Humanization of the anti-CD18 antibody 6.7: an unexpected effect of a framework residue in binding to antigen C Caldas, V Coelho, J Kalil, AM Moro, AQ Maranhão, MM Brı́gido Molecular immunology 39 (15), 941-952, 2003 | 183 | 2003 |
Biosimilars advancements: moving on to the future LR Tsuruta, M Lopes dos Santos, AM Moro Biotechnology progress 31 (5), 1139-1149, 2015 | 101 | 2015 |
Advances and challenges in therapeutic monoclonal antibodies drug development ML Santos, W Quintilio, TM Manieri, LR Tsuruta, AM Moro Brazilian Journal of Pharmaceutical Sciences 54, e01007, 2018 | 83 | 2018 |
Animal cell technology: from biopharmaceuticals to gene therapy L Castilho, A Moraes, E Augusto, M Butler Garland Science, 2008 | 79 | 2008 |
Pathogenic Leptospira species acquire factor H and vitronectin via the surface protein LcpA LB da Silva, LS Miragaia, LCD Breda, CM Abe, MCB Schmidt, AM Moro, ... Infection and immunity 83 (3), 888-897, 2015 | 66 | 2015 |
Design and synthesis of germline-based hemi-humanized single-chain Fv against the CD18 surface antigen C Caldas, VPCV Coelho, DJ Rigden, G Neschich, AM Moro, MM Brígido Protein Engineering 13 (5), 353-360, 2000 | 48 | 2000 |
Bispecific monoclonal antibody anti‐CD3 X anti‐tenascin: An immunotherapeutic agent for human glioma LD Bonino, LB De Monte, GC Spagnoli, R Vola, M Mariani, D Barone, ... International Journal of cancer 61 (4), 509-515, 1995 | 44 | 1995 |
Blocking FGF2 with a new specific monoclonal antibody impairs angiogenesis and experimental metastatic melanoma, suggesting a potential role in adjuvant settings RB de Aguiar, CB Parise, CRT Souza, C Braggion, W Quintilio, AM Moro, ... Cancer letters 371 (2), 151-160, 2016 | 37 | 2016 |
LUVs recovered with chitosan: a new preparation for vaccine delivery LB Marón, CP Covas, NP Da Silveira, A Pohlmann, O Mertins, LN Tatsuo, ... Journal of Liposome Research 17 (3-4), 155-163, 2007 | 34 | 2007 |
Multiparametric analyses of hybridoma growth on glass cylinders in a packed-bed bioreactor system with internal aeration. Serum-supplemented and serum-free media comparison for … AM Moro, MTA Rodrigues, MN Gouvea, MLZ Silvestri, JE Kalil, I Raw Journal of immunological methods 176 (1), 67-77, 1994 | 32 | 1994 |
Comparison of humanized IgG and FvFc anti-CD3 monoclonal antibodies expressed in CHO cells F Serpieri, A Inocencio, JM de Oliveira, AA Pimenta, A Garbuio, J Kalil, ... Molecular biotechnology 45, 218-225, 2010 | 30 | 2010 |
Binding affinity, specificity and comparative biodistribution of the parental murine monoclonal antibody MX35 (Anti-NaPi2b) and its humanized version Rebmab200 S Lindegren, LNS Andrade, T Bäck, CML Machado, BB Horta, ... PLoS One 10 (5), e0126298, 2015 | 29 | 2015 |
Production of the first effective hyperimmune equine serum antivenom against Africanized bees KS Santos, MA Stephano, JR Marcelino, VMR Ferreira, T Rocha, ... PLoS One 8 (11), e79971, 2013 | 29 | 2013 |
A phase II trial with anti-Lewis-Y monoclonal antibody (hu3S193) for the treatment of platinum resistant/refractory ovarian, fallopian tube and primary peritoneal carcinoma O Smaletz, MDPE Diz, CC Do Carmo, J Sabbaga, GF Cunha-Junior, ... Gynecologic oncology 138 (2), 272-277, 2015 | 28 | 2015 |
Rebmab200, a humanized monoclonal antibody targeting the sodium phosphate transporter NaPi2b displays strong immune mediated cytotoxicity against cancer: a novel reagent for … ML dos Santos, FP Yeda, LR Tsuruta, BB Horta, AA Pimenta Jr, TL Degaki, ... PloS one 8 (7), e70332, 2013 | 28 | 2013 |
Radiolabeled NGR phage display peptide sequence for tumor targeting BL Faintuch, EA Oliveira, RC Targino, AM Moro Applied Radiation and Isotopes 86, 41-45, 2014 | 27 | 2014 |
Novel humanized anti-CD3 antibodies induce a predominantly immunoregulatory profile in human peripheral blood mononuclear cells HM Silva, PMMM Vieira, PLN Costa, BMS Pimentel, AM Moro, J Kalil, ... Immunology Letters 125 (2), 129-136, 2009 | 21 | 2009 |
Anti-digoxin Fab variants generated by phage display VM Murata, MCB Schmidt, J Kalil, LR Tsuruta, AM Moro Molecular biotechnology 54, 269-277, 2013 | 20 | 2013 |
Generation of a Chinese hamster ovary cell line producing recombinant human glucocerebrosidase JB Novo, L Morganti, AM Moro, AF Paes Leme, SMT Serrano, I Raw, ... BioMed Research International 2012 (1), 875383, 2012 | 20 | 2012 |
Glucose uptake rate as a tool to estimate hybridoma growth in a packed bed bioreactor MTA Rodrigues, PR Vilaça, A Garbuio, M Takagi, S Barbosa Jr, P Léo, ... Bioprocess Engineering 21, 543-546, 1999 | 20 | 1999 |