Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes P Yang, H Kanki, B Drolet, T Yang, J Wei, PC Viswanathan, SH Hohnloser, ... Circulation 105 (16), 1943-1948, 2002 | 697 | 2002 |
Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans H Watanabe, TT Koopmann, S Le Scouarnec, T Yang, CR Ingram, ... The Journal of clinical investigation 118 (6), 2260-2268, 2008 | 589 | 2008 |
Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular … BC Knollmann, N Chopra, T Hlaing, B Akin, T Yang, K Ettensohn, ... The Journal of clinical investigation 116 (9), 2510-2520, 2006 | 533 | 2006 |
Extracellular Potassium Modulation of Drug Block of IKr Implications for Torsade de Pointes and Reverse Use-Dependence T Yang, DM Roden Circulation 93 (3), 407-411, 1996 | 532 | 1996 |
Blocking Scn10a Channels in Heart Reduces Late Sodium Current and Is Antiarrhythmic T Yang, TC Atack, DM Stroud, W Zhang, L Hall, DM Roden Circulation research 111 (3), 322-332, 2012 | 366* | 2012 |
Cardiovascular toxicities associated with ibrutinib JE Salem, A Manouchehri, M Bretagne, B Lebrun-Vignes, JD Groarke, ... Journal of the American College of Cardiology 74 (13), 1667-1678, 2019 | 250 | 2019 |
Ibutilide, a Methanesulfonanilide Antiarrhythmic, Is a Potent Blocker of the Rapidly Activating Delayed Rectifier K+ Current (IKr) in AT-1 Cells: Concentration-, Time … T Yang, DJ Snyders, DM Roden Circulation 91 (6), 1799-1806, 1995 | 230 | 1995 |
Rapid Inactivation Determines the Rectification and [K+]o Dependence of the Rapid Component of the Delayed Rectifier K+ Current in Cardiac Cells T Yang, DJ Snyders, DM Roden Circulation Research 80 (6), 782-789, 1997 | 214 | 1997 |
Drug block of I Kr: model systems and relevance to human arrhythmias T Yang, D Snyders, DM Roden Journal of cardiovascular pharmacology 38 (5), 737-744, 2001 | 200 | 2001 |
Rate-dependent class III antiarrhythmic action, negative chronotropy, and positive inotropy of a novel Ik blocking drug, UK-68,798: potent in guinea pig but no effect in rat … PM Tande, H Bjørnstad, T Yang, H Refsum Journal of cardiovascular pharmacology 16 (3), 401-410, 1990 | 186 | 1990 |
Prospective, population-based long QT molecular autopsy study of postmortem negative sudden death in 1 to 40 year olds JR Skinner, J Crawford, W Smith, A Aitken, D Heaven, CA Evans, I Hayes, ... Heart Rhythm 8 (3), 412-419, 2011 | 184 | 2011 |
Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation–contraction coupling, and cardiac arrhythmias N Chopra, T Yang, P Asghari, ED Moore, S Huke, B Akin, RA Cattolica, ... Proceedings of the National Academy of Sciences 106 (18), 7636-7641, 2009 | 181 | 2009 |
Screening for Acute IKr Block Is Insufficient to Detect Torsades de Pointes Liability: Role of Late Sodium Current T Yang, YW Chun, DM Stroud, JD Mosley, BC Knollmann, C Hong, ... Circulation 130 (3), 224-234, 2014 | 177 | 2014 |
Modest Reductions of Cardiac Calsequestrin Increase Sarcoplasmic Reticulum Ca2+ Leak Independent of Luminal Ca2+ and Trigger Ventricular Arrhythmias in … N Chopra, PJ Kannankeril, T Yang, T Hlaing, I Holinstat, K Ettensohn, ... Circulation research 101 (6), 617-626, 2007 | 168 | 2007 |
Striking In Vivo Phenotype of a Disease-Associated Human SCN5A Mutation Producing Minimal Changes in Vitro H Watanabe, T Yang, DM Stroud, JS Lowe, L Harris, TC Atack, DW Wang, ... Circulation 124 (9), 1001-1011, 2011 | 165 | 2011 |
Potassium current antagonist properties and proarrhythmic consequences of quinolone antibiotics ME Anderson, A Mazur, T Yang, DM Roden The Journal of Pharmacology and Experimental Therapeutics 296 (3), 808-812, 2001 | 144 | 2001 |
Protecting the heart against arrhythmias: potassium current physiology and repolarization reserve DM Roden, T Yang Circulation 112 (10), 1376-1378, 2005 | 134 | 2005 |
Role of common and rare variants in SCN10A: results from the Brugada syndrome QRS locus gene discovery collaborative study ER Behr, E Savio-Galimberti, J Barc, AG Holst, E Petropoulou, BP Prins, ... Cardiovascular research 106 (3), 520-529, 2015 | 131 | 2015 |
Unmasking of Brugada syndrome by lithium D Darbar, T Yang, K Churchwell, AAM Wilde, DM Roden Circulation 112 (11), 1527-1531, 2005 | 131 | 2005 |
Azithromycin causes a novel proarrhythmic syndrome Z Yang, JK Prinsen, KR Bersell, W Shen, L Yermalitskaya, T Sidorova, ... Circulation: Arrhythmia and Electrophysiology 10 (4), e003560, 2017 | 115 | 2017 |