| Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study A Rauch, Z Kutalik, P Descombes, T Cai, J Di Iulio, T Mueller, M Bochud, ... Gastroenterology 138 (4), 1338-1345. e7, 2010 | 1487 | 2010 |
| MicroRNAs 103 and 107 regulate insulin sensitivity M Trajkovski, J Hausser, J Soutschek, B Bhat, A Akin, M Zavolan, ... Nature 474 (7353), 649-653, 2011 | 1157 | 2011 |
| Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA J Lucifora, Y Xia, F Reisinger, K Zhang, D Stadler, X Cheng, MF Sprinzl, ... Science 343 (6176), 1221-1228, 2014 | 1079 | 2014 |
| Defective STAT signaling by the leptin receptor in diabetic mice. N Ghilardi, S Ziegler, A Wiestner, R Stoffel, MH Heim, RC Skoda Proceedings of the National Academy of Sciences 93 (13), 6231-6235, 1996 | 1066 | 1996 |
| Interferon signaling and treatment outcome in chronic hepatitis C M Sarasin-Filipowicz, EJ Oakeley, FHT Duong, V Christen, L Terracciano, ... Proceedings of the National Academy of Sciences 105 (19), 7034-7039, 2008 | 803 | 2008 |
| Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c A Hagiwara, M Cornu, N Cybulski, P Polak, C Betz, F Trapani, ... Cell metabolism 15 (5), 725-738, 2012 | 640 | 2012 |
| Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification M Heim, UA Meyer The Lancet 336 (8714), 529-532, 1990 | 604 | 1990 |
| Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway MH Heim, M Kerr, GR Stark, JE Darnell Jr Science 267 (5202), 1347-1349, 1995 | 600 | 1995 |
| Human Arylamine N-Acetyltransferase Genes: Isolation, Chromosomal Localization, and Functional Expression M Blum, DM Grant, W McBride, M Heim, UA Meyer DNA and cell biology 9 (3), 193-203, 1990 | 582 | 1990 |
| Molecular mechanism of slow acetylation of drugs and carcinogens in humans. M Blum, A Demierre, DM Grant, M Heim, UA Meyer Proceedings of the National Academy of Sciences 88 (12), 5237-5241, 1991 | 505 | 1991 |
| The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota ML Balmer, E Slack, A De Gottardi, MAE Lawson, S Hapfelmeier, L Miele, ... Science translational medicine 6 (237), 237ra66-237ra66, 2014 | 481 | 2014 |
| Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients L Quagliata, MS Matter, S Piscuoglio, L Arabi, C Ruiz, A Procino, M Kovac, ... Hepatology 59 (3), 911-923, 2014 | 459 | 2014 |
| Organoid models of human liver cancers derived from tumor needle biopsies S Nuciforo, I Fofana, MS Matter, T Blumer, D Calabrese, T Boldanova, ... Cell reports 24 (5), 1363-1376, 2018 | 438 | 2018 |
| Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by … M Kagimoto, M Heim, K Kagimoto, T Zeugin, UA Meyer Journal of Biological Chemistry 265 (28), 17209-17214, 1990 | 418 | 1990 |
| The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus MH Heim Journal of Receptors and Signal Transduction 19 (1-4), 75-120, 1999 | 417 | 1999 |
| mTORC2 promotes tumorigenesis via lipid synthesis Y Guri, M Colombi, E Dazert, SK Hindupur, J Roszik, S Moes, P Jenoe, ... Cancer cell 32 (6), 807-823. e12, 2017 | 401 | 2017 |
| Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy M Sarasin-Filipowicz, J Krol, I Markiewicz, MH Heim, W Filipowicz Nature medicine 15 (1), 31-33, 2009 | 397 | 2009 |
| Innate and adaptive immune responses in HCV infections MH Heim, R Thimme Journal of hepatology 61 (1), S14-S25, 2014 | 388 | 2014 |
| Expression of hepatitis C virus proteins inhibits signal transduction through the Jak-STAT pathway MH Heim, D Moradpour, HE Blum Journal of Virology 73 (10), 8469-8475, 1999 | 369 | 1999 |
| Genotype 3 is associated with accelerated fibrosis progression in chronic hepatitis C PY Bochud, T Cai, K Overbeck, M Bochud, JF Dufour, B Müllhaupt, ... Journal of hepatology 51 (4), 655-666, 2009 | 363 | 2009 |
