYC gene copy number correlates with increased mRNA levels in diffuse large B-cell lymphoma CJ Stasik, H Nitta, W Zhang, CH Mosher, JR Cook, RR Tubbs, JM Unger, ... Haematologica 95 (4), 597, 2010 | 125 | 2010 |
| Peripheral inflammatory hyperalgesia modulates morphine delivery to the brain: a role for P‐glycoprotein MJ Seelbach, TA Brooks, RD Egleton, TP Davis Journal of neurochemistry 102 (5), 1677-1690, 2007 | 121 | 2007 |
| Occludin oligomeric assembly at tight junctions of the blood‐brain barrier is disrupted by peripheral inflammatory hyperalgesia G McCaffrey, MJ Seelbach, WD Staatz, N Nametz, C Quigley, CR Campos, ... Journal of neurochemistry 106 (6), 2395-2409, 2008 | 93 | 2008 |
| Molecular cloning of the human platelet-derived growth factor receptor β (PDGFR-β) promoter and drug targeting of the G-quadruplex-forming region to repress PDGFR-β expression Y Qin, JS Fortin, D Tye, M Gleason-Guzman, TA Brooks, LH Hurley Biochemistry 49 (19), 4208-4219, 2010 | 83 | 2010 |
| Identification and characterization of a new G-quadruplex forming region within the kRAS promoter as a transcriptional regulator RK Morgan, H Batra, VC Gaerig, J Hockings, TA Brooks Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1859 (2), 235-245, 2016 | 78 | 2016 |
| Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023 H Minderman, TA Brooks, KL O’Loughlin, I Ojima, RJ Bernacki, MR Baer Cancer chemotherapy and pharmacology 53, 363-369, 2004 | 78 | 2004 |
| Effect of Interior Loop Length on the Thermal Stability and pKa of i-Motif DNA SM Reilly, RK Morgan, TA Brooks, RM Wadkins Biochemistry 54 (6), 1364-1370, 2015 | 77 | 2015 |
| Curcumin exposure modulates multiple pro-apoptotic and anti-apoptotic signaling pathways to antagonize acetaminophen-induced toxicity E Bulku, S J Stohs, L Cicero, T Brooks, H Halley, S D Ray Current neurovascular research 9 (1), 58-71, 2012 | 58 | 2012 |
| Design, synthesis and structure− activity relationships of novel taxane-based multidrug resistance reversal agents I Ojima, CP Borella, X Wu, PY Bounaud, CF Oderda, M Sturm, ML Miller, ... Journal of medicinal chemistry 48 (6), 2218-2228, 2005 | 57 | 2005 |
| Biphasic cytoarchitecture and functional changes in the BBB induced by chronic inflammatory pain TA Brooks, SM Ocheltree, MJ Seelbach, RA Charles, N Nametz, ... Brain research 1120 (1), 172-182, 2006 | 56 | 2006 |
| Storage length, storage temperature, and lean formulation influence the shelf-life and stability of traditionally packaged ground beef JN Martin, JC Brooks, TA Brooks, JF Legako, JD Starkey, SP Jackson, ... Meat Science 95 (3), 495-502, 2013 | 52 | 2013 |
