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Grace A. Chappell
Grace A. Chappell
ICF International
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Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: A systematic literature review
G Chappell, IP Pogribny, KZ Guyton, I Rusyn
Mutation Research/Reviews in Mutation Research 768, 27-45, 2016
1762016
A chemical–biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives
FA Grimm, Y Iwata, O Sirenko, GA Chappell, FA Wright, DM Reif, ...
Green chemistry 18 (16), 4407-4419, 2016
912016
Review of transcriptomic responses to hexavalent chromium exposure in lung cells supports a role of epigenetic mediators in carcinogenesis
JE Rager, M Suh, GA Chappell, CM Thompson, DM Proctor
Toxicology letters 305, 40-50, 2019
782019
Assessment of the mode of action underlying the effects of GenX in mouse liver and implications for assessing human health risks
GA Chappell, CM Thompson, JC Wolf, JM Cullen, JE Klaunig, LC Haws
Toxicologic pathology 48 (3), 494-508, 2020
552020
Benchmark dose modeling estimates of the concentrations of inorganic arsenic that induce changes to the neonatal transcriptome, proteome, and epigenome in a pregnancy cohort
JE Rager, SS Auerbach, GA Chappell, E Martin, CM Thompson, RC Fry
Chemical research in toxicology 30 (10), 1911-1920, 2017
552017
Inbreeding Depression and Inbreeding Avoidance in a Natural Population of Guppies (Poecilia reticulata)
AM Johnson, G Chappell, AC Price, F Helen Rodd, R Olendorf, ...
Ethology 116 (5), 448-457, 2010
552010
Genetic and epigenetic changes in fibrosis‐associated hepatocarcinogenesis in mice
G Chappell, K Kutanzi, T Uehara, V Tryndyak, HH Hong, M Hoenerhoff, ...
International Journal of Cancer 134 (12), 2778-2788, 2014
462014
Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation
GR Keele, BC Quach, JW Israel, GA Chappell, L Lewis, A Safi, JM Simon, ...
PLoS genetics 16 (1), e1008537, 2020
452020
In vitro screening for population variability in toxicity of pesticide-containing mixtures
N Abdo, BA Wetmore, GA Chappell, D Shea, FA Wright, I Rusyn
Environment international 85, 147-155, 2015
442015
A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates
M Suh, D Proctor, G Chappell, J Rager, C Thompson, S Borghoff, L Finch, ...
Toxicology 402, 50-67, 2018
412018
Assessment of the biochemical pathways for acetaminophen toxicity: Implications for its carcinogenic hazard potential
H Jaeschke, FJ Murray, AD Monnot, D Jacobson-Kram, SM Cohen, ...
Regulatory Toxicology and Pharmacology 120, 104859, 2021
332021
Epigenetic events determine tissue-specific toxicity of inhalational exposure to the genotoxic chemical 1, 3-butadiene in male C57BL/6J mice
G Chappell, T Kobets, B O’Brien, N Tretyakova, D Sangaraju, O Kosyk, ...
Toxicological Sciences 142 (2), 375-384, 2014
332014
Tissue-and strain-specific effects of a genotoxic carcinogen 1, 3-butadiene on chromatin and transcription
JW Israel, GA Chappell, JM Simon, S Pott, A Safi, L Lewis, P Cotney, ...
Mammalian genome 29, 153-167, 2018
272018
Benefit-risk analysis for foods (BRAFO): evaluation of exposure to dietary nitrates
DS Wikoff, C Thompson, J Rager, G Chappell, S Fitch, C Doepker
Food and chemical toxicology 120, 709-723, 2018
252018
Variation in DNA-damage responses to an inhalational carcinogen (1, 3-butadiene) in relation to strain-specific differences in chromatin accessibility and gene transcription …
GA Chappell, JW Israel, JM Simon, S Pott, A Safi, K Eklund, KG Sexton, ...
Environmental Health Perspectives 125 (10), 107006, 2017
252017
A mouse model of alcoholic liver fibrosis-associated acute kidney injury identifies key molecular pathways
S Furuya, GA Chappell, Y Iwata, T Uehara, Y Kato, H Kono, R Bataller, ...
Toxicology and applied pharmacology 310, 129-139, 2016
252016
Updated systematic assessment of human, animal and mechanistic evidence demonstrates lack of human carcinogenicity with consumption of aspartame
SJ Borghoff, SS Cohen, X Jiang, IA Lea, WD Klaren, GA Chappell, JK Britt, ...
Food and Chemical Toxicology 172, 113549, 2023
222023
Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: An update of a systematic literature review
S Goodman, G Chappell, KZ Guyton, IP Pogribny, I Rusyn
Mutation Research/reviews in Mutation Research 789, 108408, 2022
212022
An adverse outcome pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events
DM Proctor, M Suh, G Chappell, SJ Borghoff, CM Thompson, K Wiench, ...
Regulatory Toxicology and Pharmacology 96, 30-40, 2018
202018
Assessment of mechanistic data for hexavalent chromium-induced rodent intestinal cancer using the key characteristics of carcinogens
GA Chappell, DS Wikoff, CM Thompson
Toxicological Sciences 180 (1), 38-50, 2021
192021
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