An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity W Guo, Y Chen, X Zhou, A Kar, P Ray, X Chen, EJ Rao, M Yang, H Ye, ... Nature structural & molecular biology 18 (7), 822-830, 2011 | 353 | 2011 |
DSCAM functions as a netrin receptor in commissural axon pathfinding G Liu, W Li, L Wang, A Kar, KL Guan, Y Rao, JY Wu Proceedings of the National Academy of Sciences 106 (8), 2951-2956, 2009 | 192 | 2009 |
Pre-mRNA splicing and retinitis pigmentosa D Mordes, X Luo, A Kar, D Kuo, L Xu, K Fushimi, G Yu, P Sternberg Jr, ... Molecular vision 12, 1259, 2006 | 171 | 2006 |
Axonal G3BP1 stress granule protein limits axonal mRNA translation and nerve regeneration PK Sahoo, SJ Lee, PB Jaiswal, S Alber, AN Kar, S Miller-Randolph, ... Nature communications 9 (1), 3358, 2018 | 168 | 2018 |
Up-regulation of the proapoptotic caspase 2 splicing isoform by a candidate tumor suppressor, RBM5 K Fushimi, P Ray, A Kar, L Wang, LC Sutherland, JY Wu Proceedings of the National Academy of Sciences 105 (41), 15708-15713, 2008 | 163 | 2008 |
The functional organization of axonal mRNA transport and translation I Dalla Costa, CN Buchanan, MD Zdradzinski, PK Sahoo, TP Smith, ... Nature Reviews Neuroscience 22 (2), 77-91, 2021 | 157 | 2021 |
Progranulin promotes neurite outgrowth and neuronal differentiation by regulating GSK-3β X Gao, AP Joselin, L Wang, A Kar, P Ray, A Bateman, AM Goate, JY Wu Protein & cell 1, 552-562, 2010 | 153 | 2010 |
RNA Helicase p68 (DDX5) Regulates tau Exon 10 Splicing by Modulating a Stem-Loop Structure at the 5′ Splice Site A Kar, K Fushimi, X Zhou, P Ray, C Shi, X Chen, Z Liu, S Chen, JY Wu Molecular and cellular biology 31 (9), 1812-1821, 2011 | 142 | 2011 |
MicroRNA-338 regulates the axonal expression of multiple nuclear-encoded mitochondrial mRNAs encoding subunits of the oxidative phosphorylation machinery A Aschrafi, AN Kar, O Natera-Naranjo, MA MacGibeny, AE Gioio, ... Cellular and Molecular Life Sciences 69, 4017-4027, 2012 | 117 | 2012 |
Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition AL Kalinski, AN Kar, J Craver, AP Tosolini, JN Sleigh, SJ Lee, ... Journal of Cell Biology 218 (6), 1871-1890, 2019 | 103 | 2019 |
Intra-axonal synthesis of eukaryotic translation initiation factors regulates local protein synthesis and axon growth in rat sympathetic neurons AN Kar, MA MacGibeny, NM Gervasi, AE Gioio, BB Kaplan Journal of Neuroscience 33 (17), 7165-7174, 2013 | 81 | 2013 |
Tau alternative splicing and frontotemporal dementia A Kar, D Kuo, R He, J Zhou, JY Wu Alzheimer Disease & Associated Disorders 19, S29-S36, 2005 | 80 | 2005 |
SRp54 (SFRS11), a regulator for tau exon 10 alternative splicing identified by an expression cloning strategy JY Wu, A Kar, D Kuo, B Yu, N Havlioglu Molecular and cellular biology 26 (18), 6739-6747, 2006 | 79 | 2006 |
RBM4 interacts with an intronic element and stimulates tau exon 10 inclusion A Kar, N Havlioglu, WY Tarn, JY Wu Journal of Biological Chemistry 281 (34), 24479-24488, 2006 | 76 | 2006 |
MicroRNAs in the axon and presynaptic nerve terminal BB Kaplan, AN Kar, AE Gioio, A Aschrafi Frontiers in cellular neuroscience 7, 126, 2013 | 68 | 2013 |
Local translation of ATP synthase subunit 9 mRNA alters ATP levels and the production of ROS in the axon O Natera-Naranjo, AN Kar, A Aschrafi, NM Gervasi, MA Macgibeny, ... Molecular and Cellular Neuroscience 49 (3), 263-270, 2012 | 62 | 2012 |
PSF suppresses tau exon 10 inclusion by interacting with a stem-loop structure downstream of exon 10 P Ray, A Kar, K Fushimi, N Havlioglu, X Chen, JY Wu Journal of Molecular Neuroscience 45, 453-466, 2011 | 60 | 2011 |
The local expression and trafficking of tyrosine hydroxylase mRNA in the axons of sympathetic neurons NM Gervasi, SS Scott, A Aschrafi, J Gale, SN Vohra, MA MacGibeny, ... Rna 22 (6), 883-895, 2016 | 58 | 2016 |
Expanding axonal transcriptome brings new functions for axonally synthesized proteins in health and disease AN Kar, SJ Lee, JL Twiss The Neuroscientist 24 (2), 111-129, 2018 | 51 | 2018 |
Dysbiosis-associated enteric glial cell immune-activation and redox imbalance modulate tight junction protein expression in gulf war illness pathology D Kimono, S Sarkar, M Albadrani, R Seth, D Bose, A Mondal, Y Li, AN Kar, ... Frontiers in Physiology 10, 1229, 2019 | 42 | 2019 |