Ligand binding and aggregation of pathogenic SOD1 GSA Wright, SV Antonyuk, NM Kershaw, RW Strange, S Samar Hasnain Nature communications 4 (1), 1758, 2013 | 112 | 2013 |
The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation MJ Capper, GSA Wright, L Barbieri, E Luchinat, E Mercatelli, L McAlary, ... Nature communications 9 (1), 1693, 2018 | 102 | 2018 |
Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life JA Austin, GSA Wright, S Watanabe, JG Grossmann, SV Antonyuk, ... Proceedings of the National Academy of Sciences 111 (11), 4309-4314, 2014 | 85 | 2014 |
The biophysics of superoxide dismutase-1 and amyotrophic lateral sclerosis GSA Wright, SV Antonyuk, SS Hasnain Quarterly reviews of biophysics 52, e12, 2019 | 79 | 2019 |
Modulation of LAT1 (SLC7A5) transporter activity and stability by membrane cholesterol D Dickens, GN Chiduza, GSA Wright, M Pirmohamed, SV Antonyuk, ... Scientific reports 7 (1), 43580, 2017 | 78 | 2017 |
Architecture of the complete oxygen-sensing FixL-FixJ two-component signal transduction system GSA Wright, A Saeki, T Hikima, Y Nishizono, T Hisano, M Kamaya, ... Science Signaling 11 (525), eaaq0825, 2018 | 52 | 2018 |
Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS FA Sala, GSA Wright, SV Antonyuk, RC Garratt, SS Hasnain PLoS biology 17 (2), e3000141, 2019 | 48 | 2019 |
Crystal structure of the Japanese encephalitis virus capsid protein T Poonsiri, GSA Wright, T Solomon, SV Antonyuk Viruses 11 (7), 623, 2019 | 46 | 2019 |
A faulty interaction between SOD1 and hCCS in neurodegenerative disease GSA Wright, SV Antonyuk, SS Hasnain Scientific reports 6 (1), 27691, 2016 | 46 | 2016 |
Structural study of the C-terminal domain of nonstructural protein 1 from Japanese encephalitis virus T Poonsiri, GSA Wright, MS Diamond, L Turtle, T Solomon, SV Antonyuk Journal of virology 92 (7), 10.1128/jvi. 01868-17, 2018 | 38 | 2018 |
Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy V Chantadul, GSA Wright, K Amporndanai, M Shahid, SV Antonyuk, ... Communications Biology 3 (1), 97, 2020 | 36 | 2020 |
Reliable scale-up of membrane protein over-expression by bacterial auto-induction: from microwell plates to pilot scale fermentations SE Deacon, PCJ Roach, VLG Postis, GSA Wright, X Xia, SEV Phillips, ... Molecular membrane biology 25 (8), 588-598, 2008 | 36 | 2008 |
A high-throughput assay of membrane protein stability VLG Postis, SE Deacon, PCJ Roach, GSA Wright, X Xia, GSA Wright, ... Molecular membrane biology 25 (8), 617-624, 2008 | 35 | 2008 |
Assessment of ligand binding at a site relevant to SOD 1 oxidation and aggregation R Manjula, GSA Wright, RW Strange, B Padmanabhan FEBS letters 592 (10), 1725-1737, 2018 | 33 | 2018 |
The structural plasticity of the human copper chaperone for SOD1: Insights from combined size-exclusion chromatographic and solution X-ray scattering studies GSA Wright, SS Hasnain, JG Grossmann Biochemical Journal 439 (1), 39-44, 2011 | 30 | 2011 |
Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota AS Luis, A Baslé, DP Byrne, GSA Wright, JA London, C Jin, NG Karlsson, ... Nature chemical biology 18 (8), 841-849, 2022 | 29 | 2022 |
Purification and structural characterization of aggregation-prone human TDP-43 involved in neurodegenerative diseases GSA Wright, TF Watanabe, K Amporndanai, SS Plotkin, NR Cashman, ... Iscience 23 (6), 2020 | 29 | 2020 |
LAT1 (SLC7A5) and CD98hc (SLC3A2) complex dynamics revealed by single-particle cryo-EM GN Chiduza, RM Johnson, GSA Wright, SV Antonyuk, SP Muench, ... Biological Crystallography 75 (7), 660-669, 2019 | 23 | 2019 |
Molecular and pharmacological chaperones for SOD1 GSA Wright Biochemical Society Transactions 48 (4), 1795-1806, 2020 | 21 | 2020 |
X-ray crystallography and computational docking for the detection and development of protein–ligand interactions NM Kershaw, GSA Wright, R Sharma, SV Antonyuk, RW Strange, ... Current medicinal chemistry 20 (4), 569-575, 2013 | 21 | 2013 |