| RNA-programmed genome editing in human cells M Jinek, A East, A Cheng, S Lin, E Ma, J Doudna elife 2, e00471, 2013 | 3017 | 2013 |
| High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity V Pattanayak, S Lin, JP Guilinger, E Ma, JA Doudna, DR Liu Nature biotechnology 31 (9), 839-843, 2013 | 1957 | 2013 |
| Structures of Cas9 endonucleases reveal RNA-mediated conformational activation M Jinek, F Jiang, DW Taylor, SH Sternberg, E Kaya, E Ma, C Anders, ... Science 343 (6176), 1247997, 2014 | 1654 | 2014 |
| Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery S Lin, BT Staahl, RK Alla, JA Doudna elife 3, e04766, 2014 | 1445 | 2014 |
| Generation of knock-in primary human T cells using Cas9 ribonucleoproteins K Schumann, S Lin, E Boyer, DR Simeonov, M Subramaniam, RE Gate, ... Proceedings of the National Academy of Sciences 112 (33), 10437-10442, 2015 | 865 | 2015 |
| Studies on the immuno-modulating and anti-tumor activities of Ganoderma lucidum (Reishi) polysaccharides HS Chen, YF Tsai, S Lin, CC Lin, KH Khoo, CH Lin, CH Wong Bioorganic & medicinal chemistry 12 (21), 5595-5601, 2004 | 262 | 2004 |
| Precise and heritable genome editing in evolutionarily diverse nematodes using TALENs and CRISPR/Cas9 to engineer insertions and deletions TW Lo, CS Pickle, S Lin, EJ Ralston, M Gurling, CM Schartner, Q Bian, ... Genetics 195 (2), 331-348, 2013 | 231 | 2013 |
| Biotin synthesis begins by hijacking the fatty acid synthetic pathway S Lin, RE Hanson, JE Cronan Nature chemical biology 6 (9), 682-688, 2010 | 230 | 2010 |
| Closing in on complete pathways of biotin biosynthesis S Lin, JE Cronan Molecular BioSystems 7 (6), 1811-1821, 2011 | 174 | 2011 |
| Escherichia coli O86 O-Antigen Biosynthetic Gene Cluster and Stepwise Enzymatic Synthesis of Human Blood Group B Antigen Tetrasaccharide W Yi, J Shao, L Zhu, M Li, M Singh, Y Lu, S Lin, H Li, K Ryu, J Shen, ... Journal of the American Chemical Society 127 (7), 2040-2041, 2005 | 135 | 2005 |
| Synthesis of α-galactosyl ceramide and the related glycolipids for evaluation of their activities on mouse splenocytes GT Fan, Y Pan, KC Lu, YP Cheng, WC Lin, S Lin, CH Lin, CH Wong, ... Tetrahedron 61 (7), 1855-1862, 2005 | 111 | 2005 |
| Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis V Agarwal, S Lin, T Lukk, SK Nair, JE Cronan Proceedings of the National Academy of Sciences 109 (43), 17406-17411, 2012 | 100 | 2012 |
| Analysis of molecular inversion probe performance for allele copy number determination Y Wang, M Moorhead, G Karlin-Neumann, NJ Wang, J Ireland, S Lin, ... Genome biology 8, 1-14, 2007 | 87 | 2007 |
| Enhanced NK-92 cytotoxicity by CRISPR genome engineering using Cas9 ribonucleoproteins RS Huang, HA Shih, MC Lai, YJ Chang, S Lin Frontiers in immunology 11, 1008, 2020 | 76 | 2020 |
| The BioC O-methyltransferase catalyzes methyl esterification of malonyl-acyl carrier protein, an essential step in biotin synthesis S Lin, JE Cronan Journal of Biological Chemistry 287 (44), 37010-37020, 2012 | 70 | 2012 |
| A robust platform for expansion and genome editing of primary human natural killer cells RS Huang, MC Lai, HA Shih, S Lin Journal of Experimental Medicine 218 (3), e20201529, 2021 | 63 | 2021 |
| Biosynthesis of complex indole alkaloids: elucidation of the concise pathway of okaramines CY Lai, IW Lo, RT Hewage, YC Chen, CT Chen, CF Lee, S Lin, MC Tang, ... Angewandte Chemie 129 (32), 9606-9610, 2017 | 58 | 2017 |
| Humanized COVID‐19 decoy antibody effectively blocks viral entry and prevents SARS‐CoV‐2 infection KY Huang, MS Lin, TC Kuo, CL Chen, CC Lin, YC Chou, TL Chao, ... EMBO molecular medicine 13 (1), e12828, 2021 | 57 | 2021 |
| DNA-free CRISPR-Cas9 gene editing of wild tetraploid tomato Solanum peruvianum using protoplast regeneration CS Lin, CT Hsu, YH Yuan, PX Zheng, FH Wu, QW Cheng, YL Wu, TL Wu, ... Plant physiology 188 (4), 1917-1930, 2022 | 54 | 2022 |
| Synthesis of the α, ω-dicarboxylic acid precursor of biotin by the canonical fatty acid biosynthetic pathway JE Cronan, S Lin Current opinion in chemical biology 15 (3), 407-413, 2011 | 48 | 2011 |
