| GLASS: a comprehensive database for experimentally-validated GPCR-ligand associations WKB Chan, H Zhang, J Yang, JR Brender, J Hur, A Özgür, Y Zhang Bioinformatics, btv302, 2015 | 137 | 2015 |
| Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons HQ Xie, D Liang, KW Leung, VP Chen, KY Zhu, WKB Chan, RCY Choi, ... Journal of Biological Chemistry 285 (15), 11537-11546, 2010 | 64 | 2010 |
| The genetic heterogeneity and drug resistance mechanisms of relapsed refractory multiple myeloma JN Vo, YM Wu, J Mishler, S Hall, R Mannan, L Wang, Y Ning, J Zhou, ... Nature communications 13 (1), 3750, 2022 | 55 | 2022 |
| WDL-RF: predicting bioactivities of ligand molecules acting with G protein-coupled receptors by combining weighted deep learning and random forest J Wu, Q Zhang, W Wu, T Pang, H Hu, WKB Chan, X Ke, Y Zhang Bioinformatics 34 (13), 2271-2282, 2018 | 45 | 2018 |
| The assembly of proline-rich membrane anchor (PRiMA)-linked acetylcholinesterase enzyme: glycosylation is required for enzymatic activity but not for oligomerization VP Chen, RCY Choi, WKB Chan, KW Leung, AJY Guo, GKL Chan, ... Journal of Biological Chemistry 286 (38), 32948-32961, 2011 | 45 | 2011 |
| PRiMA directs a restricted localization of tetrameric AChE at synapses HQ Xie, KW Leung, VP Chen, GKL Chan, SL Xu, AJY Guo, KY Zhu, ... Chemico-biological interactions 187 (1-3), 78-83, 2010 | 37 | 2010 |
| Ontological and bioinformatic analysis of anti-coronavirus drugs and their implication for drug repurposing against COVID-19 Y Liu, W Chan, Z Wang, J Hur, J Xie, H Yu, Y He Preprints 2020030413, 2020 | 33 | 2020 |
| Molecular assembly and biosynthesis of acetylcholinesterase in brain and muscle: the roles of t-peptide, FHB domain, and N-linked glycosylation VP Chen, WKW Luk, WKB Chan, KW Leung, AJY Guo, GKL Chan, SL Xu, ... Frontiers in molecular neuroscience 4, 36, 2011 | 33 | 2011 |
| The PRiMA-linked cholinesterase tetramers are assembled from homodimers: hybrid molecules composed of acetylcholinesterase and butyrylcholinesterase dimers are up-regulated … VP Chen, HQ Xie, WKB Chan, KW Leung, GKL Chan, RCY Choi, S Bon, ... Journal of biological chemistry 285 (35), 27265-27278, 2010 | 33 | 2010 |
| In silico analysis of SARS-CoV-2 proteins as targets for clinically available drugs WKB Chan, KM Olson, JW Wotring, JZ Sexton, HA Carlson, JR Traynor Scientific reports 12 (1), 5320, 2022 | 26 | 2022 |
| Ontological modeling and analysis of experimentally or clinically verified drugs against coronavirus infection YH Yingtong Liu, Junguk Hur, Wallace K. B. Chan, Zhigang Wang, Jiangan Xie ... Scientific Data 8 (16), 2021 | 24 | 2021 |
| Virtual screening of human class-a GPCRs using ligand profiles built on multiple ligand–receptor interactions WKB Chan, Y Zhang Journal of molecular biology 432 (17), 4872-4890, 2020 | 23 | 2020 |
| Precise modelling and interpretation of bioactivities of ligands targeting G protein-coupled receptors J Wu, B Liu, WKB Chan, W Wu, T Pang, H Hu, S Yan, X Ke, Y Zhang Bioinformatics 35 (14), i324-i332, 2019 | 19 | 2019 |
| Computational identification of possible allosteric sites and modulators of the SARS-CoV-2 main protease D DasGupta, WKB Chan, HA Carlson Journal of chemical information and modeling 62 (3), 618-626, 2022 | 16 | 2022 |
| Mixed‐solvent molecular dynamics simulation‐based discovery of a putative allosteric site on regulator of G protein signaling 4 WKB Chan, D DasGupta, HA Carlson, JR Traynor Journal of computational chemistry 42 (30), 2170-2180, 2021 | 10 | 2021 |
| Homologous G protein-coupled receptors boost the modeling and interpretation of bioactivities of ligand molecules J Wu, Y Sun, WKB Chan, Y Zhu, W Zhu, W Huang, H Hu, S Yan, T Pang, ... Journal of chemical information and modeling 60 (3), 1865-1875, 2020 | 9 | 2020 |
| N-linked glycosylation of proline-rich membrane anchor (PRiMA) is not required for assembly and trafficking of globular tetrameric acetylcholinesterase WKB Chan, VP Chen, WKW Luk, RCY Choi, KWK Tsim Neuroscience Letters 523 (1), 71-75, 2012 | 6 | 2012 |
| Application of Mixed-Solvent Molecular Dynamics Simulations for Prediction of Allosteric Sites on G Protein–Coupled Receptors WKB Chan, HA Carlson, JR Traynor Molecular Pharmacology 103 (5), 274-285, 2023 | 5 | 2023 |
| An induction effect of heat shock on the transcript of globular acetylcholinesterase in NG108-15 cells VP Chen, HQ Xie, WKB Chan, KW Leung, RCY Choi, KWK Tsim Chemico-biological interactions 187 (1-3), 106-109, 2010 | 4 | 2010 |
| The assembly of PRiMA-linked acetylcholinesterase: glycosylation is required for enzymatic activity but not for oligomerization VP Chen, RC Choi, WK Chan, KW Leung, AJ Guo, GK Chan, WK Luk, ... J Biol Chem 286, 32948-32961, 2011 | 3 | 2011 |
Yang ZhangNational University of Singaporenus.edu.sg üzerinde doğrulanmış e-posta adresine sahip