Complex cocktails: the evolutionary novelty of venoms NR Casewell, W Wüster, FJ Vonk, RA Harrison, BG Fry Trends in ecology & evolution, 2013 | 978 | 2013 |
The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system FJ Vonk, NR Casewell, CV Henkel, AM Heimberg, HJ Jansen, ... Proceedings of the National Academy of Sciences 110 (51), 20651-20656, 2013 | 536 | 2013 |
The Burmese python genome reveals the molecular basis for extreme adaptation in snakes TA Castoe, APJ de Koning, KT Hall, DC Card, DR Schield, MK Fujita, ... Proceedings of the National Academy of Sciences 110 (51), 20645-20650, 2013 | 334 | 2013 |
Causes and consequences of snake venom variation NR Casewell, TNW Jackson, AH Laustsen, K Sunagar Trends in pharmacological sciences 41 (8), 570-581, 2020 | 331 | 2020 |
Medically important differences in snake venom composition are dictated by distinct postgenomic mechanisms NR Casewell, SC Wagstaff, W Wüster, DAN Cook, FMS Bolton, SI King, ... Proceedings of the National Academy of Sciences 111 (25), 9205-9210, 2014 | 330 | 2014 |
A comparative genomics multitool for scientific discovery and conservation Nature 587 (7833), 240-245, 2020 | 297 | 2020 |
Haemotoxic snake venoms: their functional activity, impact on snakebite victims and pharmaceutical promise J Slagboom, J Kool, RA Harrison, NR Casewell British journal of haematology 177 (6), 947-959, 2017 | 286 | 2017 |
Ending the drought: new strategies for improving the flow of affordable, effective antivenoms in Asia and Africa DJ Williams, JM Gutiérrez, JJ Calvete, W Wüster, K Ratanabanangkoon, ... Journal of proteomics 74 (9), 1735-1767, 2011 | 286 | 2011 |
Multifunctional toxins in snake venoms and therapeutic implications: from pain to hemorrhage and necrosis CR Ferraz, A Arrahman, C Xie, NR Casewell, RJ Lewis, J Kool, ... Frontiers in ecology and evolution 7, 218, 2019 | 224 | 2019 |
Domain loss facilitates accelerated evolution and neofunctionalization of duplicate snake venom metalloproteinase toxin genes NR Casewell, SC Wagstaff, RA Harrison, C Renjifo, W Wüster Molecular biology and evolution 28 (9), 2637-2649, 2011 | 224 | 2011 |
Comparative venom gland transcriptome surveys of the saw-scaled vipers (Viperidae: Echis) reveal substantial intra-family gene diversity and novel venom … NR Casewell, RA Harrison, W Wüster, SC Wagstaff BMC genomics 10, 1-12, 2009 | 194 | 2009 |
The structural and functional diversification of the Toxicofera reptile venom system BG Fry, NR Casewell, W Wüster, N Vidal, B Young, TNW Jackson Toxicon 60 (4), 434-448, 2012 | 192 | 2012 |
Widespread convergence in toxin resistance by predictable molecular evolution B Ujvari, NR Casewell, K Sunagar, K Arbuckle, W Wüster, N Lo, ... Proceedings of the National Academy of Sciences 112 (38), 11911-11916, 2015 | 163 | 2015 |
Convergent evolution of pain-inducing defensive venom components in spitting cobras TD Kazandjian, D Petras, SD Robinson, J van Thiel, HW Greene, ... Science 371 (6527), 386-390, 2021 | 132 | 2021 |
Dynamic evolution of venom proteins in squamate reptiles NR Casewell, GA Huttley, W Wüster Nature communications 3 (1), 1066, 2012 | 121 | 2012 |
Preclinical antivenom-efficacy testing reveals potentially disturbing deficiencies of snakebite treatment capability in East Africa RA Harrison, GO Oluoch, S Ainsworth, J Alsolaiss, F Bolton, AS Arias, ... PLoS neglected tropical diseases 11 (10), e0005969, 2017 | 120 | 2017 |
Snake venom gland organoids Y Post, J Puschhof, J Beumer, HM Kerkkamp, MAG de Bakker, ... Cell 180 (2), 233-247. e21, 2020 | 116 | 2020 |
Pre-Clinical Assays Predict Pan-African Echis Viper Efficacy for a Species-Specific Antivenom NR Casewell, DAN Cook, SC Wagstaff, A Nasidi, N Durfa, W Wüster, ... PLoS neglected tropical diseases 4 (10), e851, 2010 | 116 | 2010 |
Expression of venom gene homologs in diverse python tissues suggests a new model for the evolution of snake venom J Reyes-Velasco, DC Card, AL Andrew, KJ Shaney, RH Adams, ... Molecular biology and evolution 32 (1), 173-183, 2015 | 115 | 2015 |
A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite LO Albulescu, C Xie, S Ainsworth, J Alsolaiss, E Crittenden, CA Dawson, ... Nature communications 11 (1), 6094, 2020 | 113 | 2020 |