Retroelement-guided protein diversification abounds in vast lineages of Bacteria and Archaea BG Paul, D Burstein, CJ Castelle, S Handa, D Arambula, E Czornyj, ... Nature microbiology 2 (6), 1-7, 2017 | 78 | 2017 |
Targeted diversity generation by intraterrestrial archaea and archaeal viruses BG Paul, SC Bagby, E Czornyj, D Arambula, S Handa, A Sczyrba, ... Nature communications 6 (1), 6585, 2015 | 69 | 2015 |
Diversity-generating retroelements: natural variation, classification and evolution inferred from a large-scale genomic survey L Wu, M Gingery, M Abebe, D Arambula, E Czornyj, S Handa, H Khan, ... Nucleic acids research 46 (1), 11-24, 2018 | 62 | 2018 |
Mechanistic binding insights for 1-deoxy-d-Xylulose-5-Phosphate synthase, the enzyme catalyzing the first reaction of isoprenoid biosynthesis in the malaria-causing protists … MR Battistini, C Shoji, S Handa, L Breydo, DJ Merkler Protein expression and purification 120, 16-27, 2016 | 28 | 2016 |
Thiamin Diphosphate Activation in 1-Deoxy-d-xylulose 5-Phosphate Synthase: Insights into the Mechanism and Underlying Intermolecular Interactions JK White, S Handa, SL Vankayala, DJ Merkler, HL Woodcock The journal of physical chemistry B 120 (37), 9922-9934, 2016 | 25 | 2016 |
Template-assisted synthesis of adenine-mutagenized cDNA by a retroelement protein complex S Handa, Y Jiang, S Tao, R Foreman, RF Schinazi, JF Miller, P Ghosh Nucleic acids research 46 (18), 9711-9725, 2018 | 24 | 2018 |
Conservation of the C-type lectin fold for accommodating massive sequence variation in archaeal diversity-generating retroelements S Handa, BG Paul, JF Miller, DL Valentine, P Ghosh BMC structural biology 16, 1-9, 2016 | 22 | 2016 |
Production of recombinant 1-deoxy-d-xylulose-5-phosphate synthase from Plasmodium vivax in Escherichia coli S Handa, D Ramamoorthy, TJ Spradling, WC Guida, JH Adams, ... FEBS Open Bio 3, 124-129, 2013 | 22 | 2013 |
Mechanistic and structural analysis of a Drosophila melanogaster enzyme, arylalkylamine N-acetyltransferase like 7, an enzyme that catalyzes the formation of N … DR Dempsey, KA Jeffries, S Handa, AM Carpenter, S Rodriguez-Ospina, ... Biochemistry 54 (16), 2644-2658, 2015 | 20 | 2015 |
Mechanistic studies of 1-deoxy-d-xylulose-5-phosphate synthase from Deinococcus radiodurans S Handa, DR Dempsey, D Ramamoorthy, N Cook, WC Guida, ... Biochemistry & molecular biology journal 4 (1), 2018 | 15 | 2018 |
Crystal structure of a Thermus aquaticus diversity-generating retroelement variable protein S Handa, KL Shaw, P Ghosh PLoS One 14 (1), e0205618, 2019 | 12 | 2019 |
Determinants of adenine-mutagenesis in diversity-generating retroelements S Handa, A Reyna, T Wiryaman, P Ghosh Nucleic acids research 49 (2), 1033-1045, 2021 | 9 | 2021 |
Production of the catalytic core of human peptidylglycine α-hydroxylating monooxygenase (hPHMcc) in Escherichia coli S Handa, TJ Spradling, DR Dempsey, DJ Merkler Protein expression and purification 84 (1), 9-13, 2012 | 8 | 2012 |
N-Acylethanolamines as novel alcohol dehydrogenase 3 substrates M Ivkovic, DR Dempsey, S Handa, JH Hilton, EW Lowe Jr, DJ Merkler Archives of biochemistry and biophysics 506 (2), 157-164, 2011 | 7 | 2011 |
Plasmodium vivax 1-deoxy-D-xylulose-5-phosphate synthase: Homology Modeling, Domain Swapping, and Virtual Screening D Ramamoorthy, S Handa, D Merkler, W Guida J Data Mining Genomics Proteomics S 1, 2153-0602, 2014 | 4 | 2014 |
Structural and biochemical characterization of Leptospira interrogans Lsa45 reveals a penicillin-binding protein with esterase activity JC Santos, S Handa, LGV Fernandes, L Bleicher, CA Gandin, ... Process Biochemistry 125, 141-153, 2023 | 2 | 2023 |
Targeting 1-Deoxy-D-xylulose-5-Phosphate Synthase (DXS) in Plasmodium Species for New Generation of Antimalarial S Handa Mol Biol 5 (175), 2, 2016 | 2 | 2016 |
Structural Requirements for Reverse Transcription by a Diversity-generating Retroelement S Handa, T Biswas, J Chakraborty, G Ghosh, BG Paul, P Ghosh bioRxiv, 2023.10. 23.563531, 2023 | 1 | 2023 |
Determinants of Selective Fidelity in Diversity-Generating Retroelements S Handa, A Reyna, T Wiryaman, P Ghosh bioRxiv, 2020 | 1 | 2020 |
Retroelement-guided protein diversification abounds in vast lineages of Bacteria and BG Paul, D Burstein, CJ Castelle, S Handa, D Arambula, E Czornyj, ... Archaea 6, 1-7, 2017 | 1 | 2017 |