| c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun X Xie, TS Kaoud, R Edupuganti, T Zhang, T Kogawa, Y Zhao, ... Oncogene 36 (18), 2599-2608, 2017 | 94 | 2017 |
| Definition of a novel feed-forward mechanism for glycolysis-HIF1α signaling in hypoxic tumors highlights aldolase A as a therapeutic target G Grandjean, PR de Jong, BP James, MY Koh, R Lemos, J Kingston, ... Cancer research 76 (14), 4259-4269, 2016 | 79 | 2016 |
| Synthesis and biological evaluation of pyrido [2, 3-d] pyrimidine-2, 4-dione derivatives as eEF-2K inhibitors R Edupuganti, Q Wang, CDJ Tavares, CA Chitjian, JL Bachman, P Ren, ... Bioorganic & medicinal chemistry 22 (17), 4910-4916, 2014 | 75 | 2014 |
| Asymmetric Total Synthesis of (S)-(+)-Cocaine and the First Synthesis of Cocaine C-1 Analogs from N-Sulfinyl β-Amino Ester Ketals FA Davis, N Theddu, R Edupuganti Organic letters 12 (18), 4118-4121, 2010 | 54 | 2010 |
| Conformational preferences of substrates for human prolyl 4-hydroxylase KL Gorres, R Edupuganti, GR Krow, RT Raines Biochemistry 47 (36), 9447-9455, 2008 | 49 | 2008 |
| A c-Jun N-terminal kinase inhibitor, JNK-IN-8, sensitizes triple negative breast cancer cells to lapatinib ND Ebelt, TS Kaoud, R Edupuganti, S Van Ravenstein, KN Dalby, ... Oncotarget 8 (62), 104894, 2017 | 42 | 2017 |
| Discovery of a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth R Edupuganti, JM Taliaferro, Q Wang, X Xie, EJ Cho, F Vidhu, P Ren, ... Bioorganic & medicinal chemistry 25 (9), 2609-2616, 2017 | 38 | 2017 |
| High-throughput screens for eEF-2 kinase AK Devkota, M Warthaka, R Edupuganti, CDJ Tavares, WH Johnson, ... Journal of biomolecular screening 19 (3), 445-452, 2014 | 36 | 2014 |
| Asymmetric Synthesis of Substituted Homotropinones from N-Sulfinyl β-Amino Ketone Ketals. (−)-Euphococcinine and (−)-Adaline FA Davis, R Edupuganti Organic Letters 12 (4), 848-851, 2010 | 31 | 2010 |
| Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo TS Kaoud, WH Johnson, ND Ebelt, A Piserchio, D Zamora-Olivares, ... Nature Communications 10 (1), 5232, 2019 | 28 | 2019 |
| Reversible covalent inhibition of eEF‐2K by carbonitriles AK Devkota, R Edupuganti, C Yan, Y Shi, J Jose, Q Wang, TS Kaoud, ... ChemBioChem 15 (16), 2435-2442, 2014 | 28 | 2014 |
| Exploring naphthyl-carbohydrazides as inhibitors of influenza A viruses S Barman, L You, R Chen, V Codrea, G Kago, R Edupuganti, J Robertus, ... European journal of medicinal chemistry 71, 81-90, 2014 | 28 | 2014 |
| Synthesis and applications of masked oxo-sulfinamides in asymmetric synthesis R Edupuganti, FA Davis Organic & Biomolecular Chemistry 10 (26), 5021-5031, 2012 | 28 | 2012 |
| Mechanistic studies on covalent assemblies of metal-mediated hemi-aminal ethers HH Jo, R Edupuganti, L You, KN Dalby, EV Anslyn Chemical science 6 (1), 158-164, 2015 | 27 | 2015 |
| Serotonin analogues as inhibitors of breast cancer cell growth J Jose, CDJ Tavares, ND Ebelt, A Lodi, R Edupuganti, X Xie, AK Devkota, ... ACS Medicinal Chemistry Letters 8 (10), 1072-1076, 2017 | 25 | 2017 |
| Using docking and alchemical free energy approach to determine the binding mechanism of eEF2K inhibitors and prioritizing the compound synthesis Q Wang, R Edupuganti, CDJ Tavares, KN Dalby, P Ren Frontiers in Molecular Biosciences 2, 9, 2015 | 19 | 2015 |
| Synthesis of Conformationally Constrained 5-Fluoro- and 5-Hydroxymethanopyrrolidines. Ring-Puckered Mimics of Gauche- and Anti-3-Fluoro- and 3 … GR Krow, R Edupuganti, D Gandla, F Yu, M Sender, PE Sonnet, MJ Zdilla, ... The Journal of Organic Chemistry 76 (10), 3626-3634, 2011 | 18 | 2011 |
| Quantification of a pharmacodynamic ERK end point in melanoma cell lysates: toward personalized precision medicine M Warthaka, CH Adelmann, TS Kaoud, R Edupuganti, C Yan, ... ACS medicinal chemistry letters 6 (1), 47-52, 2015 | 17 | 2015 |
| Synthesis of 5-Fluoro- and 5-Hydroxymethanoprolines via Lithiation of N-BOC-methanopyrrolidines. Constrained Cγ-Exo and Cγ-Endo Flp and Hyp Conformer … GR Krow, MD Shoulders, R Edupuganti, D Gandla, F Yu, PE Sonnet, ... The Journal of Organic Chemistry 77 (12), 5331-5344, 2012 | 16 | 2012 |
| Computational and experimental studies of inhibitor Design for Aldolase A R Qi, B Walker, Z Jing, M Yu, G Stancu, R Edupuganti, KN Dalby, P Ren The Journal of Physical Chemistry B 123 (28), 6034-6041, 2019 | 10 | 2019 |
Tamer S KaoudThe University of Texas at Austinutexas.edu üzerinde doğrulanmış e-posta adresine sahip