| Molecular mechanism of down-regulating adipogenic transcription factors in 3T3-L1 adipocyte cells by bioactive anti-adipogenic compounds A Guru, PK Issac, M Velayutham, NT Saraswathi, A Arshad, J Arockiaraj Molecular Biology Reports 48 (1), 743-761, 2021 | 89 | 2021 |
| Oxidative stress induced antioxidant and neurotoxicity demonstrated in vivo zebrafish embryo or larval model and their normalization due to morin showing therapeutic implications PK Issac, A Guru, M Velayutham, R Pachaiappan, MV Arasu, NA Al-Dhabi, ... Life sciences 283, 119864, 2021 | 87 | 2021 |
| Intracellular ROS scavenging and antioxidant regulation of WL15 from cysteine and glycine-rich protein 2 demonstrated in zebrafish in vivo model A Guru, C Lite, AJ Freddy, PK Issac, M Pasupuleti, NT Saraswathi, ... Developmental & Comparative Immunology 114, 103863, 2021 | 80 | 2021 |
| Embryonic exposure to butylparaben and propylparaben induced developmental toxicity and triggered anxiety‐like neurobehavioral response associated with oxidative stress and … C Lite, A Guru, M Juliet, J Arockiaraj Environmental Toxicology 37 (8), 1988-2004, 2022 | 57 | 2022 |
| Amelioration of acrylamide induced neurotoxicity by benzo [b] thiophene analogs via glutathione redox dynamics in zebrafish larvae B Haridevamuthu, T Manjunathan, A Guru, CRW Alphonse, S Boopathi, ... Brain Research 1788, 147941, 2022 | 56 | 2022 |
| Hydroxyl containing benzo [b] thiophene analogs mitigates the acrylamide induced oxidative stress in the zebrafish larvae by stabilizing the glutathione redox cycle B Haridevamuthu, T Manjunathan, A Guru, RS Kumar, R Rajagopal, ... Life Sciences 298, 120507, 2022 | 51 | 2022 |
| 6‐Gingerol and semisynthetic 6‐gingerdione counteract oxidative stress induced by ros in zebrafish T Manjunathan, A Guru, J Arokiaraj, P Gopinath Chemistry & Biodiversity 18 (12), e2100650, 2021 | 50 | 2021 |
| Neuroprotective effect of Biochanin a against Bisphenol A-induced prenatal neurotoxicity in zebrafish by modulating oxidative stress and locomotory defects B Haridevamuthu, A Guru, R Murugan, G Sudhakaran, R Pachaiappan, ... Neuroscience Letters 790, 136889, 2022 | 46 | 2022 |
| Reverse pharmacology of Nimbin-N2 attenuates alcoholic liver injury and promotes the hepatoprotective dual role of improving lipid metabolism and downregulating the levels of … G Sudhakaran, P Prathap, A Guru, B Haridevamuthu, R Murugan, ... Molecular and cellular biochemistry 477 (10), 2387-2401, 2022 | 44 | 2022 |
| Anti‐inflammatory role demonstrated both in vitro and in vivo models using nonsteroidal tetranortriterpenoid, Nimbin (N1) and its analogs (N2 and N3) that alleviate the … G Sudhakaran, P Prathap, A Guru, R Rajesh, S Sathish, T Madhavan, ... Cell Biology International 46 (5), 771-791, 2022 | 44 | 2022 |
| Lipid-lowering and antioxidant activity of RF13 peptide from vacuolar protein sorting-associated protein 26B (VPS26B) by modulating lipid metabolism and oxidative stress in HFD … A Guru, M Velayutham, J Arockiaraj International Journal of Peptide Research and Therapeutics 28 (2), 74, 2022 | 44 | 2022 |
| Tryptophan-tagged peptide from serine threonine-protein kinase of Channa striatus improves antioxidant defence in L6 myotubes and attenuates caspase 3 … PK Issac, C Lite, A Guru, M Velayutham, G Kuppusamy, NT Saraswathi, ... Fish physiology and biochemistry 47, 293-311, 2021 | 44 | 2021 |
| Withaferin A targets the membrane of Pseudomonas aeruginosa and mitigates the inflammation in zebrafish larvae; an in vitro and in vivo approach R Murugan, R Rajesh, B Seenivasan, B Haridevamuthu, G Sudhakaran, ... Microbial Pathogenesis 172, 105778, 2022 | 41 | 2022 |
| Insulin signaling pathway assessment by enhancing antioxidant activity due to morin using in vitro rat skeletal muscle L6 myotubes cells PK Issac, R Karan, A Guru, R Pachaiappan, MV Arasu, NA Al-Dhabi, ... Molecular Biology Reports 48, 5857-5872, 2021 | 41 | 2021 |
| Molecular process of glucose uptake and glycogen storage due to hamamelitannin via insulin signalling cascade in glucose metabolism PK Issac, A Guru, SS Chandrakumar, C Lite, NT Saraswathi, MV Arasu, ... Molecular Biology Reports 47 (9), 6727-6740, 2020 | 41 | 2020 |
| GR15 peptide of S-adenosylmethionine synthase (SAMe) from Arthrospira platensis demonstrated antioxidant mechanism against H2O2 induced oxidative stress in in-vitro MDCK cells … M Velayutham, A Guru, MV Arasu, NA Al-Dhabi, KC Choi, P Elumalai, ... Journal of Biotechnology 342, 79-91, 2021 | 39 | 2021 |
| Neuroprotective and antioxidant capability of RW20 peptide from histone acetyltransferases caused by oxidative stress-induced neurotoxicity in in vivo zebrafish larval model N Prabha, A Guru, R Harikrishnan, MK Gatasheh, AA Hatamleh, A Juliet, ... Journal of King Saud University-Science 34 (3), 101861, 2022 | 38 | 2022 |
| NV14 from serine O‐acetyltransferase of cyanobacteria influences the antioxidant enzymes in vitro cells, gene expression against H2O2 and other responses in … M Velayutham, B Ojha, PK Issac, C Lite, A Guru, M Pasupuleti, MV Arasu, ... Cell Biology International 45 (11), 2331-2346, 2021 | 37 | 2021 |
| Daidzein normalized gentamicin-induced nephrotoxicity and associated pro-inflammatory cytokines in MDCK and zebrafish: Possible mechanism of nephroprotection A Guru, G Sudhakaran, M Velayutham, R Murugan, R Pachaiappan, ... Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2022 | 35 | 2022 |
| Deteriorating insulin resistance due to WL15 peptide from cysteine and glycine‐rich protein 2 in high glucose‐induced rat skeletal muscle L6 cells A Guru, PK Issac, NT Saraswathi, VD Seshadri, GA Gabr, J Arockiaraj Cell Biology International 45 (8), 1698-1709, 2021 | 35 | 2021 |
