α-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B DG Ferreira, M Temido-Ferreira, H Vicente Miranda, VL Batalha, ... Nature neuroscience 20 (11), 1569-1579, 2017 | 298 | 2017 |
Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies H Vicente Miranda, ÉM Szegő, LMA Oliveira, C Breda, E Darendelioglu, ... Brain 140 (5), 1399-1419, 2017 | 226 | 2017 |
Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson’s disease L Tönges, T Frank, L Tatenhorst, KA Saal, JC Koch, ÉM Szegő, M Bähr, ... Brain 135 (11), 3355-3370, 2012 | 207 | 2012 |
The NAD‐dependent deacetylase sirtuin 2 is a suppressor of microglial activation and brain inflammation TF Pais, ÉM Szegő, O Marques, L Miller‐Fleming, P Antas, P Guerreiro, ... The EMBO journal 32 (19), 2603-2616, 2013 | 196 | 2013 |
The mechanism of sirtuin 2–mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease RM de Oliveira, H Vicente Miranda, L Francelle, R Pinho, ÉM Szegö, ... PLoS biology 15 (3), e2000374, 2017 | 189 | 2017 |
Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein R Pinho, I Paiva, KG Jerčić, L Fonseca-Ornelas, E Gerhardt, C Fahlbusch, ... Human molecular genetics 28 (1), 31-50, 2019 | 171 | 2019 |
Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage I Paiva, R Pinho, MA Pavlou, M Hennion, P Wales, AL Schütz, A Rajput, ... Human molecular genetics 26 (12), 2231-2246, 2017 | 163 | 2017 |
Estrogen induces estrogen receptor α-dependent cAMP response element-binding protein phosphorylation via mitogen activated protein kinase pathway in basal forebrain cholinergic … ÉM Szegő, K Barabás, J Balog, N Szilágyi, KS Korach, G Juhász, ... Journal of Neuroscience 26 (15), 4104-4110, 2006 | 144 | 2006 |
α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner G Yin, TL Da Fonseca, SE Eisbach, AM Anduaga, C Breda, ML Orcellet, ... Neurobiology of disease 70, 149-161, 2014 | 104 | 2014 |
Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity A Villar-Piqué, T Lopes da Fonseca, R Sant’Anna, ÉM Szegö, ... Proceedings of the National Academy of Sciences 113 (42), E6506-E6515, 2016 | 98 | 2016 |
The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes V Lemos, RM De Oliveira, L Naia, É Szegö, E Ramos, S Pinho, F Magro, ... Human molecular genetics 26 (21), 4105-4117, 2017 | 93 | 2017 |
Facilitation of spike-wave discharge activity by lipopolysaccharides in Wistar Albino Glaxo/Rijswijk rats Z Kovács, KA Kékesi, N Szilágyi, I Abrahám, D Székács, N Király, E Papp, ... Neuroscience 140 (2), 731-742, 2006 | 82 | 2006 |
A mouse model of anxiety molecularly characterized by altered protein networks in the brain proteome ÉM Szegő, T Janáky, Z Szabó, A Csorba, H Kompagne, G Müller, G Lévay, ... European Neuropsychopharmacology 20 (2), 96-111, 2010 | 81 | 2010 |
Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function I Paiva, G Jain, DF Lázaro, KG Jerčić, T Hentrich, C Kerimoglu, R Pinho, ... Neurobiology of disease 119, 121-135, 2018 | 74 | 2018 |
AAV. shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo KA Saal, JC Koch, L Tatenhorst, ÉM Szegő, VT Ribas, U Michel, M Bähr, ... Neurobiology of disease 73, 150-162, 2015 | 74 | 2015 |
Altered functional protein networks in the prefrontal cortex and amygdala of victims of suicide KA Kekesi, G Juhasz, A Simor, P Gulyassy, ÉM Szegő, E Hunyadi-Gulyas, ... PloS one 7 (12), e50532, 2012 | 73 | 2012 |
Translocator protein ligand protects against neurodegeneration in the MPTP mouse model of Parkinsonism J Gong, ÉM Szego, A Leonov, E Benito, S Becker, A Fischer, ... Journal of Neuroscience 39 (19), 3752-3769, 2019 | 69 | 2019 |
Rho kinase inhibition by fasudil in the striatal 6-hydroxydopamine lesion mouse model of Parkinson disease L Tatenhorst, L Tönges, KA Saal, JC Koch, ÉM Szegő, M Bähr, P Lingor Journal of Neuropathology & Experimental Neurology 73 (8), 770-779, 2014 | 57 | 2014 |
Idebenone and resveratrol extend lifespan and improve motor function of HtrA2 knockout mice E Gerhardt, S Gräber, ÉM Szegő, N Moisoi, LM Martins, TF Outeiro, ... PLoS One 6 (12), e28855, 2011 | 57 | 2011 |
Cytosolic trapping of a mitochondrial heat shock protein is an early pathological event in synucleinopathies ÉM Szegő, A Dominguez-Meijide, E Gerhardt, A König, DJ Koss, W Li, ... Cell reports 28 (1), 65-77. e6, 2019 | 52 | 2019 |