Developing vaccines in the era of genomics: a decade of reverse vaccinology KL Seib, X Zhao, R Rappuoli Clinical Microbiology and Infection 18, 109-116, 2012 | 268 | 2012 |
Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans D Serruto, T Spadafina, L Ciucchi, LA Lewis, S Ram, M Tontini, L Santini, ... Proceedings of the National Academy of Sciences 107 (8), 3770-3775, 2010 | 263 | 2010 |
Neisseria meningitidis is structured in clades associated with restriction modification systems that modulate homologous recombination S Budroni, E Siena, JCD Hotopp, KL Seib, D Serruto, C Nofroni, ... Proceedings of the National Academy of Sciences 108 (11), 4494-4499, 2011 | 251 | 2011 |
Vaccinology in the genome era CD Rinaudo, JL Telford, R Rappuoli, KL Seib The Journal of clinical investigation 119 (9), 2515-2525, 2009 | 211 | 2009 |
Phasevarions Mediate Random Switching of Gene Expression in Pathogenic Neisseria YN Srikhanta, SJ Dowideit, JL Edwards, ML Falsetta, HJ Wu, OB Harrison, ... PLoS pathogens 5 (4), e1000400, 2009 | 199 | 2009 |
Vaccines, reverse vaccinology, and bacterial pathogenesis I Delany, R Rappuoli, KL Seib Cold Spring Harbor perspectives in medicine 3 (5), a012476, 2013 | 185 | 2013 |
Defenses against Oxidative Stress in Neisseria gonorrhoeae: a System Tailored for a Challenging Environment KL Seib, HJ Wu, SP Kidd, MA Apicella, MP Jennings, AG McEwan Microbiology and molecular biology reviews 70 (2), 344-361, 2006 | 183 | 2006 |
Transcriptome Analysis of Neisseria meningitidis in Human Whole Blood and Mutagenesis Studies Identify Virulence Factors Involved in … H Echenique-Rivera, A Muzzi, E Del Tordello, KL Seib, P Francois, ... PLoS pathogens 7 (5), e1002027, 2011 | 176 | 2011 |
The Serogroup B Meningococcal Vaccine Bexsero Elicits Antibodies to Neisseria gonorrhoeae EA Semchenko, A Tan, R Borrow, KL Seib Clinical Infectious Diseases 69 (7), 1101-1111, 2019 | 174 | 2019 |
The key role of genomics in modern vaccine and drug design for emerging infectious diseases KL Seib, G Dougan, R Rappuoli PLoS genetics 5 (10), e1000612, 2009 | 167 | 2009 |
Defenses against oxidative stress in Neisseria gonorrhoeae and Neisseria meningitidis: distinctive systems for different lifestyles KL Seib, HJ Tseng, AG McEwan, MA Apicella, MP Jennings The Journal of infectious diseases 190 (1), 136-147, 2004 | 165 | 2004 |
Factor H-binding protein is important for meningococcal survival in human whole blood and serum and in the presence of the antimicrobial peptide LL-37 KL Seib, D Serruto, F Oriente, I Delany, J Adu-Bobie, D Veggi, B Arico, ... Infection and immunity 77 (1), 292-299, 2009 | 125 | 2009 |
The RNA chaperone Hfq is involved in stress response and virulence in Neisseria meningitidis and is a pleiotropic regulator of protein expression L Fantappie, MM Metruccio, KL Seib, ... Infect Immun 77, 1842-1853, 2009 | 118* | 2009 |
Characterization of the OxyR regulon of Neisseria gonorrhoeae KL Seib, HJ Wu, YN Srikhanta, JL Edwards, ML Falsetta, AJ Hamilton, ... Molecular microbiology 63 (1), 54-68, 2007 | 116 | 2007 |
Pilin glycosylation in Neisseria meningitidis occurs by a similar pathway to wzy-dependent O-antigen biosynthesis in Escherichia coli PM Power, KL Seib, MP Jennings Biochemical and biophysical research communications 347 (4), 904-908, 2006 | 109 | 2006 |
The potential impact of vaccination on the prevalence of gonorrhea AP Craig, RT Gray, JL Edwards, MA Apicella, MP Jennings, DP Wilson, ... Vaccine 33 (36), 4520-4525, 2015 | 108 | 2015 |
Is gonococcal disease preventable? The importance of understanding immunity and pathogenesis in vaccine development JL Edwards, MP Jennings, MA Apicella, KL Seib Critical reviews in microbiology 42 (6), 928-941, 2016 | 102 | 2016 |
PerR controls Mn‐dependent resistance to oxidative stress in Neisseria gonorrhoeae HJ Wu, KL Seib, YN Srikhanta, SP Kidd, JL Edwards, TL Maguire, ... Molecular microbiology 60 (2), 401-416, 2006 | 99 | 2006 |
Neisseria meningitidis factor H-binding protein fHbp: a key virulence factor and vaccine antigen KL Seib, M Scarselli, M Comanducci, D Toneatto, V Masignani Expert review of vaccines 14 (6), 841-859, 2015 | 86 | 2015 |
Characterization of diverse subvariants of the meningococcal factor H (fH) binding protein for their ability to bind fH, to mediate serum resistance, and to induce bactericidal … KL Seib, B Brunelli, B Brogioni, E Palumbo, S Bambini, A Muzzi, ... Infection and immunity 79 (2), 970-981, 2011 | 80 | 2011 |